CD109: Difference between revisions

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Latest revision as of 02:25, 27 October 2017

CD109 (Cluster of Differentiation 109) is a human gene.^[1]

CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002).[supplied by OMIM]^[1]

References

↑ ^1.0 ^1.1 "Entrez Gene: CD109 CD109 molecule".

Lucas GF, Metcalfe P (2000). "Platelet and granulocyte glycoprotein polymorphisms". Transfusion medicine (Oxford, England). 10 (3): 157–74. doi:10.1046/j.1365-3148.2000.00250.x. PMID 10972910.
Sutherland DR, Yeo E, Ryan A, et al. (1991). "Identification of a cell-surface antigen associated with activated T lymphoblasts and activated platelets". Blood. 77 (1): 84–93. PMID 1984805.
Kelton JG, Smith JW, Horsewood P, et al. (1990). "Gova/b alloantigen system on human platelets". Blood. 75 (11): 2172–6. PMID 2346781.
Lin M, Sutherland DR, Horsfall W, et al. (2002). "Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins". Blood. 99 (5): 1683–91. doi:10.1182/blood.V99.5.1683. PMID 11861284.
Schuh AC, Watkins NA, Nguyen Q, et al. (2002). "A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens". Blood. 99 (5): 1692–8. doi:10.1182/blood.V99.5.1692. PMID 11861285.
Giesert C, Marxer A, Sutherland DR, et al. (2003). "Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets". Ann. N. Y. Acad. Sci. 996: 227–30. doi:10.1111/j.1749-6632.2003.tb03250.x. PMID 12799300.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Solomon KR, Sharma P, Chan M, et al. (2004). "CD109 represents a novel branch of the alpha2-macroglobulin/complement gene family". Gene. 327 (2): 171–83. doi:10.1016/j.gene.2003.11.025. PMID 14980714.
Zhang JM, Hashimoto M, Kawai K, et al. (2005). "CD109 expression in squamous cell carcinoma of the uterine cervix". Pathol. Int. 55 (4): 165–9. doi:10.1111/j.1440-1827.2005.01807.x. PMID 15826242.
Lewandrowski U, Moebius J, Walter U, Sickmann A (2006). "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach". Mol. Cell. Proteomics. 5 (2): 226–33. doi:10.1074/mcp.M500324-MCP200. PMID 16263699.
Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human Plasma N-Glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.
Finnson KW, Tam BY, Liu K, et al. (2006). "Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes". FASEB J. 20 (9): 1525–7. doi:10.1096/fj.05-5229fje. PMID 16754747.
Sjöblom T, Jones S, Wood LD, et al. (2006). "The consensus coding sequences of human breast and colorectal cancers". Science. 314 (5797): 268–74. doi:10.1126/science.1133427. PMID 16959974.
Hasegawa M, Hagiwara S, Sato T, et al. (2007). "CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells". Pathol. Int. 57 (5): 245–50. doi:10.1111/j.1440-1827.2007.02097.x. PMID 17493171.

External links

CD109+Antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
Human CD109 genome location and CD109 gene details page in the UCSC Genome Browser.

Stub icon

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[entrez-1] 1.0 ^1.1 "Entrez Gene: CD109 CD109 molecule".

[1]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Underlinked|date=May 2016}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''CD109''' ('''C'''luster of '''D'''ifferentiation '''109''') is a human [[gene]].<ref name="entrez"/>
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = CD109 molecule
- | HGNCid = 21685
- | Symbol = CD109
- | AltSymbols =; CPAMD7; DKFZp762L1111; FLJ38569; FLJ41966; RP11-525G3.1
- | OMIM = 608859
- | ECnumber =
- | Homologene = 25183
- | MGIid = 2445221
- | GeneAtlas_image1 = PBB_GE_CD109_gnf1h04600_at_tn.png
- | GeneAtlas_image2 = PBB_GE_CD109_gnf1h06370_at_tn.png
- | GeneAtlas_image3 = PBB_GE_CD109_gnf1h07791_at_tn.png
- | Function = {{GNF_GO|id=GO:0004867 |text = serine-type endopeptidase inhibitor activity}} {{GNF_GO|id=GO:0017114 |text = wide-spectrum protease inhibitor activity}} {{GNF_GO|id=GO:0048503 |text = GPI anchor binding}}
- | Component = {{GNF_GO|id=GO:0016020 |text = membrane}}
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 135228
-    | Hs_Ensembl = ENSG00000156535
-    | Hs_RefseqProtein = NP_598000
-    | Hs_RefseqmRNA = NM_133493
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 6
-    | Hs_GenLoc_start = 74462548
-    | Hs_GenLoc_end = 74591509
-    | Hs_Uniprot = Q6YHK3
-    | Mm_EntrezGene = 235505
-    | Mm_Ensembl = ENSMUSG00000046186
-    | Mm_RefseqmRNA = XM_985933
-    | Mm_RefseqProtein = XP_991027
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 9
-    | Mm_GenLoc_start = 78401461
-    | Mm_GenLoc_end = 78501940
-    | Mm_Uniprot = Q8R422
-  }}
-}}
-'''CD109''' ('''C'''luster of '''D'''ifferentiation '''109''') is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CD109 CD109 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=135228| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: CD109 CD109 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=135228| accessdate = }}</ref>
+| summary_text = CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: CD109 CD109 molecule| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=135228| accessdate = }}</ref>
 }}
@@ Line 60: / Line 13: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 66: / Line 19: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Lucas GF, Metcalfe P |title=Platelet and granulocyte glycoprotein polymorphisms. |journal=Transfusion medicine (Oxford, England) |volume=10 |issue= 3 |pages= 157-74 |year= 2000 |pmid= 10972910 |doi=  }}
+*{{cite journal  | vauthors=Lucas GF, Metcalfe P |title=Platelet and granulocyte glycoprotein polymorphisms. |journal=Transfusion medicine (Oxford, England) |volume=10 |issue= 3 |pages= 157–74 |year= 2000 |pmid= 10972910 |doi=  10.1046/j.1365-3148.2000.00250.x}}
-*{{cite journal  | author=Sutherland DR, Yeo E, Ryan A, ''et al.'' |title=Identification of a cell-surface antigen associated with activated T lymphoblasts and activated platelets. |journal=Blood |volume=77 |issue= 1 |pages= 84-93 |year= 1991 |pmid= 1984805 |doi=  }}
+*{{cite journal  | vauthors=Sutherland DR, Yeo E, Ryan A |title=Identification of a cell-surface antigen associated with activated T lymphoblasts and activated platelets. |journal=Blood |volume=77 |issue= 1 |pages= 84–93 |year= 1991 |pmid= 1984805 |doi=  |display-authors=etal}}
-*{{cite journal  | author=Kelton JG, Smith JW, Horsewood P, ''et al.'' |title=Gova/b alloantigen system on human platelets. |journal=Blood |volume=75 |issue= 11 |pages= 2172-6 |year= 1990 |pmid= 2346781 |doi=  }}
+*{{cite journal  | vauthors=Kelton JG, Smith JW, Horsewood P |title=Gova/b alloantigen system on human platelets. |journal=Blood |volume=75 |issue= 11 |pages= 2172–6 |year= 1990 |pmid= 2346781 |doi=  |display-authors=etal}}
-*{{cite journal  | author=Lin M, Sutherland DR, Horsfall W, ''et al.'' |title=Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins. |journal=Blood |volume=99 |issue= 5 |pages= 1683-91 |year= 2002 |pmid= 11861284 |doi=  }}
+*{{cite journal  | vauthors=Lin M, Sutherland DR, Horsfall W |title=Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins. |journal=Blood |volume=99 |issue= 5 |pages= 1683–91 |year= 2002 |pmid= 11861284 |doi=10.1182/blood.V99.5.1683  |display-authors=etal}}
-*{{cite journal  | author=Schuh AC, Watkins NA, Nguyen Q, ''et al.'' |title=A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens. |journal=Blood |volume=99 |issue= 5 |pages= 1692-8 |year= 2002 |pmid= 11861285 |doi=  }}
+*{{cite journal  | vauthors=Schuh AC, Watkins NA, Nguyen Q |title=A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens. |journal=Blood |volume=99 |issue= 5 |pages= 1692–8 |year= 2002 |pmid= 11861285 |doi=10.1182/blood.V99.5.1692  |display-authors=etal}}
-*{{cite journal  | author=Giesert C, Marxer A, Sutherland DR, ''et al.'' |title=Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets. |journal=Ann. N. Y. Acad. Sci. |volume=996 |issue=  |pages= 227-30 |year= 2003 |pmid= 12799300 |doi=  }}
+*{{cite journal  | vauthors=Giesert C, Marxer A, Sutherland DR |title=Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets. |journal=Ann. N. Y. Acad. Sci. |volume=996 |issue=  |pages= 227–30 |year= 2003 |pmid= 12799300 |doi=10.1111/j.1749-6632.2003.tb03250.x  |display-authors=etal}}
-*{{cite journal  | author=Mungall AJ, Palmer SA, Sims SK, ''et al.'' |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
+*{{cite journal  | vauthors=Mungall AJ, Palmer SA, Sims SK |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |display-authors=etal}}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
-*{{cite journal  | author=Solomon KR, Sharma P, Chan M, ''et al.'' |title=CD109 represents a novel branch of the alpha2-macroglobulin/complement gene family. |journal=Gene |volume=327 |issue= 2 |pages= 171-83 |year= 2004 |pmid= 14980714 |doi= 10.1016/j.gene.2003.11.025 }}
+*{{cite journal  | vauthors=Solomon KR, Sharma P, Chan M |title=CD109 represents a novel branch of the alpha2-macroglobulin/complement gene family. |journal=Gene |volume=327 |issue= 2 |pages= 171–83 |year= 2004 |pmid= 14980714 |doi= 10.1016/j.gene.2003.11.025 |display-authors=etal}}
-*{{cite journal  | author=Zhang JM, Hashimoto M, Kawai K, ''et al.'' |title=CD109 expression in squamous cell carcinoma of the uterine cervix. |journal=Pathol. Int. |volume=55 |issue= 4 |pages= 165-9 |year= 2005 |pmid= 15826242 |doi= 10.1111/j.1440-1827.2005.01807.x }}
+*{{cite journal  | vauthors=Zhang JM, Hashimoto M, Kawai K |title=CD109 expression in squamous cell carcinoma of the uterine cervix. |journal=Pathol. Int. |volume=55 |issue= 4 |pages= 165–9 |year= 2005 |pmid= 15826242 |doi= 10.1111/j.1440-1827.2005.01807.x |display-authors=etal}}
-*{{cite journal  | author=Lewandrowski U, Moebius J, Walter U, Sickmann A |title=Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. |journal=Mol. Cell Proteomics |volume=5 |issue= 2 |pages= 226-33 |year= 2006 |pmid= 16263699 |doi= 10.1074/mcp.M500324-MCP200 }}
+*{{cite journal  | vauthors=Lewandrowski U, Moebius J, Walter U, Sickmann A |title=Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. |journal=Mol. Cell. Proteomics |volume=5 |issue= 2 |pages= 226–33 |year= 2006 |pmid= 16263699 |doi= 10.1074/mcp.M500324-MCP200 }}
-*{{cite journal  | author=Liu T, Qian WJ, Gritsenko MA, ''et al.'' |title=Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070-80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065 }}
+*{{cite journal  | vauthors=Liu T, Qian WJ, Gritsenko MA |title=Human Plasma N-Glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070–80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065  | pmc=1850943 |display-authors=etal}}
-*{{cite journal  | author=Finnson KW, Tam BY, Liu K, ''et al.'' |title=Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes. |journal=FASEB J. |volume=20 |issue= 9 |pages= 1525-7 |year= 2006 |pmid= 16754747 |doi= 10.1096/fj.05-5229fje }}
+*{{cite journal  | vauthors=Finnson KW, Tam BY, Liu K |title=Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes |journal=FASEB J. |volume=20 |issue= 9 |pages= 1525–7 |year= 2006 |pmid= 16754747 |doi= 10.1096/fj.05-5229fje |display-authors=etal}}
-*{{cite journal  | author=Sjöblom T, Jones S, Wood LD, ''et al.'' |title=The consensus coding sequences of human breast and colorectal cancers. |journal=Science |volume=314 |issue= 5797 |pages= 268-74 |year= 2006 |pmid= 16959974 |doi= 10.1126/science.1133427 }}
+*{{cite journal  | vauthors=Sjöblom T, Jones S, Wood LD |title=The consensus coding sequences of human breast and colorectal cancers |journal=Science |volume=314 |issue= 5797 |pages= 268–74 |year= 2006 |pmid= 16959974 |doi= 10.1126/science.1133427 |display-authors=etal}}
-*{{cite journal  | author=Hasegawa M, Hagiwara S, Sato T, ''et al.'' |title=CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells. |journal=Pathol. Int. |volume=57 |issue= 5 |pages= 245-50 |year= 2007 |pmid= 17493171 |doi= 10.1111/j.1440-1827.2007.02097.x }}
+*{{cite journal  | vauthors=Hasegawa M, Hagiwara S, Sato T |title=CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells |journal=Pathol. Int. |volume=57 |issue= 5 |pages= 245–50 |year= 2007 |pmid= 17493171 |doi= 10.1111/j.1440-1827.2007.02097.x |display-authors=etal}}
 }}
 {{refend}}
@@ Line 86: / Line 39: @@
 ==External links==
 * {{MeshName|CD109+Antigen}}
+* {{UCSC gene info|CD109}}
-{{membrane-protein-stub}}
 {{Clusters of differentiation}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 [[Category:Clusters of differentiation]]
-{{WikiDoc Sources}}
+{{membrane-protein-stub}}

v t e Proteins: clusters of differentiation (see also list of human clusters of differentiation)
1-50	CD1 a-c 1A 1D 1E CD2 CD3 γ δ ε CD4 CD5 CD6 CD7 CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50
51-100	CD51 CD52 CD53 CD54 CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85 a d e h j k CD86 CD87 CD88 CD89 CD90 CD91 - CD92 CD93 CD94 CD95 CD96 CD97 CD98 CD99 CD100
101-150	CD101 CD102 CD103 CD104 CD105 CD106 CD107 a b CD108 CD109 CD110 CD111 CD112 CD113 CD114 CD115 CD116 CD117 CD118 CD119 CD120 a b CD121 a b CD122 CD123 CD124 CD125 CD126 CD127 CD129 CD130 CD131 CD132 CD133 CD134 CD135 CD136 CD137 CD138 CD140b CD141 CD142 CD143 CD144 CD146 CD147 CD148 CD150
151-200	CD151 CD152 CD153 CD154 CD155 CD156 a b c CD157 CD158 (a d e i k) CD159 a c CD160 CD161 CD162 CD163 CD164 CD166 CD167 a b CD168 CD169 CD170 CD171 CD172 a b g CD174 CD177 CD178 CD179 a b CD180 CD181 CD182 CD183 CD184 CD185 CD186 CD191 CD192 CD193 CD194 CD195 CD196 CD197 CDw198 CDw199 CD200
201-250	CD201 CD202b CD204 CD205 CD206 CD207 CD208 CD209 CDw210 a b CD212 CD213a 1 2 CD217 CD218 (a b) CD220 CD221 CD222 CD223 CD224 CD225 CD226 CD227 CD228 CD229 CD230 CD233 CD234 CD235 a b CD236 CD238 CD239 CD240CE CD240D CD241 CD243 CD244 CD246 CD247 - CD248 CD249
251-300	CD252 CD253 CD254 CD256 CD257 CD258 CD261 CD262 CD263 CD264 CD265 CD266 CD267 CD268 CD269 CD271 CD272 CD273 CD274 CD275 CD276 CD278 CD279 CD280 CD281 CD282 CD283 CD284 CD286 CD288 CD289 CD290 CD292 CDw293 CD294 CD295 CD297 CD298 CD299
301-350	CD300A CD301 CD302 CD303 CD304 CD305 CD306 CD307 CD309 CD312 CD314 CD315 CD316 CD317 CD318 CD320 CD321 CD322 CD324 CD325 CD326 CD328 CD329 CD331 CD332 CD333 CD334 CD335 CD336 CD337 CD338 CD339 CD340 CD344 CD349 CD350

CD109: Difference between revisions

Latest revision as of 02:25, 27 October 2017

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See also

References

Further reading

External links

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