CD276

CD276 molecule
Identifiers
Symbols	CD276 ; B7-H3; B7H3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 11892
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

CD276 (Cluster of Differentiation 276) is a human protein encoded by the CD276 gene.

Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558).[supplied by OMIM]

See also

• Cluster of differentiation

Further reading

• Chapoval AI, Ni J, Lau JS; et al. (2001). "B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production". Nat. Immunol. 2 (3): 269–74. doi:10.1038/85339. PMID 11224528.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sun M, Richards S, Prasad DV; et al. (2002). "Characterization of mouse and human B7-H3 genes". J. Immunol. 168 (12): 6294–7. PMID 12055244.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ling V, Wu PW, Spaulding V; et al. (2004). "Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss". Genomics. 82 (3): 365–77. PMID 12906861.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Steinberger P, Majdic O, Derdak SV; et al. (2004). "Molecular characterization of human 4Ig-B7-H3, a member of the B7 family with four Ig-like domains". J. Immunol. 172 (4): 2352–9. PMID 14764704.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang GB, Chen YJ, Shi Q; et al. (2005). "Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro". Acta Biochim. Biophys. Sin. (Shanghai). 36 (6): 430–6. PMID 15188059.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Castriconi R, Dondero A, Augugliaro R; et al. (2004). "Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis". Proc. Natl. Acad. Sci. U.S.A. 101 (34): 12640–5. doi:10.1073/pnas.0405025101. PMID 15314238.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang L, Fraser CC, Kikly K; et al. (2005). "B7-H3 promotes acute and chronic allograft rejection". Eur. J. Immunol. 35 (2): 428–38. doi:10.1002/eji.200425518. PMID 15682454.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim J, Myers AC, Chen L; et al. (2005). "Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells". Am. J. Respir. Cell Mol. Biol. 33 (3): 280–9. doi:10.1165/rcmb.2004-0129OC. PMID 15961727.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Petroff MG, Kharatyan E, Torry DS, Holets L (2005). "The immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placenta". Am. J. Pathol. 167 (2): 465–73. PMID 16049332.CS1 maint: Multiple names: authors list (link)
• Zhang GB, Dong QM, Xu Y; et al. "B7-H3: Another Molecule Marker for Mo-DCs?". Cell. Mol. Immunol. 2 (4): 307–11. PMID 16274630.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sakthivel P, Wang X, Gharizadeh B; et al. (2007). "Single-nucleotide polymorphisms in the B7H3 gene are not associated with human autoimmune myasthenia gravis". J. Genet. 85 (3): 217–20. PMID 17406098.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• CD276+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)