HBP1: Difference between revisions

Jump to navigation Jump to search
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''HMG-box transcription factor 1''', also known as '''HBP1''', is a human [[protein]].<ref name="entrez">{{cite web | title = Entrez Gene: HBP1 HMG-box transcription factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26959| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_HBP1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1v06.
| PDB = {{PDB2|1v06}}
| Name = HMG-box transcription factor 1
| HGNCid = 23200
| Symbol = HBP1
| AltSymbols =; FLJ16340
| OMIM = 
| ECnumber = 
| Homologene = 8171
| MGIid = 894659
| GeneAtlas_image1 = PBB_GE_HBP1_209102_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007050 |text = cell cycle arrest}} {{GNF_GO|id=GO:0016055 |text = Wnt receptor signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 26959
    | Hs_Ensembl = ENSG00000105856
    | Hs_RefseqProtein = NP_036389
    | Hs_RefseqmRNA = NM_012257
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 106596696
    | Hs_GenLoc_end = 106630209
    | Hs_Uniprot = O60381
    | Mm_EntrezGene = 73389
    | Mm_Ensembl = ENSMUSG00000002996
    | Mm_RefseqmRNA = NM_153198
    | Mm_RefseqProtein = NP_694878
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 32511707
    | Mm_GenLoc_end = 32535470
    | Mm_Uniprot = Q3UQS1
  }}
}}
'''HMG-box transcription factor 1''', also known as '''HBP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HBP1 HMG-box transcription factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26959| accessdate = }}</ref>
 
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
{{PBB_Summary
Line 53: Line 6:
| summary_text =  
| summary_text =  
}}
}}
==Interactions==
HBP1 has been shown to [[Protein–protein interaction|interact]] with [[SIN3A]]<ref name=pmid15235594>{{cite journal |last=Swanson |first=Kurt A |authorlink= |author2=Knoepfler Paul S |author3=Huang Kai |author4=Kang Richard S |author5=Cowley Shaun M |author6=Laherty Carol D |author7=Eisenman Robert N |author8=Radhakrishnan Ishwar  |date=Aug 2004 |title=HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations |journal=Nat. Struct. Mol. Biol. |volume=11 |issue=8 |pages=738–46 |publisher= |location = United States| issn = 1545-9993| pmid = 15235594 |doi = 10.1038/nsmb798 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[Retinoblastoma protein]].<ref name=pmid9178770>{{cite journal |last=Lavender |first=P |authorlink= |author2=Vandel L |author3=Bannister A J |author4=Kouzarides T  |date=Jun 1997 |title=The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A |journal=Oncogene |volume=14 |issue=22 |pages=2721–8 |publisher= |location = ENGLAND| issn = 0950-9232| pmid = 9178770 |doi = 10.1038/sj.onc.1201243 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Tevosian SG, Shih HH, Mendelson KG, ''et al.'' |title=HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family. |journal=Genes Dev. |volume=11 |issue= 3 |pages= 383-96 |year= 1997 |pmid= 9030690 |doi=  }}
*{{cite journal   |vauthors=Tevosian SG, Shih HH, Mendelson KG, etal |title=HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family. |journal=Genes Dev. |volume=11 |issue= 3 |pages= 383–96 |year= 1997 |pmid= 9030690 |doi=10.1101/gad.11.3.383 }}
*{{cite journal  | author=Lavender P, Vandel L, Bannister AJ, Kouzarides T |title=The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A. |journal=Oncogene |volume=14 |issue= 22 |pages= 2721-8 |year= 1997 |pmid= 9178770 |doi= 10.1038/sj.onc.1201243 }}
*{{cite journal  |vauthors=Lavender P, Vandel L, Bannister AJ, Kouzarides T |title=The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A. |journal=Oncogene |volume=14 |issue= 22 |pages= 2721–8 |year= 1997 |pmid= 9178770 |doi= 10.1038/sj.onc.1201243 }}
*{{cite journal | author=Zhuma T, Tyrrell R, Sekkali B, ''et al.'' |title=Human HMG box transcription factor HBP1: a role in hCD2 LCR function. |journal=EMBO J. |volume=18 |issue= 22 |pages= 6396-406 |year= 2000 |pmid= 10562551 |doi= 10.1093/emboj/18.22.6396 }}
*{{cite journal   |vauthors=Zhuma T, Tyrrell R, Sekkali B, etal |title=Human HMG box transcription factor HBP1: a role in hCD2 LCR function |journal=EMBO J. |volume=18 |issue= 22 |pages= 6396–406 |year= 2000 |pmid= 10562551 |doi= 10.1093/emboj/18.22.6396 | pmc=1171702 }}
*{{cite journal | author=Lemercier C, Duncliffe K, Boibessot I, ''et al.'' |title=Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression. |journal=Mol. Cell. Biol. |volume=20 |issue= 18 |pages= 6627-37 |year= 2000 |pmid= 10958660 |doi=  }}
*{{cite journal   |vauthors=Lemercier C, Duncliffe K, Boibessot I, etal |title=Involvement of Retinoblastoma Protein and HBP1 in Histone H10 Gene Expression |journal=Mol. Cell. Biol. |volume=20 |issue= 18 |pages= 6627–37 |year= 2000 |pmid= 10958660 |doi=10.1128/MCB.20.18.6627-6637.2000  | pmc=86159 }}
*{{cite journal | author=Shih HH, Xiu M, Berasi SP, ''et al.'' |title=HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissue. |journal=Mol. Cell. Biol. |volume=21 |issue= 17 |pages= 5723-32 |year= 2001 |pmid= 11486012 |doi=  }}
*{{cite journal   |vauthors=Shih HH, Xiu M, Berasi SP, etal |title=HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue |journal=Mol. Cell. Biol. |volume=21 |issue= 17 |pages= 5723–32 |year= 2001 |pmid= 11486012 |doi=10.1128/MCB.21.17.5723-5732.2001  | pmc=87292 }}
*{{cite journal | author=Sampson EM, Haque ZK, Ku MC, ''et al.'' |title=Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. |journal=EMBO J. |volume=20 |issue= 16 |pages= 4500-11 |year= 2001 |pmid= 11500377 |doi= 10.1093/emboj/20.16.4500 }}
*{{cite journal   |vauthors=Sampson EM, Haque ZK, Ku MC, etal |title=Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1 |journal=EMBO J. |volume=20 |issue= 16 |pages= 4500–11 |year= 2001 |pmid= 11500377 |doi= 10.1093/emboj/20.16.4500 | pmc=125566 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal   |vauthors=Hillier LW, Fulton RS, Fulton LA, etal |title=The DNA sequence of human chromosome 7 |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=de Chiara C, Kelly G, Frenkiel TA, Pastore A |title=Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1. |journal=J. Biomol. NMR |volume=28 |issue= 4 |pages= 411-2 |year= 2004 |pmid= 14872137 |doi= 10.1023/B:JNMR.0000015367.92295.0f }}
*{{cite journal  |vauthors=de Chiara C, Kelly G, Frenkiel TA, Pastore A |title=Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1 |journal=J. Biomol. NMR |volume=28 |issue= 4 |pages= 411–2 |year= 2004 |pmid= 14872137 |doi= 10.1023/B:JNMR.0000015367.92295.0f }}
*{{cite journal  | author=Berasi SP, Xiu M, Yee AS, Paulson KE |title=HBP1 repression of the p47phox gene: cell cycle regulation via the NADPH oxidase. |journal=Mol. Cell. Biol. |volume=24 |issue= 7 |pages= 3011-24 |year= 2004 |pmid= 15024088 |doi=  }}
*{{cite journal  |vauthors=Berasi SP, Xiu M, Yee AS, Paulson KE |title=HBP1 Repression of the p47phox Gene: Cell Cycle Regulation via the NADPH Oxidase |journal=Mol. Cell. Biol. |volume=24 |issue= 7 |pages= 3011–24 |year= 2004 |pmid= 15024088 |doi=10.1128/MCB.24.7.3011-3024.2004  | pmc=371097 }}
*{{cite journal | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal   |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional Proteomics Mapping of a Human Signaling Pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148 }}
*{{cite journal | author=Swanson KA, Knoepfler PS, Huang K, ''et al.'' |title=HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. |journal=Nat. Struct. Mol. Biol. |volume=11 |issue= 8 |pages= 738-46 |year= 2004 |pmid= 15235594 |doi= 10.1038/nsmb798 }}
*{{cite journal   |vauthors=Swanson KA, Knoepfler PS, Huang K, etal |title=HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations |journal=Nat. Struct. Mol. Biol. |volume=11 |issue= 8 |pages= 738–46 |year= 2004 |pmid= 15235594 |doi= 10.1038/nsmb798 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal  | author=Yao CJ, Works K, Romagnoli PA, Austin GE |title=Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells. |journal=Leukemia |volume=19 |issue= 11 |pages= 1958-68 |year= 2005 |pmid= 16179914 |doi= 10.1038/sj.leu.2403918 }}
*{{cite journal  |vauthors=Yao CJ, Works K, Romagnoli PA, Austin GE |title=Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells |journal=Leukemia |volume=19 |issue= 11 |pages= 1958–68 |year= 2005 |pmid= 16179914 |doi= 10.1038/sj.leu.2403918 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein–protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Sekkali B, Szabat E, Ktistaki E, ''et al.'' |title=Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation. |journal=J. Immunol. |volume=175 |issue= 8 |pages= 5203-12 |year= 2005 |pmid= 16210625 |doi=  }}
*{{cite journal   |vauthors=Sekkali B, Szabat E, Ktistaki E, etal |title=Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation |journal=J. Immunol. |volume=175 |issue= 8 |pages= 5203–12 |year= 2005 |pmid= 16210625 |doi=  10.4049/jimmunol.175.8.5203}}
*{{cite journal | author=Kim J, Zhang X, Rieger-Christ KM, ''et al.'' |title=Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1. |journal=J. Biol. Chem. |volume=281 |issue= 16 |pages= 10865-75 |year= 2006 |pmid= 16495219 |doi= 10.1074/jbc.M513378200 }}
*{{cite journal   |vauthors=Kim J, Zhang X, Rieger-Christ KM, etal |title=Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1 |journal=J. Biol. Chem. |volume=281 |issue= 16 |pages= 10865–75 |year= 2006 |pmid= 16495219 |doi= 10.1074/jbc.M513378200 }}
*{{cite journal | author=Lim J, Hao T, Shaw C, ''et al.'' |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801-14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
*{{cite journal   |vauthors=Lim J, Hao T, Shaw C, etal |title=A protein–protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
*{{cite journal | author=Zhang X, Kim J, Ruthazer R, ''et al.'' |title=The HBP1 transcriptional repressor participates in RAS-induced premature senescence. |journal=Mol. Cell. Biol. |volume=26 |issue= 22 |pages= 8252-66 |year= 2007 |pmid= 16966377 |doi= 10.1128/MCB.00604-06 }}
*{{cite journal   |vauthors=Zhang X, Kim J, Ruthazer R, etal |title=The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence |journal=Mol. Cell. Biol. |volume=26 |issue= 22 |pages= 8252–66 |year= 2007 |pmid= 16966377 |doi= 10.1128/MCB.00604-06 | pmc=1636767 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=26959}}


== External links ==
== External links ==
* {{MeshName|HBP1+protein,+human}}
* {{MeshName|HBP1+protein,+human}}


{{protein-stub}}
{{Transcription factors|g0}}
{{Transcription factors}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{gene-7-stub}}

Revision as of 13:29, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

HMG-box transcription factor 1, also known as HBP1, is a human protein.[1]

Interactions

HBP1 has been shown to interact with SIN3A[2] and Retinoblastoma protein.[3]

References

  1. "Entrez Gene: HBP1 HMG-box transcription factor 1".
  2. Swanson, Kurt A; Knoepfler Paul S; Huang Kai; Kang Richard S; Cowley Shaun M; Laherty Carol D; Eisenman Robert N; Radhakrishnan Ishwar (Aug 2004). "HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations". Nat. Struct. Mol. Biol. United States. 11 (8): 738–46. doi:10.1038/nsmb798. ISSN 1545-9993. PMID 15235594.
  3. Lavender, P; Vandel L; Bannister A J; Kouzarides T (Jun 1997). "The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A". Oncogene. ENGLAND. 14 (22): 2721–8. doi:10.1038/sj.onc.1201243. ISSN 0950-9232. PMID 9178770.

Further reading

External links