MRGPRX2: Difference between revisions

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'''Mas-related G-protein coupled receptor member X2''' is a [[protein]] that in humans is encoded by the ''MRGPRX2'' [[gene]].<ref name="pmid11551509">{{cite journal |vauthors=Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ | title = A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons | journal = Cell | volume = 106 | issue = 5 | pages = 619–632 |date=Sep 2001 | pmid = 11551509 | pmc =  | doi =10.1016/S0092-8674(01)00483-4  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MRGPRX2 MAS-related GPR, member X2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117194| accessdate = }}</ref>
'''Mas-related G-protein coupled receptor member X2''' is a [[protein]] that in humans is encoded by the ''MRGPRX2'' [[gene]].<ref name="pmid11551509">{{cite journal |vauthors=Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ | title = A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons | journal = Cell | volume = 106 | issue = 5 | pages = 619–632 |date=Sep 2001 | pmid = 11551509 | pmc =  | doi =10.1016/S0092-8674(01)00483-4  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MRGPRX2 MAS-related GPR, member X2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117194| accessdate = }}</ref>
Agonists are gyrase inhibitors like ciprofloxacine and non-steroidal neuromuscular blocking agents like atracurium as well as vancomycin. Activation of MRGPRX2 leads to mast cell degranulation with subsequent pseudo-allergic reactions.
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[[Category:G protein coupled receptors]]
[[Category:G protein-coupled receptors]]
 
 
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Latest revision as of 18:01, 24 September 2018

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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Wikidata
View/Edit Human

Mas-related G-protein coupled receptor member X2 is a protein that in humans is encoded by the MRGPRX2 gene.[1][2] Agonists are gyrase inhibitors like ciprofloxacine and non-steroidal neuromuscular blocking agents like atracurium as well as vancomycin. Activation of MRGPRX2 leads to mast cell degranulation with subsequent pseudo-allergic reactions.


See also

References

  1. ↑ Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell. 106 (5): 619–632. doi:10.1016/S0092-8674(01)00483-4. PMID 11551509.
  2. ↑ "Entrez Gene: MRGPRX2 MAS-related GPR, member X2".

Further reading

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