Cardiac disease in pregnancy and arrhythmias: Difference between revisions

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==Overview==
==Overview==
Although underlying reasons remain unclear, if a woman has a prior history of arrhythmias, they may increase in frequency during pregnancy.  Unfortunately durgs that are effective a significant increase of the incidence and severity of [[cardiac arrhythmias]] in pregnancy (particularly [[atrial arrhythmias|atrial]] and [[ventricular premature beat]]s without an existing heart disease) have been reported in numerous articles, and these [[arrhythmia]]s are usually benign. <ref> Tawam M, Levine J, Mendelson M, Goldberger J, Dyer A, Kadish A. Effect of pregnancy on paroxysmal supraventricular tachycardia. Am J Cardiol 1993; 72: 838-40.</ref> <ref>Brodsky M, Doria R, Allen B, Sato D, Thomas G, Sada M. New-onset ventricular tachycardia during pregnancy. Am Heart J 1992; 123: 933-41.</ref> <ref name="Chow">Chow T, Galvin J, McGovern B. Antiarrhythmic drug therapy in pregnancy and lactation. Am J Cardiol 1998; 82 (4A): 58I - 62I. </ref>   
Although underlying reasons remain unclear, if a woman has a prior history of [[arrhythmias]], the risk of recurrent arrhythmias may increase during pregnancy.<ref> Tawam M, Levine J, Mendelson M, Goldberger J, Dyer A, Kadish A. Effect of pregnancy on paroxysmal supraventricular tachycardia. Am J Cardiol 1993; 72: 838-40.</ref> <ref>Brodsky M, Doria R, Allen B, Sato D, Thomas G, Sada M. New-onset ventricular tachycardia during pregnancy. Am Heart J 1992; 123: 933-41.</ref> <ref name="Chow">Chow T, Galvin J, McGovern B. Antiarrhythmic drug therapy in pregnancy and lactation. Am J Cardiol 1998; 82 (4A): 58I - 62I. </ref>  Unfortunately drugs that are effective in the management of arrhythmias such as amiodarone can present a hazard to the fetus during pregnancy.
 
It is necessary to check if a pregnant woman takes any over the counter drug which causes palpitation or premature beats (e.g., [[pseudoephedrine]]). <ref name="Chow">Chow T, Galvin J, McGovern B. Antiarrhythmic drug therapy in pregnancy and lactation. Am J Cardiol 1998; 82 (4A): 58I - 62I. </ref> 


==Anti-arrhythmic Drugs to Avoid During the Pregnancy==
==Anti-arrhythmic Drugs to Avoid During the Pregnancy==

Revision as of 12:00, 11 October 2012

Cardiac disease in pregnancy Microchapters

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III. Cardiomyopathy:
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IV. Cardiac diseases that may develop During Pregnancy:
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Although underlying reasons remain unclear, if a woman has a prior history of arrhythmias, the risk of recurrent arrhythmias may increase during pregnancy.[1] [2] [3] Unfortunately drugs that are effective in the management of arrhythmias such as amiodarone can present a hazard to the fetus during pregnancy.

Anti-arrhythmic Drugs to Avoid During the Pregnancy

Anti-arrhythmic Drugs to Avoid During Lactation

  • Secreted in breast milk
  • It becomes concentrated in breast milk. Infants receive much larger doses.
  • Neonatal bradycardia
  • Neonatal hypoglycemia

Related Chapters

References

  1. Tawam M, Levine J, Mendelson M, Goldberger J, Dyer A, Kadish A. Effect of pregnancy on paroxysmal supraventricular tachycardia. Am J Cardiol 1993; 72: 838-40.
  2. Brodsky M, Doria R, Allen B, Sato D, Thomas G, Sada M. New-onset ventricular tachycardia during pregnancy. Am Heart J 1992; 123: 933-41.
  3. Chow T, Galvin J, McGovern B. Antiarrhythmic drug therapy in pregnancy and lactation. Am J Cardiol 1998; 82 (4A): 58I - 62I.
  4. 4.0 4.1 4.2 Onuigbo M, Alikhan M. Over-the-counter sympathomimetics: a risk factor for cardiac arrhythmias in pregnancy. South Med J 1998; 91: 1153-5.
  5. Eliahou HE, Silverberg DS, Reisin E, Romem I, Mashiach S, Serr DM. Propranolol for the treatment of hypertension in pregnancy. Br J Obstet Gynaecol 1978;85:431-6.
  6. Lydakis C, Lip GY, Beevers M, Beevers DG. Atenolol and fetal growth in pregnancies complicated by hypertension. Am J Hypertens 1999; 12:541-7.


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