GPR61: Difference between revisions

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{{Infobox_gene}}
 
'''Probable G-protein coupled receptor 61''' is a [[protein]] that in humans is encoded by the ''GPR61'' [[gene]].<ref name="pmid11165367">{{cite journal |vauthors=Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF | title = Identification of four novel human G protein-coupled receptors expressed in the brain | journal = Brain Res Mol Brain Res | volume = 86 | issue = 1–2 | pages = 13–22 |date=Feb 2001 | pmid = 11165367 | pmc =  | doi =10.1016/S0169-328X(00)00242-4 }}</ref><ref name="pmid11690637">{{cite journal |vauthors=Cikos S, Gregor P, Koppel J | title = Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain | journal = Biochim Biophys Acta | volume = 1521 | issue = 1–3 | pages = 66–72 |date=Nov 2001 | pmid = 11690637 | pmc =  | doi 10.1016/s0167-4781(01)00289-5}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPR61 G protein-coupled receptor 61| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83873| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = G protein-coupled receptor 61
| HGNCid = 13300
| Symbol = GPR61
| AltSymbols =; BALGR; GPCR3
| OMIM = 606916
| ECnumber =
| Homologene = 12910
| MGIid = 2441719
  | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}}{{GNF_GO|id=GO:0004872 |text = receptor activity}}
  | Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0008150 |text = biological_process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 83873
    | Hs_Ensembl = ENSG00000156097
    | Hs_RefseqProtein = NP_114142
    | Hs_RefseqmRNA = NM_031936
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 109884032
    | Hs_GenLoc_end = 109892551
    | Hs_Uniprot = Q9BZJ8
    | Mm_EntrezGene = 229714
    | Mm_Ensembl = ENSMUSG00000046793
    | Mm_RefseqmRNA = NM_175470
    | Mm_RefseqProtein = NP_780679
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 108276377
    | Mm_GenLoc_end = 108282938
    | Mm_Uniprot = Q3UZR6
  }}
}}
'''G protein-coupled receptor 61''', also known as '''GPR61''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR61 G protein-coupled receptor 61| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83873| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.<ref name="entrez">{{cite web | title = Entrez Gene: GPR61 G protein-coupled receptor 61| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83873| accessdate = }}</ref>
| summary_text = This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.<ref name="entrez" />
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |display-authors=3 |author1=Gregory SG |author2=Barlow KF |author3=McLay KE |name-list-format=vanc |last4=Kaul |first4=R |last5=Swarbreck |first5=D |last6=Dunham |first6=A |last7=Scott |first7=CE |last8=Howe |first8=KL |last9=Woodfine |first9=K }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |display-authors=3 |author1=Kimura K |author2=Wakamatsu A |author3=Suzuki Y |name-list-format=vanc |last4=Ota |first4=T |last5=Nishikawa |first5=T |last6=Yamashita |first6=R |last7=Yamamoto |first7=J |last8=Sekine |first8=M |last9=Tsuritani |first9=K |pmc=1356129 }}
*{{cite journal | author=Conner AC, Hay DL, Simms J, ''et al.'' |title=A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors. |journal=Mol. Pharmacol. |volume=67 |issue= 1 |pages= 20-31 |year= 2005 |pmid= 15615699 |doi= 10.1124/mol.67.1. }}
*{{cite journal |title=A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors |journal=Mol. Pharmacol. |volume=67 |issue= 1 |pages= 20–31 |year= 2005 |pmid= 15615699 |doi= 10.1124/mol.67.1 |display-authors=3 |author1=Conner AC |author2=Hay DL |author3=Simms J |name-list-format=vanc |last4=Howitt |first4=SG |last5=Schindler |first5=M |last6=Smith |first6=DM |last7=Wheatley |first7=M |last8=Poyner |first8=DR }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |display-authors=3 |author1=Gerhard DS |author2=Wagner L |author3=Feingold EA |name-list-format=vanc |last4=Shenmen |first4=CM |last5=Grouse |first5=LH |last6=Schuler |first6=G |last7=Klein |first7=SL |last8=Old |first8=S |last9=Rasooly |first9=R |pmc=528928 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |display-authors=3 |author1=Strausberg RL |author2=Feingold EA |author3=Grouse LH |name-list-format=vanc |last4=Derge |first4=JG |last5=Klausner |first5=RD |last6=Collins |first6=FS |last7=Wagner |first7=L |last8=Shenmen |first8=CM |last9=Schuler |first9=GD |pmc=139241 }}
*{{cite journal  | author=Takeda S, Kadowaki S, Haga T, ''et al.'' |title=Identification of G protein-coupled receptor genes from the human genome sequence. |journal=FEBS Lett. |volume=520 |issue= 1-3 |pages= 97-101 |year= 2002 |pmid= 12044878 |doi= }}
*{{cite journal |title=Identification of G protein-coupled receptor genes from the human genome sequence |journal=FEBS Lett. |volume=520 |issue= 1–3 |pages= 97–101 |year= 2002 |pmid= 12044878 |doi=10.1016/S0014-5793(02)02775-8 |display-authors=3 |author1=Takeda S |author2=Kadowaki S |author3=Haga T |name-list-format=vanc |last4=Takaesu |first4=H |last5=Mitaku |first5=S }}
*{{cite journal | author=Cikos S, Gregor P, Koppel J |title=Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain. |journal=Biochim. Biophys. Acta |volume=1521 |issue= 1-3 |pages= 66-72 |year= 2001 |pmid= 11690637 |doi= }}
*{{cite journal  | author=Lee DK, George SR, Cheng R, ''et al.'' |title=Identification of four novel human G protein-coupled receptors expressed in the brain. |journal=Brain Res. Mol. Brain Res. |volume=86 |issue= 1-2 |pages= 13-22 |year= 2001 |pmid= 11165367 |doi=  }}
}}
}}
{{refend}}
{{refend}}
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{{NLM content}}
{{NLM content}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]


{{WH}}
 
{{WS}}
{{transmembranereceptor-stub}}

Revision as of 09:01, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.[1][2][3]

This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.[3]

References

  1. Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
  2. Cikos S, Gregor P, Koppel J (Nov 2001). "Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain". Biochim Biophys Acta. 1521 (1–3): 66–72. doi:10.1016/s0167-4781(01)00289-5. PMID 11690637.
  3. 3.0 3.1 "Entrez Gene: GPR61 G protein-coupled receptor 61".

Further reading

See also

This article incorporates text from the United States National Library of Medicine, which is in the public domain.