Matuzumab

	WikiDoc Resources for Matuzumab
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Evidence Based Medicine
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Clinical Trials
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Guidelines / Policies / Govt
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Commentary
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Definitions
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Patient Resources / Community
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Healthcare Provider Resources
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Continuing Medical Education (CME)
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International
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Business
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Experimental / Informatics
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Overview

Matuzumab (formerly EMD 72000) is a humanized monoclonal antibody for the treatment of cancer. It binds to EGFR (epithelial growth factor receptor) with high affinity.

Developed by Merck Serono in cooperation with Takeda Pharmaceutical, it is currently undergoing phase II clinical trials for the treatment of colorectal, lung and stomach cancer. On August 29, 2007, Merck Serono announced that the preliminary results of the colorectal cancer study were less than promising, and that further trials for treating this type of cancer may be abandoned. The results of the lung and stomach cancer studies are expected in 2008.^[1]