Y box binding protein 1

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Y box binding protein 1
File:PBB Protein YBX1 image.jpg
PDB rendering based on 1h95.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols YBX1 ; BP-8; CSDA2; CSDB; DBPB; MDR-NF1; MGC104858; MGC110976; MGC117250; NSEP-1; NSEP1; YB-1; YB1
External IDs Template:OMIM5 HomoloGene: 88707
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Y box binding protein 1, officially known as YBX1, but commonly referred to as "YB-1" by researchers, is a human protein.[1] Current research is examining its involvement in cancer, and particularly in the metastasis of cancerous cells or prevention thereof.


References

  1. ↑ "Entrez Gene: YBX1 Y box binding protein 1".

Further reading

  • Kolluri R, Torrey TA, Kinniburgh AJ (1992). "A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif". Nucleic Acids Res. 20 (1): 111–6. PMID 1738588.
  • Kolluri R, Kinniburgh AJ (1991). "Full length cDNA sequence encoding a nuclease-sensitive element DNA binding protein". Nucleic Acids Res. 19 (17): 4771. PMID 1891370.
  • Sakura H, Maekawa T, Imamoto F; et al. (1989). "Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology". Gene. 73 (2): 499–507. PMID 2977358.
  • Didier DK, Schiffenbauer J, Woulfe SL; et al. (1988). "Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box". Proc. Natl. Acad. Sci. U.S.A. 85 (19): 7322–6. PMID 3174636.
  • Kudo S, Mattei MG, Fukuda M (1995). "Characterization of the gene for dbpA, a family member of the nucleic-acid-binding proteins containing a cold-shock domain". Eur. J. Biochem. 231 (1): 72–82. PMID 7628487.
  • Lloberas J, Maki RA, Celada A (1995). "Repression of major histocompatibility complex I-A beta gene expression by dbpA and dbpB (mYB-1) proteins". Mol. Cell. Biol. 15 (9): 5092–9. PMID 7651426.
  • Chen NN, Chang CF, Gallia GL; et al. (1995). "Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element". Proc. Natl. Acad. Sci. U.S.A. 92 (4): 1087–91. PMID 7862639.
  • Horwitz EM, Maloney KA, Ley TJ (1994). "A human protein containing a "cold shock" domain binds specifically to H-DNA upstream from the human gamma-globin genes". J. Biol. Chem. 269 (19): 14130–9. PMID 8188694.
  • Kashanchi F, Duvall JF, Dittmer J; et al. (1994). "Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expression". J. Virol. 68 (1): 561–5. PMID 8254772.
  • Makino Y, Ohga T, Toh S; et al. (1996). "Structural and functional analysis of the human Y-box binding protein (YB-1) gene promoter". Nucleic Acids Res. 24 (10): 1873–8. PMID 8657568.
  • Funke B, Zuleger B, Benavente R; et al. (1996). "The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins". Nucleic Acids Res. 24 (19): 3821–8. PMID 8871564.
  • Koike K, Uchiumi T, Ohga T; et al. (1998). "Nuclear translocation of the Y-box binding protein by ultraviolet irradiation". FEBS Lett. 417 (3): 390–4. PMID 9409758.
  • Toh S, Nakamura T, Ohga T; et al. (1998). "Genomic organization of the human Y-box protein (YB-1) gene". Gene. 206 (1): 93–7. PMID 9461420.
  • Sawaya BE, Khalili K, Amini S (1998). "Transcription of the human immunodeficiency virus type 1 (HIV-1) promoter in central nervous system cells: effect of YB-1 on expression of the HIV-1 long terminal repeat". J. Gen. Virol. 79 ( Pt 2): 239–46. PMID 9472608.
  • Mertens PR, Alfonso-Jaume MA, Steinmann K, Lovett DH (1999). "A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription". J. Biol. Chem. 273 (49): 32957–65. PMID 9830047.
  • Ise T, Nagatani G, Imamura T; et al. (1999). "Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen". Cancer Res. 59 (2): 342–6. PMID 9927044.
  • Safak M, Gallia GL, Khalili K (1999). "Reciprocal interaction between two cellular proteins, Puralpha and YB-1, modulates transcriptional activity of JCVCY in glial cells". Mol. Cell. Biol. 19 (4): 2712–23. PMID 10082537.
  • Kelm RJ, Cogan JG, Elder PK; et al. (1999). "Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter". J. Biol. Chem. 274 (20): 14238–45. PMID 10318844.
  • Safak M, Gallia GL, Ansari SA, Khalili K (1999). "Physical and functional interaction between the Y-box binding protein YB-1 and human polyomavirus JC virus large T antigen". J. Virol. 73 (12): 10146–57. PMID 10559330.
  • Ansari SA, Safak M, Gallia GL; et al. (1999). "Interaction of YB-1 with human immunodeficiency virus type 1 Tat and TAR RNA modulates viral promoter activity". J. Gen. Virol. 80 ( Pt 10): 2629–38. PMID 10573156.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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