HOXB5: Difference between revisions

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Orthologs
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Latest revision as of 02:00, 27 October 2017

Homeobox protein Hox-B5 is a protein that in humans is encoded by the HOXB5 gene.^[1]^[2]^[3]

Function

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.^[3]

References

↑ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
↑ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.
↑ ^3.0 ^3.1 "Entrez Gene: HOXB5 homeobox B5".

Galang CK, Hauser CA (May 1992). "Cooperative DNA binding of the highly conserved human Hox 2.1 homeodomain gene product". The New Biologist. 4 (5): 558–68. PMID 1355360.
Peverali FA, D'Esposito M, Acampora D, Bunone G, Negri M, Faiella A, Stornaiuolo A, Pannese M, Migliaccio E, Simeone A (Oct 1990). "Expression of HOX homeogenes in human neuroblastoma cell culture lines". Differentiation; Research in Biological Diversity. 45 (1): 61–9. doi:10.1111/j.1432-0436.1990.tb00458.x. PMID 1981366.
Giampaolo A, Acampora D, Zappavigna V, Pannese M, D'Esposito M, Carè A, Faiella A, Stornaiuolo A, Russo G, Simeone A (Jun 1989). "Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system". Differentiation; Research in Biological Diversity. 40 (3): 191–7. doi:10.1111/j.1432-0436.1989.tb00598.x. PMID 2570724.
Acampora D, D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncinelli E (Dec 1989). "The human HOX gene family". Nucleic Acids Research. 17 (24): 10385–402. doi:10.1093/nar/17.24.10385. PMC 335308. PMID 2574852.
Boncinelli E, Acampora D, Pannese M, D'Esposito M, Somma R, Gaudino G, Stornaiuolo A, Cafiero M, Faiella A, Simeone A (1990). "Organization of human class I homeobox genes". Genome / National Research Council Canada = Génome / Conseil National De Recherches Canada. 31 (2): 745–56. doi:10.1139/g89-133. PMID 2576652.
Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH (Dec 1986). "Cognate homeo-box loci mapped on homologous human and mouse chromosomes". Proceedings of the National Academy of Sciences of the United States of America. 83 (23): 9104–8. doi:10.1073/pnas.83.23.9104. PMC 387083. PMID 2878432.
Hart CP, Awgulewitsch A, Fainsod A, McGinnis W, Ruddle FH (Nov 1985). "Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus". Cell. 43 (1): 9–18. doi:10.1016/0092-8674(85)90007-8. PMID 3000607.
Xu WM, Gorman PA, Rider SH, Hedge PJ, Moore G, Prichard C, Sheer D, Solomon E (Nov 1988). "Construction of a genetic map of human chromosome 17 by use of chromosome-mediated gene transfer". Proceedings of the National Academy of Sciences of the United States of America. 85 (22): 8563–7. doi:10.1073/pnas.85.22.8563. PMC 282499. PMID 3186746.
Simeone A, Mavilio F, Bottero L, Giampaolo A, Russo G, Faiella A, Boncinelli E, Peschle C (1986). "A human homoeo box gene specifically expressed in spinal cord during embryonic development". Nature. 320 (6064): 763–5. doi:10.1038/320763a0. PMID 3453105.
Hauser CA, Joyner AL, Klein RD, Learned TK, Martin GR, Tjian R (Nov 1985). "Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos". Cell. 43 (1): 19–28. doi:10.1016/0092-8674(85)90008-X. PMID 4075393.
Levine M, Rubin GM, Tjian R (Oct 1984). "Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila". Cell. 38 (3): 667–73. doi:10.1016/0092-8674(84)90261-7. PMID 6091895.
Galang CK, Hauser CA (Aug 1993). "Cooperative DNA binding of the human HoxB5 (Hox-2.1) protein is under redox regulation in vitro". Molecular and Cellular Biology. 13 (8): 4609–17. doi:10.1128/mcb.13.8.4609. PMC 360087. PMID 8101633.
Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B (1996). "Fine mapping of human HOX gene clusters". Cytogenetics and Cell Genetics. 73 (1–2): 114–5. doi:10.1159/000134320. PMID 8646877.
Kuliev A, Kukharenko V, Morozov G, Freidine M, Rechitsky S, Verlinsky O, Ivakhnenko V, Gindilis V, Strom C, Verlinsky Y (Feb 1996). "Expression of homebox-containing genes in human preimplantation development and in embryos with chromosomal aneuploidies". Journal of Assisted Reproduction and Genetics. 13 (2): 177–81. doi:10.1007/BF02072541. PMID 8688592.
Sakach M, Safaei R (Aug 1996). "Localization of the HoxB5 protein in the developing CNS of late gestational mouse embryos". International Journal of Developmental Neuroscience. 14 (5): 567–73. doi:10.1016/0736-5748(96)00052-4. PMID 8930688.
Archavachotikul K, Ciccone TJ, Chinoy MR, Nielsen HC, Volpe MV (Mar 2002). "Thyroid hormone affects embryonic mouse lung branching morphogenesis and cellular differentiation". American Journal of Physiology. Lung Cellular and Molecular Physiology. 282 (3): L359–69. doi:10.1152/ajplung.00400.2000. PMID 11839528.
Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, Tomita M, McGinnis W, Matsuo N (Feb 2002). "Complete mutation analysis panel of the 39 human HOX genes". Teratology. 65 (2): 50–62. doi:10.1002/tera.10009. PMID 11857506.

External links

HOXB5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[pmid1973146-1] McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-2] Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.

[entrez-3] 3.0 ^3.1 "Entrez Gene: HOXB5 homeobox B5".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Homeobox protein Hox-B5''' is a [[protein]] that in humans is encoded by the ''HOXB5'' [[gene]].<ref name="pmid1973146">{{cite journal | vauthors = McAlpine PJ, Shows TB | title = Nomenclature for human homeobox genes | journal = Genomics | volume = 7 | issue = 3 | pages = 460 | date = Jul 1990 | pmid = 1973146 | pmc =  | doi = 10.1016/0888-7543(90)90186-X }}</ref><ref name="pmid1358459">{{cite journal | vauthors = Scott MP | title = Vertebrate homeobox gene nomenclature | journal = Cell | volume = 71 | issue = 4 | pages = 551–3 | date = Nov 1992 | pmid = 1358459 | pmc =  | doi = 10.1016/0092-8674(92)90588-4 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HOXB5 homeobox B5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3215| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Function ==
-{{GNF_Protein_box
- | image = PBB_Protein_HOXB5_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1hom.
- | PDB = {{PDB2|1hom}}, {{PDB2|1san}}
- | Name = Homeobox B5
- | HGNCid = 5116
- | Symbol = HOXB5
- | AltSymbols =; HOX2; HHO.C10; HOX2A; HU-1; Hox2.1
- | OMIM = 142960
- | ECnumber =
- | Homologene = 37585
- | MGIid = 96186
- | GeneAtlas_image1 = PBB_GE_HOXB5_205601_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_HOXB5_205600_x_at_tn.png
- | Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0009653 |text = anatomical structure morphogenesis}} {{GNF_GO|id=GO:0045446 |text = endothelial cell differentiation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 3215
-    | Hs_Ensembl = ENSG00000120075
-    | Hs_RefseqProtein = NP_002138
-    | Hs_RefseqmRNA = NM_002147
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 17
-    | Hs_GenLoc_start = 44023619
-    | Hs_GenLoc_end = 44026322
-    | Hs_Uniprot = P09067
-    | Mm_EntrezGene = 15413
-    | Mm_Ensembl = ENSMUSG00000038700
-    | Mm_RefseqmRNA = NM_008268
-    | Mm_RefseqProtein = NP_032294
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 11
-    | Mm_GenLoc_start = 96119602
-    | Mm_GenLoc_end = 96122210
-    | Mm_Uniprot = Q9CZV0
-  }}
-}}
-'''Homeobox B5''', also known as '''HOXB5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HOXB5 homeobox B5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3215| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.<ref name="entrez" />
-{{PBB_Summary
-| section_title =
-| summary_text = This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.<ref name="entrez">{{cite web | title = Entrez Gene: HOXB5 homeobox B5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3215| accessdate = }}</ref>
-}}
-==See also==
+== See also ==
 * [[Homeobox]]
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Galang CK, Hauser CA | title = Cooperative DNA binding of the highly conserved human Hox 2.1 homeodomain gene product | journal = The New Biologist | volume = 4 | issue = 5 | pages = 558–68 | date = May 1992 | pmid = 1355360 | doi =  }}
-| citations =
+* {{cite journal | vauthors = Peverali FA, D'Esposito M, Acampora D, Bunone G, Negri M, Faiella A, Stornaiuolo A, Pannese M, Migliaccio E, Simeone A | title = Expression of HOX homeogenes in human neuroblastoma cell culture lines | journal = Differentiation; Research in Biological Diversity | volume = 45 | issue = 1 | pages = 61–9 | date = Oct 1990 | pmid = 1981366 | doi = 10.1111/j.1432-0436.1990.tb00458.x }}
-*{{cite journal  | author=Galang CK, Hauser CA |title=Cooperative DNA binding of the highly conserved human Hox 2.1 homeodomain gene product. |journal=New Biol. |volume=4 |issue= 5 |pages= 558-68 |year= 1992 |pmid= 1355360 |doi=  }}
+* {{cite journal | vauthors = Giampaolo A, Acampora D, Zappavigna V, Pannese M, D'Esposito M, Carè A, Faiella A, Stornaiuolo A, Russo G, Simeone A | title = Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system | journal = Differentiation; Research in Biological Diversity | volume = 40 | issue = 3 | pages = 191–7 | date = Jun 1989 | pmid = 2570724 | doi = 10.1111/j.1432-0436.1989.tb00598.x }}
-*{{cite journal  | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551-3 |year= 1992 |pmid= 1358459 |doi=  }}
+* {{cite journal | vauthors = Acampora D, D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncinelli E | title = The human HOX gene family | journal = Nucleic Acids Research | volume = 17 | issue = 24 | pages = 10385–402 | date = Dec 1989 | pmid = 2574852 | pmc = 335308 | doi = 10.1093/nar/17.24.10385 }}
-*{{cite journal  | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=  }}
+* {{cite journal | vauthors = Boncinelli E, Acampora D, Pannese M, D'Esposito M, Somma R, Gaudino G, Stornaiuolo A, Cafiero M, Faiella A, Simeone A | title = Organization of human class I homeobox genes | journal = Genome / National Research Council Canada = Génome / Conseil National De Recherches Canada | volume = 31 | issue = 2 | pages = 745–56 | year = 1990 | pmid = 2576652 | doi = 10.1139/g89-133 }}
-*{{cite journal  | author=Peverali FA, D'Esposito M, Acampora D, ''et al.'' |title=Expression of HOX homeogenes in human neuroblastoma cell culture lines. |journal=Differentiation |volume=45 |issue= 1 |pages= 61-9 |year= 1991 |pmid= 1981366 |doi=  }}
+* {{cite journal | vauthors = Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH | title = Cognate homeo-box loci mapped on homologous human and mouse chromosomes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 83 | issue = 23 | pages = 9104–8 | date = Dec 1986 | pmid = 2878432 | pmc = 387083 | doi = 10.1073/pnas.83.23.9104 }}
-*{{cite journal  | author=Giampaolo A, Acampora D, Zappavigna V, ''et al.'' |title=Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system. |journal=Differentiation |volume=40 |issue= 3 |pages= 191-7 |year= 1989 |pmid= 2570724 |doi=  }}
+* {{cite journal | vauthors = Hart CP, Awgulewitsch A, Fainsod A, McGinnis W, Ruddle FH | title = Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus | journal = Cell | volume = 43 | issue = 1 | pages = 9–18 | date = Nov 1985 | pmid = 3000607 | doi = 10.1016/0092-8674(85)90007-8 }}
-*{{cite journal  | author=Acampora D, D'Esposito M, Faiella A, ''et al.'' |title=The human HOX gene family. |journal=Nucleic Acids Res. |volume=17 |issue= 24 |pages= 10385-402 |year= 1990 |pmid= 2574852 |doi=  }}
+* {{cite journal | vauthors = Xu WM, Gorman PA, Rider SH, Hedge PJ, Moore G, Prichard C, Sheer D, Solomon E | title = Construction of a genetic map of human chromosome 17 by use of chromosome-mediated gene transfer | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 85 | issue = 22 | pages = 8563–7 | date = Nov 1988 | pmid = 3186746 | pmc = 282499 | doi = 10.1073/pnas.85.22.8563 }}
-*{{cite journal  | author=Boncinelli E, Acampora D, Pannese M, ''et al.'' |title=Organization of human class I homeobox genes. |journal=Genome |volume=31 |issue= 2 |pages= 745-56 |year= 1990 |pmid= 2576652 |doi=  }}
+* {{cite journal | vauthors = Simeone A, Mavilio F, Bottero L, Giampaolo A, Russo G, Faiella A, Boncinelli E, Peschle C | title = A human homoeo box gene specifically expressed in spinal cord during embryonic development | journal = Nature | volume = 320 | issue = 6064 | pages = 763–5 | year = 1986 | pmid = 3453105 | doi = 10.1038/320763a0 }}
-*{{cite journal  | author=Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH |title=Cognate homeo-box loci mapped on homologous human and mouse chromosomes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 23 |pages= 9104-8 |year= 1987 |pmid= 2878432 |doi=  }}
+* {{cite journal | vauthors = Hauser CA, Joyner AL, Klein RD, Learned TK, Martin GR, Tjian R | title = Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos | journal = Cell | volume = 43 | issue = 1 | pages = 19–28 | date = Nov 1985 | pmid = 4075393 | doi = 10.1016/0092-8674(85)90008-X }}
-*{{cite journal  | author=Hart CP, Awgulewitsch A, Fainsod A, ''et al.'' |title=Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus. |journal=Cell |volume=43 |issue= 1 |pages= 9-18 |year= 1986 |pmid= 3000607 |doi=  }}
+* {{cite journal | vauthors = Levine M, Rubin GM, Tjian R | title = Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila | journal = Cell | volume = 38 | issue = 3 | pages = 667–73 | date = Oct 1984 | pmid = 6091895 | doi = 10.1016/0092-8674(84)90261-7 }}
-*{{cite journal  | author=Xu WM, Gorman PA, Rider SH, ''et al.'' |title=Construction of a genetic map of human chromosome 17 by use of chromosome-mediated gene transfer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 22 |pages= 8563-7 |year= 1988 |pmid= 3186746 |doi=  }}
+* {{cite journal | vauthors = Galang CK, Hauser CA | title = Cooperative DNA binding of the human HoxB5 (Hox-2.1) protein is under redox regulation in vitro | journal = Molecular and Cellular Biology | volume = 13 | issue = 8 | pages = 4609–17 | date = Aug 1993 | pmid = 8101633 | pmc = 360087 | doi =  10.1128/mcb.13.8.4609}}
-*{{cite journal  | author=Simeone A, Mavilio F, Bottero L, ''et al.'' |title=A human homoeo box gene specifically expressed in spinal cord during embryonic development. |journal=Nature |volume=320 |issue= 6064 |pages= 763-5 |year= 1986 |pmid= 3453105 |doi= 10.1038/320763a0 }}
+* {{cite journal | vauthors = Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B | title = Fine mapping of human HOX gene clusters | journal = Cytogenetics and Cell Genetics | volume = 73 | issue = 1-2 | pages = 114–5 | year = 1996 | pmid = 8646877 | doi = 10.1159/000134320 }}
-*{{cite journal  | author=Hauser CA, Joyner AL, Klein RD, ''et al.'' |title=Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos. |journal=Cell |volume=43 |issue= 1 |pages= 19-28 |year= 1986 |pmid= 4075393 |doi=  }}
+* {{cite journal | vauthors = Kuliev A, Kukharenko V, Morozov G, Freidine M, Rechitsky S, Verlinsky O, Ivakhnenko V, Gindilis V, Strom C, Verlinsky Y | title = Expression of homebox-containing genes in human preimplantation development and in embryos with chromosomal aneuploidies | journal = Journal of Assisted Reproduction and Genetics | volume = 13 | issue = 2 | pages = 177–81 | date = Feb 1996 | pmid = 8688592 | doi = 10.1007/BF02072541 }}
-*{{cite journal  | author=Levine M, Rubin GM, Tjian R |title=Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila. |journal=Cell |volume=38 |issue= 3 |pages= 667-73 |year= 1984 |pmid= 6091895 |doi=  }}
+* {{cite journal | vauthors = Sakach M, Safaei R | title = Localization of the HoxB5 protein in the developing CNS of late gestational mouse embryos | journal = International Journal of Developmental Neuroscience | volume = 14 | issue = 5 | pages = 567–73 | date = Aug 1996 | pmid = 8930688 | doi = 10.1016/0736-5748(96)00052-4 }}
-*{{cite journal  | author=Galang CK, Hauser CA |title=Cooperative DNA binding of the human HoxB5 (Hox-2.1) protein is under redox regulation in vitro. |journal=Mol. Cell. Biol. |volume=13 |issue= 8 |pages= 4609-17 |year= 1993 |pmid= 8101633 |doi=  }}
+* {{cite journal | vauthors = Archavachotikul K, Ciccone TJ, Chinoy MR, Nielsen HC, Volpe MV | title = Thyroid hormone affects embryonic mouse lung branching morphogenesis and cellular differentiation | journal = American Journal of Physiology. Lung Cellular and Molecular Physiology | volume = 282 | issue = 3 | pages = L359-69 | date = Mar 2002 | pmid = 11839528 | doi = 10.1152/ajplung.00400.2000 }}
-*{{cite journal  | author=Apiou F, Flagiello D, Cillo C, ''et al.'' |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114-5 |year= 1996 |pmid= 8646877 |doi=  }}
+* {{cite journal | vauthors = Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, Tomita M, McGinnis W, Matsuo N | title = Complete mutation analysis panel of the 39 human HOX genes | journal = Teratology | volume = 65 | issue = 2 | pages = 50–62 | date = Feb 2002 | pmid = 11857506 | doi = 10.1002/tera.10009 }}
-*{{cite journal  | author=Kuliev A, Kukharenko V, Morozov G, ''et al.'' |title=Expression of homebox-containing genes in human preimplantation development and in embryos with chromosomal aneuploidies. |journal=J. Assist. Reprod. Genet. |volume=13 |issue= 2 |pages= 177-81 |year= 1996 |pmid= 8688592 |doi=  }}
-*{{cite journal  | author=Sakach M, Safaei R |title=Localization of the HoxB5 protein in the developing CNS of late gestational mouse embryos. |journal=Int. J. Dev. Neurosci. |volume=14 |issue= 5 |pages= 567-73 |year= 1997 |pmid= 8930688 |doi=  }}
-*{{cite journal  | author=Archavachotikul K, Ciccone TJ, Chinoy MR, ''et al.'' |title=Thyroid hormone affects embryonic mouse lung branching morphogenesis and cellular differentiation. |journal=Am. J. Physiol. Lung Cell Mol. Physiol. |volume=282 |issue= 3 |pages= L359-69 |year= 2002 |pmid= 11839528 |doi= 10.1152/ajplung.00400.2000 }}
-*{{cite journal  | author=Kosaki K, Kosaki R, Suzuki T, ''et al.'' |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50-62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-}}
 {{refend}}
@@ Line 92: / Line 37: @@
 {{NLM content}}
-{{protein-stub}}
+{{gene-17-stub}}
-{{Transcription factors}}
+{{PDB Gallery|geneid=3215}}
+{{Transcription factors|g3}}
 [[Category:Transcription factors]]
-{{WikiDoc Sources}}

HOXB5: Difference between revisions

Latest revision as of 02:00, 27 October 2017

Contents

Function

See also

References

Further reading

External links

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