EPHA6: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
imported>Jmertel23
m (removed "underlinked" tag)
 
(One intermediate revision by one other user not shown)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{Infobox_gene}}
{{GNF_Protein_box
'''Ephrin type-A receptor 6''' is a [[protein]] that in humans is encoded by the ''EPHA6'' [[gene]].<ref name="pmid12471243">{{cite journal | vauthors = Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S | title = The protein kinase complement of the human genome | journal = Science | volume = 298 | issue = 5600 | pages = 1912–34 |date=Dec 2002 | pmid = 12471243 | pmc =  | doi = 10.1126/science.1075762 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPHA6 EPH receptor A6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=285220| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = EPH receptor A6
| HGNCid = 19296
| Symbol = EPHA6
| AltSymbols =; DKFZp434C1418; EPA6; FLJ35246; PRO57066
| OMIM = 
| ECnumber = 
| Homologene = 56396
| MGIid = 108034
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0004713 |text = protein-tyrosine kinase activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005003 |text = ephrin receptor activity}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016740 |text = transferase activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006468 |text = protein amino acid phosphorylation}} {{GNF_GO|id=GO:0007169 |text = transmembrane receptor protein tyrosine kinase signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 285220
    | Hs_Ensembl = ENSG00000080224
    | Hs_RefseqProtein = XP_001126591
    | Hs_RefseqmRNA = XM_001126591
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 98016311
    | Hs_GenLoc_end = 98950232
    | Hs_Uniprot = Q9UF33
    | Mm_EntrezGene = 13840
    | Mm_Ensembl = ENSMUSG00000055540
    | Mm_RefseqmRNA = NM_007938
    | Mm_RefseqProtein = NP_031964
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 59596276
    | Mm_GenLoc_end = 60547219
    | Mm_Uniprot = Q3V2Z8
  }}
}}
'''EPH receptor A6''', also known as '''EPHA6''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EPHA6 EPH receptor A6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=285220| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 54: Line 10:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Wilkinson DG |title=Eph receptors and ephrins: regulators of guidance and assembly. |journal=Int. Rev. Cytol. |volume=196 |issue=  |pages= 177-244 |year= 2000 |pmid= 10730216 |doi=  }}
*{{cite journal  | author=Wilkinson DG |title=Eph receptors and ephrins: regulators of guidance and assembly. |journal=Int. Rev. Cytol. |volume=196 |issue=  |pages= 177–244 |year= 2000 |pmid= 10730216 |doi=10.1016/S0074-7696(00)96005-4 }}
*{{cite journal  | author=Xu Q, Mellitzer G, Wilkinson DG |title=Roles of Eph receptors and ephrins in segmental patterning. |journal=Philos. Trans. R. Soc. Lond., B, Biol. Sci. |volume=355 |issue= 1399 |pages= 993-1002 |year= 2001 |pmid= 11128993 |doi= 10.1098/rstb.2000.0635 }}
*{{cite journal  | vauthors=Xu Q, Mellitzer G, Wilkinson DG |title=Roles of Eph receptors and ephrins in segmental patterning. |journal=Philos. Trans. R. Soc. Lond. B Biol. Sci. |volume=355 |issue= 1399 |pages= 993–1002 |year= 2001 |pmid= 11128993 |doi= 10.1098/rstb.2000.0635  | pmc=1692797 }}
*{{cite journal | author=Manning G, Whyte DB, Martinez R, ''et al.'' |title=The protein kinase complement of the human genome. |journal=Science |volume=298 |issue= 5600 |pages= 1912-34 |year= 2003 |pmid= 12471243 |doi= 10.1126/science.1075762 }}
*{{cite journal  | vauthors=Nakamoto T, Kain KH, Ginsberg MH |title=Neurobiology: New connections between integrins and axon guidance. |journal=Curr. Biol. |volume=14 |issue= 3 |pages= R121–3 |year= 2004 |pmid= 14986683 |doi=  10.1016/j.cub.2004.01.020}}
*{{cite journal  | author=Nakamoto T, Kain KH, Ginsberg MH |title=Neurobiology: New connections between integrins and axon guidance. |journal=Curr. Biol. |volume=14 |issue= 3 |pages= R121-3 |year= 2004 |pmid= 14986683 |doi=  }}
*{{cite journal  | vauthors=Yamaguchi Y, Pasquale EB |title=Eph receptors in the adult brain. |journal=Curr. Opin. Neurobiol. |volume=14 |issue= 3 |pages= 288–96 |year= 2004 |pmid= 15194108 |doi= 10.1016/j.conb.2004.04.003 }}
*{{cite journal  | author=Yamaguchi Y, Pasquale EB |title=Eph receptors in the adult brain. |journal=Curr. Opin. Neurobiol. |volume=14 |issue= 3 |pages= 288-96 |year= 2004 |pmid= 15194108 |doi= 10.1016/j.conb.2004.04.003 }}
*{{cite journal  | vauthors=Murai KK, Pasquale EB |title=Eph receptors, ephrins, and synaptic function. |journal=The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry |volume=10 |issue= 4 |pages= 304–14 |year= 2004 |pmid= 15271258 |doi= 10.1177/1073858403262221 }}
*{{cite journal  | author=Murai KK, Pasquale EB |title=Eph receptors, ephrins, and synaptic function. |journal=The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry |volume=10 |issue= 4 |pages= 304-14 |year= 2004 |pmid= 15271258 |doi= 10.1177/1073858403262221 }}
*{{cite journal  | vauthors=Gale NW, Holland SJ, Valenzuela DM |title=Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. |journal=Neuron |volume=17 |issue= 1 |pages= 9–19 |year= 1996 |pmid= 8755474 |doi=10.1016/S0896-6273(00)80276-7 |display-authors=etal}}
*{{cite journal  | author=Gale NW, Holland SJ, Valenzuela DM, ''et al.'' |title=Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. |journal=Neuron |volume=17 |issue= 1 |pages= 9-19 |year= 1996 |pmid= 8755474 |doi=  }}
*{{cite journal  | vauthors=Aasheim HC, Munthe E, Funderud S |title=A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes. |journal=Blood |volume=95 |issue= 1 |pages= 221–30 |year= 2000 |pmid= 10607706 |doi=  |display-authors=etal}}
*{{cite journal  | author=Aasheim HC, Munthe E, Funderud S, ''et al.'' |title=A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes. |journal=Blood |volume=95 |issue= 1 |pages= 221-30 |year= 2000 |pmid= 10607706 |doi=  }}
*{{cite journal  | vauthors=Prevost N, Woulfe D, Tanaka T, Brass LF |title=Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 14 |pages= 9219–24 |year= 2002 |pmid= 12084815 |doi= 10.1073/pnas.142053899 | pmc=123121 }}
*{{cite journal  | author=Prevost N, Woulfe D, Tanaka T, Brass LF |title=Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 14 |pages= 9219-24 |year= 2002 |pmid= 12084815 |doi= 10.1073/pnas.142053899 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Clark HF, Gurney AL, Abaya E |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 |display-authors=etal}}
*{{cite journal  | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | vauthors=Hafner C, Schmitz G, Meyer S |title=Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers. |journal=Clin. Chem. |volume=50 |issue= 3 |pages= 490–9 |year= 2004 |pmid= 14726470 |doi= 10.1373/clinchem.2003.026849 |display-authors=etal}}
*{{cite journal  | author=Hafner C, Schmitz G, Meyer S, ''et al.'' |title=Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers. |journal=Clin. Chem. |volume=50 |issue= 3 |pages= 490-9 |year= 2004 |pmid= 14726470 |doi= 10.1373/clinchem.2003.026849 }}
*{{cite journal  | vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |display-authors=etal}}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{Tyrosine kinases}}
{{WikiDoc Sources}}
{{Enzymes}}
{{Growth factor receptor modulators}}
{{Portal bar|Molecular and Cellular Biology|border=no}}
 
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
[[Category:Tyrosine kinase receptors]]
 
 
{{gene-3-stub}}

Latest revision as of 17:34, 21 February 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ephrin type-A receptor 6 is a protein that in humans is encoded by the EPHA6 gene.[1][2]


References

  1. ↑ Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (Dec 2002). "The protein kinase complement of the human genome". Science. 298 (5600): 1912–34. doi:10.1126/science.1075762. PMID 12471243.
  2. ↑ "Entrez Gene: EPHA6 EPH receptor A6".

Further reading


Retrieved from "https://www.wikidoc.org/index.php?title=EPHA6&oldid=1532353"