CEBPG

CCAAT/enhancer binding protein (C/EBP), gamma
Identifiers
Symbols	CEBPG ; GPE1BP; IG/EBP-1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1368
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

CCAAT/enhancer binding protein (C/EBP), gamma, also known as CEBPG, is a human gene.

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements.

See also

• Ccaat-enhancer-binding proteins

Further reading

• Nishizawa M, Nagata S (1992). "cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein". FEBS Lett. 299 (1): 36–8. PMID 1371974.
• Thomassin H, Hamel D, Bernier D; et al. (1992). "Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma". Nucleic Acids Res. 20 (12): 3091–8. PMID 1377818.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nishizawa M, Wakabayashi-Ito N, Nagata S (1991). "Molecular cloning of cDNA and a chromosomal gene encoding GPE1-BP, a nuclear protein which binds to granulocyte colony-stimulating factor promoter element 1". FEBS Lett. 282 (1): 95–7. PMID 1709121.CS1 maint: Multiple names: authors list (link)
• Williams SC, Cantwell CA, Johnson PF (1991). "A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro". Genes Dev. 5 (9): 1553–67. PMID 1884998.CS1 maint: Multiple names: authors list (link)
• Cooper C, Henderson A, Artandi S; et al. (1996). "Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators". Nucleic Acids Res. 23 (21): 4371–7. PMID 7501458.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Davydov IV, Bohmann D, Krammer PH, Li-Weber M (1995). "Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter". Gene. 161 (2): 271–5. PMID 7665092.CS1 maint: Multiple names: authors list (link)
• Lundgren M, Larsson C, Femino A; et al. (1994). "Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site". J. Immunol. 153 (7): 2983–95. PMID 8089482.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martin ML, Lieberman PM, Curran T (1996). "Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF". Mol. Cell. Biol. 16 (5): 2110–8. PMID 8628277.CS1 maint: Multiple names: authors list (link)
• Gao H, Parkin S, Johnson PF, Schwartz RC (2002). "C/EBP gamma has a stimulatory role on the IL-6 and IL-8 promoters". J. Biol. Chem. 277 (41): 38827–37. doi:10.1074/jbc.M206224200. PMID 12177065.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hattori T, Ohoka N, Inoue Y; et al. (2003). "C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer". Oncogene. 22 (9): 1273–80. doi:10.1038/sj.onc.1206204. PMID 12618752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Newman JR, Keating AE (2003). "Comprehensive identification of human bZIP interactions with coiled-coil arrays". Science. 300 (5628): 2097–101. doi:10.1126/science.1084648. PMID 12805554.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mullins DN, Crawford EL, Khuder SA; et al. (2006). "CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma". BMC Cancer. 5: 141. doi:10.1186/1471-2407-5-141. PMID 16255782.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• CEBPG+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.