The EKG in the patient treated with calcium channel blockers
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. 
- In patients with sinus node disease, verapamil and diltiazem may cause severe bradycardia and even sinus arrest.
- Effect on rate depends on the balance between the effect on the conduction system and a reflex increase in the heart rate due to vasodilation.
- Diltiazem and verapamil may prolong the PR interval, nifedipine has no effect.
- No effect on the QRS or the QTc