CCRL1
| Chemokine (C-C motif) receptor-like 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | CCRL1 ; CCBP2; CCR10; CC-CKR-11; CCR11; CCX-CKR; CKR-11; PPR1; VSHK1 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 49474 | ||||||||||
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| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Chemokine (C-C motif) receptor-like 1, also known as CCRL1, is a human gene.[1]
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described.[1]
References
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Bacon KB, Schall TJ, Dairaghi DJ (1998). "RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA". J. Immunol. 160 (4): 1894–900. PMID 9469451.
- Gosling J, Dairaghi DJ, Wang Y; et al. (2000). "Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK". J. Immunol. 164 (6): 2851–6. PMID 10706668.
- Schweickart VL, Epp A, Raport CJ, Gray PW (2000). "CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines". J. Biol. Chem. 275 (13): 9550–6. PMID 10734104.
- Khoja H, Wang G, Ng CT; et al. (2000). "Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart". Gene. 246 (1–2): 229–38. PMID 10767544.
- Schweickart VL, Epp A, Raport CJ, Gray PW. "CCR11 is a functional receptor for the monocyte chemoaattractant protein family of chemokines". 276 (1): 856. PMID 11134065.
- Townson JR, Nibbs RJ (2002). "Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR". Eur. J. Immunol. 32 (5): 1230–41. doi:10.1002/1521-4141(200205)32:5<1230::AID-IMMU1230>3.0.CO;2-L. PMID 11981810.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Comerford I, Milasta S, Morrow V; et al. (2006). "The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro". Eur. J. Immunol. 36 (7): 1904–16. doi:10.1002/eji.200535716. PMID 16791897.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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