Aprobarbital

Aprobarbital

Clinical data
Synonyms	aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid
AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	N05CA05 (WHO)
Identifiers
IUPAC name 5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
CAS Number	77-02-1 Y
PubChem CID	6464
DrugBank	DB01352 Y
ChemSpider	6221 Y
UNII	Q0YKG9L6RF
KEGG	D00698 Y
ChEBI	CHEBI:2791 Y
ChEMBL	ChEMBL7863 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C10H14N2O3
Molar mass	210.23 g/mol
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(C(C)C)C\C=C
InChI InChI=1S/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15) Y Key:UORJNBVJVRLXMQ-UHFFFAOYSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Aprobarbital (as known in the United States, or aprobarbitone (as known elsewhere), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.