Hepatocyte nuclear factor 4 gamma: Difference between revisions

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{{Infobox_gene}} __NOTOC__
{{PBB_Controls
'''Hepatocyte nuclear factor 4 gamma''' ('''HNF4G''') also known as '''NR2A2''' (nuclear receptor subfamily 2, group A, member 2) is a [[nuclear receptor]] that in humans is encoded by the ''HNF4G'' ''gene''.<ref name="entrez">{{cite web | title = Entrez Gene: HNF4G hepatocyte nuclear factor 4, gamma| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3174| accessdate = }}</ref><ref name="pmid8622695">{{cite journal | vauthors = Drewes T, Senkel S, Holewa B, Ryffel GU | title = Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes | journal = Molecular and Cellular Biology | volume = 16 | issue = 3 | pages = 925–31 | date = March 1996 | pmid = 8622695 | pmc = 231074 | doi = 10.1128/mcb.16.3.925 }}</ref><ref name="pmid12220494">{{cite journal | vauthors = Wisely GB, Miller AB, Davis RG, Thornquest AD, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP | title = Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids | journal = Structure | volume = 10 | issue = 9 | pages = 1225–34 | date = September 2002 | pmid = 12220494 | doi = 10.1016/S0969-2126(02)00829-8 }}</ref>
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}}<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_HNF4G_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1lv2.
| PDB = {{PDB2|1lv2}}
| Name = Hepatocyte nuclear factor 4, gamma
| HGNCid = 5026
| Symbol = HNF4G
| AltSymbols =; NR2A2
| OMIM = 605966
| ECnumber = 
| Homologene = 37886
| MGIid = 1353604
| GeneAtlas_image1 = PBB_GE_HNF4G_207456_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003707 |text = steroid hormone receptor activity}} {{GNF_GO|id=GO:0005496 |text = steroid binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0016439 |text = tRNA-pseudouridine synthase activity}} {{GNF_GO|id=GO:0016563 |text = transcription activator activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3174
    | Hs_Ensembl = ENSG00000164749
    | Hs_RefseqProtein = NP_004124
    | Hs_RefseqmRNA = NM_004133
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 76482826
    | Hs_GenLoc_end = 76639117
    | Hs_Uniprot = Q14541
    | Mm_EntrezGene = 30942
    | Mm_Ensembl = ENSMUSG00000017688
    | Mm_RefseqmRNA = NM_013920
    | Mm_RefseqProtein = NP_038948
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 3493753
    | Mm_GenLoc_end = 3643025
    | Mm_Uniprot = Q059V1
  }}
}}
'''Hepatocyte nuclear factor 4 gamma''' ('''HNF4G''') also known as '''NR2A2''' (nuclear receptor subfamily 2, group A, member 2) is a [[nuclear receptor]] encoded by the {{gene|HNF4G}} gene.<ref name="entrez">{{cite web | title = Entrez Gene: HNF4G hepatocyte nuclear factor 4, gamma| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3174| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== See also ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==See also==
*[[Hepatocyte nuclear factor 4]]
*[[Hepatocyte nuclear factor 4]]
*[[Hepatocyte nuclear factors]]
*[[Hepatocyte nuclear factors]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Plengvidhya N, Antonellis A, Wogan LT, Poleev A, Borgschulze M, Warram JH, Ryffel GU, Krolewski AS, Doria A | title = Hepatocyte nuclear factor-4gamma: cDNA sequence, gene organization, and mutation screening in early-onset autosomal-dominant type 2 diabetes | journal = Diabetes | volume = 48 | issue = 10 | pages = 2099–102 | date = October 1999 | pmid = 10512380 | doi = 10.2337/diabetes.48.10.2099 }}
| citations =
* {{cite journal | vauthors = Ozeki T, Takahashi Y, Nakayama K, Funayama M, Nagashima K, Kodama T, Kamataki T | title = Hepatocyte nuclear factor-4 alpha/gamma and hepatocyte nuclear factor-1 alpha as causal factors of interindividual difference in the expression of human dihydrodiol dehydrogenase 4 mRNA in human livers | journal = Pharmacogenetics | volume = 13 | issue = 1 | pages = 49–53 | date = January 2003 | pmid = 12544512 | doi = 10.1097/00008571-200301000-00007 }}
*{{cite journal | author=Drewes T, Senkel S, Holewa B, Ryffel GU |title=Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes. |journal=Mol. Cell. Biol. |volume=16 |issue= 3 |pages= 925-31 |year= 1996 |pmid= 8622695 |doi=  }}
*{{cite journal  | author=Plengvidhya N, Antonellis A, Wogan LT, ''et al.'' |title=Hepatocyte nuclear factor-4gamma: cDNA sequence, gene organization, and mutation screening in early-onset autosomal-dominant type 2 diabetes. |journal=Diabetes |volume=48 |issue= 10 |pages= 2099-102 |year= 1999 |pmid= 10512380 |doi=  }}
*{{cite journal  | author=Wisely GB, Miller AB, Davis RG, ''et al.'' |title=Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids. |journal=Structure |volume=10 |issue= 9 |pages= 1225-34 |year= 2003 |pmid= 12220494 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Ozeki T, Takahashi Y, Nakayama K, ''et al.'' |title=Hepatocyte nuclear factor-4 alpha/gamma and hepatocyte nuclear factor-1 alpha as causal factors of interindividual difference in the expression of human dihydrodiol dehydrogenase 4 mRNA in human livers. |journal=Pharmacogenetics |volume=13 |issue= 1 |pages= 49-53 |year= 2003 |pmid= 12544512 |doi=  }}
*{{cite journal  | author=Nusbaum C, Mikkelsen TS, Zody MC, ''et al.'' |title=DNA sequence and analysis of human chromosome 8. |journal=Nature |volume=439 |issue= 7074 |pages= 331-5 |year= 2006 |pmid= 16421571 |doi= 10.1038/nature04406 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
== External links ==
{{Transcription factors}}
* {{FactorBook|HNF4G}}
 
{{PDB Gallery|geneid=3174}}
{{Transcription factors|g2}}
 
[[Category:Intracellular receptors]]
[[Category:Intracellular receptors]]
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
{{gene-8-stub}}

Latest revision as of 08:41, 10 January 2019

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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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Wikidata
View/Edit Human

Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is encoded by the HNF4G gene.[1][2][3]

See also

References

  1. ↑ "Entrez Gene: HNF4G hepatocyte nuclear factor 4, gamma".
  2. ↑ Drewes T, Senkel S, Holewa B, Ryffel GU (March 1996). "Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes". Molecular and Cellular Biology. 16 (3): 925–31. doi:10.1128/mcb.16.3.925. PMC 231074. PMID 8622695.
  3. ↑ Wisely GB, Miller AB, Davis RG, Thornquest AD, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP (September 2002). "Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids". Structure. 10 (9): 1225–34. doi:10.1016/S0969-2126(02)00829-8. PMID 12220494.

Further reading

  • Plengvidhya N, Antonellis A, Wogan LT, Poleev A, Borgschulze M, Warram JH, Ryffel GU, Krolewski AS, Doria A (October 1999). "Hepatocyte nuclear factor-4gamma: cDNA sequence, gene organization, and mutation screening in early-onset autosomal-dominant type 2 diabetes". Diabetes. 48 (10): 2099–102. doi:10.2337/diabetes.48.10.2099. PMID 10512380.
  • Ozeki T, Takahashi Y, Nakayama K, Funayama M, Nagashima K, Kodama T, Kamataki T (January 2003). "Hepatocyte nuclear factor-4 alpha/gamma and hepatocyte nuclear factor-1 alpha as causal factors of interindividual difference in the expression of human dihydrodiol dehydrogenase 4 mRNA in human livers". Pharmacogenetics. 13 (1): 49–53. doi:10.1097/00008571-200301000-00007. PMID 12544512.

External links

Retrieved from "https://www.wikidoc.org/index.php?title=Hepatocyte_nuclear_factor_4_gamma&oldid=1523625"