ELF5

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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n/a

RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

E74-like factor 5 (ets domain transcription factor), is a gene found in both mice and humans.[1] In humans it is also called ESE2.

Function

The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.[1]

References

  1. 1.0 1.1 "Entrez Gene: ELF5 E74-like factor 5 (ets domain transcription factor)".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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