Neuropeptide Y receptor Y5: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Neuropeptide Y receptor type 5''' is a [[protein]] that in humans is encoded by the ''NPY5R'' [[gene]].<ref name="pmid8700207">{{cite journal | vauthors = Gerald C, Walker MW, Criscione L, Gustafson EL, Batzl-Hartmann C, Smith KE, Vaysse P, Durkin MM, Laz TM, Linemeyer DL, Schaffhauser AO, Whitebread S, Hofbauer KG, Taber RI, Branchek TA, Weinshank RL | title = A receptor subtype involved in neuropeptide-Y-induced food intake | journal = Nature | volume = 382 | issue = 6587 | pages = 168–71 | date = Jul 1996 | pmid = 8700207 | pmc =  | doi = 10.1038/382168a0 }}</ref><ref name="pmid9417917">{{cite journal | vauthors = Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA | title = Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY | journal = Genomics | volume = 46 | issue = 2 | pages = 287–90 | date = Dec 1997 | pmid = 9417917 | pmc =  | doi = 10.1006/geno.1997.5024 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NPY5R neuropeptide Y receptor Y5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4889| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Selective ligands ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Neuropeptide Y receptor Y5
| HGNCid = 7958
| Symbol = NPY5R
| AltSymbols =; NPYR5
| OMIM = 602001
| ECnumber = 
| Homologene = 21241
| MGIid = 108082
| GeneAtlas_image1 = PBB_GE_NPY5R_207400_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0001601 |text = peptide YY receptor activity}} {{GNF_GO|id=GO:0001602 |text = pancreatic polypeptide receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007268 |text = synaptic transmission}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4889
    | Hs_Ensembl = ENSG00000164129
    | Hs_RefseqProtein = NP_006165
    | Hs_RefseqmRNA = NM_006174
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 4
    | Hs_GenLoc_start = 164484541
    | Hs_GenLoc_end = 164492534
    | Hs_Uniprot = Q15761
    | Mm_EntrezGene = 18168
    | Mm_Ensembl = ENSMUSG00000044014
    | Mm_RefseqmRNA = NM_016708
    | Mm_RefseqProtein = NP_057917
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 69608954
    | Mm_GenLoc_end = 69617083
    | Mm_Uniprot = Q543U8
  }}
}}
'''Neuropeptide Y receptor Y5''', also known as '''NPY5R''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NPY5R neuropeptide Y receptor Y5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4889| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
=== Agonists ===
{{PBB_Summary
* [[Neuropeptide Y]] (endogenous agonist, non subtype selective)
| section_title =
* BWX-46 (selective NPY<sub>5</sub> agonist, CAS# 172997-92-1)
| summary_text =
* [[Peptide YY]]
}}


==See also==
=== Antagonists ===
* CGP-71683 (CAS# 192322-50-2)
* FMS-586<ref name="pmid16436501">{{cite journal | vauthors = Kakui N, Tanaka J, Tabata Y, Asai K, Masuda N, Miyara T, Nakatani Y, Ohsawa F, Nishikawa N, Sugai M, Suzuki M, Aoki K, Kitaguchi H | title = Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 317 | issue = 2 | pages = 562–70 | date = May 2006 | pmid = 16436501 | doi = 10.1124/jpet.105.099705 }}</ref>
* L-152,804 (CAS# 6508-43-6)
* [[Lu AA-33810]]<ref name="pmid19098165">{{cite journal | vauthors = Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG, Marsteller DA, Marzabadi MR, Papp M, Overstreet DH, Gerald CP, Craig DA | title = <nowiki>The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity</nowiki> | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 328 | issue = 3 | pages = 900–11 | date = Mar 2009 | pmid = 19098165 | doi = 10.1124/jpet.108.144634 }}</ref>
* MK-0557<ref name="pmid17979781">{{cite journal | vauthors = MacNeil DJ | title = NPY Y1 and Y5 receptor selective antagonists as anti-obesity drugs | journal = Current Topics in Medicinal Chemistry | volume = 7 | issue = 17 | pages = 1721–33 | year = 2007 | pmid = 17979781 | doi = 10.2174/156802607782341028 | url = http://www.bentham-direct.org/pages/content.php?CTMC/2007/00000007/00000017/0009R.SGM }}</ref>
* NTNCB (CAS# 486453-65-0)<ref name="pmid12067557">{{cite journal | vauthors = Islam I, Dhanoa D, Finn J, Du P, Walker MW, Salon JA, Zhang J, Gluchowski C | title = Discovery of potent and selective small molecule NPY Y5 receptor antagonists | journal = Bioorganic & Medicinal Chemistry Letters | volume = 12 | issue = 13 | pages = 1767–9 | date = Jul 2002 | pmid = 12067557 | doi = 10.1016/S0960-894X(02)00287-1 | url = http://linkinghub.elsevier.com/retrieve/pii/S0960894X02002871 }}</ref>
* [[Velneperit]] (S-2367)
 
== See also ==
* [[Neuropeptide Y receptor]]
* [[Neuropeptide Y receptor]]
{{clear}}


==References==
== References ==
{{reflist|2}}
{{Reflist|33em}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin|33em}}
{{PBB_Further_reading
* {{cite journal | vauthors = Parker E, Van Heek M, Stamford A | title = Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status | journal = European Journal of Pharmacology | volume = 440 | issue = 2-3 | pages = 173–87 | date = Apr 2002 | pmid = 12007534 | doi = 10.1016/S0014-2999(02)01427-9 }}
| citations =
* {{cite journal | vauthors = Hu Y, Bloomquist BT, Cornfield LJ, DeCarr LB, Flores-Riveros JR, Friedman L, Jiang P, Lewis-Higgins L, Sadlowski Y, Schaefer J, Velazquez N, McCaleb ML | title = Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior | journal = The Journal of Biological Chemistry | volume = 271 | issue = 42 | pages = 26315–9 | date = Oct 1996 | pmid = 8824284 | doi = 10.1074/jbc.271.42.26315 }}
*{{cite journal | author=Parker E, Van Heek M, Stamford A |title=Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status. |journal=Eur. J. Pharmacol. |volume=440 |issue= 2-3 |pages= 173-87 |year= 2002 |pmid= 12007534 |doi= }}
* {{cite journal | vauthors = Herzog H, Darby K, Ball H, Hort Y, Beck-Sickinger A, Shine J | title = Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation | journal = Genomics | volume = 41 | issue = 3 | pages = 315–9 | date = May 1997 | pmid = 9169127 | doi = 10.1006/geno.1997.4684 }}
*{{cite journal  | author=Gerald C, Walker MW, Criscione L, ''et al.'' |title=A receptor subtype involved in neuropeptide-Y-induced food intake. |journal=Nature |volume=382 |issue= 6587 |pages= 168-71 |year= 1996 |pmid= 8700207 |doi= 10.1038/382168a0 }}
* {{cite journal | vauthors = Nichol KA, Morey A, Couzens MH, Shine J, Herzog H, Cunningham AM | title = Conservation of expression of neuropeptide Y5 receptor between human and rat hypothalamus and limbic regions suggests an integral role in central neuroendocrine control | journal = The Journal of Neuroscience | volume = 19 | issue = 23 | pages = 10295–304 | date = Dec 1999 | pmid = 10575027 | doi =  }}
*{{cite journal | author=Hu Y, Bloomquist BT, Cornfield LJ, ''et al.'' |title=Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior. |journal=J. Biol. Chem. |volume=271 |issue= 42 |pages= 26315-9 |year= 1996 |pmid= 8824284 |doi= }}
* {{cite journal | vauthors = Rodriguez M, Audinot V, Dromaint S, Macia C, Lamamy V, Beauverger P, Rique H, Imbert J, Nicolas JP, Boutin JA, Galizzi JP | title = Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform | journal = The Biochemical Journal | volume = 369 | issue = Pt 3 | pages = 667–73 | date = Feb 2003 | pmid = 12398768 | pmc = 1223119 | doi = 10.1042/BJ20020739 }}
*{{cite journal | author=Herzog H, Darby K, Ball H, ''et al.'' |title=Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation. |journal=Genomics |volume=41 |issue= 3 |pages= 315-9 |year= 1997 |pmid= 9169127 |doi= 10.1006/geno.1997.4684 }}
* {{cite journal | vauthors = Berglund MM, Schober DA, Statnick MA, McDonald PH, Gehlert DR | title = The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 306 | issue = 1 | pages = 147–56 | date = Jul 2003 | pmid = 12665544 | doi = 10.1124/jpet.103.051227 }}
*{{cite journal | author=Lutz CM, Richards JE, Scott KL, ''et al.'' |title=Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY. |journal=Genomics |volume=46 |issue= 2 |pages= 287-90 |year= 1998 |pmid= 9417917 |doi= 10.1006/geno.1997.5024 }}
* {{cite journal | vauthors = Beauverger P, Rodriguez M, Nicolas JP, Audinot V, Lamamy V, Dromaint S, Nagel N, Macia C, Léopold O, Galizzi JP, Caignard DH, Aldana I, Monge A, Chomarat P, Boutin JA | title = Functional characterization of human neuropeptide Y receptor subtype five specific antagonists using a luciferase reporter gene assay | journal = Cellular Signalling | volume = 17 | issue = 4 | pages = 489–96 | date = Apr 2005 | pmid = 15601626 | doi = 10.1016/j.cellsig.2004.09.006 }}
*{{cite journal  | author=Nichol KA, Morey A, Couzens MH, ''et al.'' |title=Conservation of expression of neuropeptide Y5 receptor between human and rat hypothalamus and limbic regions suggests an integral role in central neuroendocrine control. |journal=J. Neurosci. |volume=19 |issue= 23 |pages= 10295-304 |year= 1999 |pmid= 10575027 |doi=  }}
* {{cite journal | vauthors = Movafagh S, Hobson JP, Spiegel S, Kleinman HK, Zukowska Z | title = Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors | journal = FASEB Journal | volume = 20 | issue = 11 | pages = 1924–6 | date = Sep 2006 | pmid = 16891622 | doi = 10.1096/fj.05-4770fje }}
*{{cite journal | author=Rodriguez M, Audinot V, Dromaint S, ''et al.'' |title=Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform. |journal=Biochem. J. |volume=369 |issue= Pt 3 |pages= 667-73 |year= 2003 |pmid= 12398768 |doi= 10.1042/BJ20020739 }}
* {{cite journal | vauthors = Coletta DK, Schneider J, Stern MP, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP | title = Association of neuropeptide Y receptor Y5 polymorphisms with dyslipidemia in Mexican Americans | journal = Obesity | volume = 15 | issue = 4 | pages = 809–15 | date = Apr 2007 | pmid = 17426313 | doi = 10.1038/oby.2007.610 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Berglund MM, Schober DA, Statnick MA, ''et al.'' |title=The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction. |journal=J. Pharmacol. Exp. Ther. |volume=306 |issue= 1 |pages= 147-56 |year= 2003 |pmid= 12665544 |doi= 10.1124/jpet.103.051227 }}
*{{cite journal | author=Beauverger P, Rodriguez M, Nicolas JP, ''et al.'' |title=Functional characterization of human neuropeptide Y receptor subtype five specific antagonists using a luciferase reporter gene assay. |journal=Cell. Signal. |volume=17 |issue= 4 |pages= 489-96 |year= 2005 |pmid= 15601626 |doi= 10.1016/j.cellsig.2004.09.006 }}
*{{cite journal | author=Movafagh S, Hobson JP, Spiegel S, ''et al.'' |title=Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors. |journal=FASEB J. |volume=20 |issue= 11 |pages= 1924-6 |year= 2006 |pmid= 16891622 |doi= 10.1096/fj.05-4770fje }}
*{{cite journal | author=Coletta DK, Schneider J, Stern MP, ''et al.'' |title=Association of neuropeptide Y receptor Y5 polymorphisms with dyslipidemia in Mexican Americans. |journal=Obesity (Silver Spring, Md.) |volume=15 |issue= 4 |pages= 809-15 |year= 2007 |pmid= 17426313 |doi= }}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
== External links ==
{{G protein-coupled receptors}}
* {{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2372 | title = Neuropeptide Y Receptors: Y<sub>5</sub> | accessdate = | authorlink = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | archiveurl = | archivedate = | quote = }}
 
{{G protein-coupled receptors|g1}}
{{Neuropeptidergics}}
 
[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}
 
 
{{transmembranereceptor-stub}}

Revision as of 15:53, 6 September 2017

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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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View/Edit Human

Neuropeptide Y receptor type 5 is a protein that in humans is encoded by the NPY5R gene.[1][2][3]

Selective ligands

Agonists

Antagonists

See also

References

  1. ↑ Gerald C, Walker MW, Criscione L, Gustafson EL, Batzl-Hartmann C, Smith KE, Vaysse P, Durkin MM, Laz TM, Linemeyer DL, Schaffhauser AO, Whitebread S, Hofbauer KG, Taber RI, Branchek TA, Weinshank RL (Jul 1996). "A receptor subtype involved in neuropeptide-Y-induced food intake". Nature. 382 (6587): 168–71. doi:10.1038/382168a0. PMID 8700207.
  2. ↑ Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA (Dec 1997). "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY". Genomics. 46 (2): 287–90. doi:10.1006/geno.1997.5024. PMID 9417917.
  3. ↑ "Entrez Gene: NPY5R neuropeptide Y receptor Y5".
  4. ↑ Kakui N, Tanaka J, Tabata Y, Asai K, Masuda N, Miyara T, Nakatani Y, Ohsawa F, Nishikawa N, Sugai M, Suzuki M, Aoki K, Kitaguchi H (May 2006). "Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor". The Journal of Pharmacology and Experimental Therapeutics. 317 (2): 562–70. doi:10.1124/jpet.105.099705. PMID 16436501.
  5. ↑ Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG, Marsteller DA, Marzabadi MR, Papp M, Overstreet DH, Gerald CP, Craig DA (Mar 2009). "The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity". The Journal of Pharmacology and Experimental Therapeutics. 328 (3): 900–11. doi:10.1124/jpet.108.144634. PMID 19098165.
  6. ↑ MacNeil DJ (2007). "NPY Y1 and Y5 receptor selective antagonists as anti-obesity drugs". Current Topics in Medicinal Chemistry. 7 (17): 1721–33. doi:10.2174/156802607782341028. PMID 17979781.
  7. ↑ Islam I, Dhanoa D, Finn J, Du P, Walker MW, Salon JA, Zhang J, Gluchowski C (Jul 2002). "Discovery of potent and selective small molecule NPY Y5 receptor antagonists". Bioorganic & Medicinal Chemistry Letters. 12 (13): 1767–9. doi:10.1016/S0960-894X(02)00287-1. PMID 12067557.

Further reading

  • Parker E, Van Heek M, Stamford A (Apr 2002). "Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status". European Journal of Pharmacology. 440 (2–3): 173–87. doi:10.1016/S0014-2999(02)01427-9. PMID 12007534.
  • Hu Y, Bloomquist BT, Cornfield LJ, DeCarr LB, Flores-Riveros JR, Friedman L, Jiang P, Lewis-Higgins L, Sadlowski Y, Schaefer J, Velazquez N, McCaleb ML (Oct 1996). "Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior". The Journal of Biological Chemistry. 271 (42): 26315–9. doi:10.1074/jbc.271.42.26315. PMID 8824284.
  • Herzog H, Darby K, Ball H, Hort Y, Beck-Sickinger A, Shine J (May 1997). "Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation". Genomics. 41 (3): 315–9. doi:10.1006/geno.1997.4684. PMID 9169127.
  • Nichol KA, Morey A, Couzens MH, Shine J, Herzog H, Cunningham AM (Dec 1999). "Conservation of expression of neuropeptide Y5 receptor between human and rat hypothalamus and limbic regions suggests an integral role in central neuroendocrine control". The Journal of Neuroscience. 19 (23): 10295–304. PMID 10575027.
  • Rodriguez M, Audinot V, Dromaint S, Macia C, Lamamy V, Beauverger P, Rique H, Imbert J, Nicolas JP, Boutin JA, Galizzi JP (Feb 2003). "Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform". The Biochemical Journal. 369 (Pt 3): 667–73. doi:10.1042/BJ20020739. PMC 1223119. PMID 12398768.
  • Berglund MM, Schober DA, Statnick MA, McDonald PH, Gehlert DR (Jul 2003). "The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction". The Journal of Pharmacology and Experimental Therapeutics. 306 (1): 147–56. doi:10.1124/jpet.103.051227. PMID 12665544.
  • Beauverger P, Rodriguez M, Nicolas JP, Audinot V, Lamamy V, Dromaint S, Nagel N, Macia C, Léopold O, Galizzi JP, Caignard DH, Aldana I, Monge A, Chomarat P, Boutin JA (Apr 2005). "Functional characterization of human neuropeptide Y receptor subtype five specific antagonists using a luciferase reporter gene assay". Cellular Signalling. 17 (4): 489–96. doi:10.1016/j.cellsig.2004.09.006. PMID 15601626.
  • Movafagh S, Hobson JP, Spiegel S, Kleinman HK, Zukowska Z (Sep 2006). "Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors". FASEB Journal. 20 (11): 1924–6. doi:10.1096/fj.05-4770fje. PMID 16891622.
  • Coletta DK, Schneider J, Stern MP, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP (Apr 2007). "Association of neuropeptide Y receptor Y5 polymorphisms with dyslipidemia in Mexican Americans". Obesity. 15 (4): 809–15. doi:10.1038/oby.2007.610. PMID 17426313.

External links


Retrieved from "https://www.wikidoc.org/index.php?title=Neuropeptide_Y_receptor_Y5&oldid=1413720"