List of chemotherapeutic agents: Difference between revisions

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__NOTOC__
__NOTOC__
{{SI}}
{{Seealso|Chemotherapy regimens}}
{{Seealso|Chemotherapy regimens}}
{{CMG}}; {{AE}} {{AV}}; {{AP}}
{{CMG}}; {{AE}} {{AV}}; {{Steven}}


==Overview==
==Overview==
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== Chemotherapeutic Agents by Category ==
== Chemotherapeutic Agents by Category ==


{{button|Cytotoxic Chemotherapy}}
=== Alkylating agents ===


===== Alkylating agents =====
====== Nitrogen mustards ======
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Estramustine |Estramustine  (Emcyt)]]
* [[Ifosfamide|Ifosfamide (Iflex)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
 
====== Ethylenimines ======
* [[Thiotepa|Thiotepa (Tepadina)]]
 
====== Methylhydrazines ======
* [[Procarbazine|Procarbazine (Matulane)]]
 
====== Alkylsulfonates ======
* [[Busulfan|Busulfan (Myleran)]]
 
====== Nitrosoureas ======
* [[Bendamustine|Bendamustine (Treanda)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Streptozocin|Streptozocin (Zanosar)]]


*[[Bendamustine|Bendamustine (Treanda)]]
====== Triazenes ======
*[[Busulfan|Busulfan (Myleran)]]
* [[Altretamine|Altretamine (Hexalen)]]
*[[Carmustine|Carmustine (BiCNU)]]
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]]
*[[Estramustine|Estramustine (Emcyt)]]
* [[Temozolomide|Temozolomide (Temodar)]]
*[[Ifosfamide|Ifosfamide (Iflex)]]
*[[Lomustine|Lomustine (CeeNU)]]
*[[Mechlorethamine|Mechlorethamine (Mustargen)]]
*[[Melphalan|Melphalan (Alkeran)]]
*[[Procarbazine|Procarbazine (Matulane)]]


===== Anthracyclines =====
====== Platinum coordination complexes ======
*[[Idarubicin hydrochloride|Idarubicin (Idamycin)]]
* [[Carboplatin|Carboplatin (Paraplatin)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]


----


===== Antimetabolites =====
=== Antimetabolites ===
*[[Capecitabine|Capecitabine (Xeloda)]]
*[[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
*[[Gemcitabine|Gemcitabine (Gemzar)]]
*[[Hydroxyurea|Hydroxyurea (Hydrea)]]
*[[Mercaptopurine|Mercaptopurine (Purinethol)]]
*[[Methotrexate|Methotrexate (Mexate,Folex)]]


===== Antimitotic agent=====
====== Folic acid analogs ======
*[[Etoposide|Etoposide (Vespid)]]
* [[Methotrexate|Methotrexate (Mexate, Folex)]]
*[[Ixabepilone|Ixabepilone (Ixempra)]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
*[[Vinblastine|Vinblastine (Velban,Velsar)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
*[[Vincristine|Vincristine (Oncovin,Vincasar)]]
*[[Vinorelbine|Vinorelbine (Navelbine)]]


====== Pyrimidine analogs ======
* [[Azacytidine|Azacytidine (Vidaza)]]
* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]


===== DNA synthesis inhibitors =====
====== Purine analogs ======
*[[Streptozocin|Streptozocin (Zanosar)]]
* [[Cladribine|Cladribine (Leustatin)]]
* [[Clofarabine|Clofarabine (Clolar)]]
* [[Fludarabine|Fludarabine (Fludara)]]
* [[Mercaptopurine|Mercaptopurine (Purinethol)]]
* [[Nelarabine|Nelarabine (Arranon)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Thioguanine|Thioguanine (Tabloid)]]


===== Microtubule inhibitors =====
====== Ribonucleotide reductase inhibitors ======
*[[Ixabepilone|Ixabepilone (Ixempra)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]


===== Nitrogen mustards =====
----
*[[Mechlorethamine|Mechlorethamine (Mustargen)]]


===== Nitrosureas =====
=== Natural products ===
*[[Lomustine|Lomustine (CeeNU)]]


===== Platinum agents =====
====== Vinca alkaloids ======
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposome|Vincristine liposome (Marqibo)]]
* [[Vinflunine|Vinflunine (Javlor)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]


===== Proteasome inhibitors =====
====== Taxanes ======
*[[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]


===== Taxanes =====
====== Epipodophyllotoxins ======
* [[Etoposide|Etoposide (Vespid)]]
* [[Teniposide|Teniposide (Vumon)]]


===== Topoisomerase inhibitors =====
====== Camptothecins ======
*[[Irinotecan hydrochloride|Irinotecan (Camptosar)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Topotecan|Topotecan (Hycamtin)]]


===== Vinca alkaloids =====
====== Antineoplastic antibiotics ======
*[[Vinblastine|Vinblastine (Velban,Velsar)]]
* [[Bleomycin|Bleomycin (Blenoxane)]]
*[[Vincristine|Vincristine (Oncovin,Vincasar)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Daunorubicin |Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Idarubicin|Idarubicin (Idamycin)]]
* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Valrubicin|Valrubicin (Valstar)]]


====== Antineoplastic enzymes ======
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]


----
----


{{Button|Endocrine therapy}}
=== Hormones and Antagonists ===
 
====== Adrenocortical suppressants ======
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
 
* [[Mitotane|Mitotane (Lysodren)]]
* [[Trilostane|Trilostane (Modrenal)]]
 
====== Glucocorticoids ======
* [[Dexamethasone|Dexamethasone (Decadron)]]
* [[Prednisone|Prednisone (Deltasone)]]
 
====== Progestins ======
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
 
====== Estrogens ======
* [[Esterified estrogens|Esterified estrogens (Menest)]]
 
====== Anti-estrogens ======
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Toremifene|Toremifene (Fareston)]]
 
====== Aromatase inhibitors ======
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Letrozole|Letrozole (Femara)]]
 
====== Androgens ======
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Testolactone|Testolactone (Teslac)]]


===== Antiandrogens =====
====== Anti-androgens ======
* [[Abarelix|Abarelix (Plenaxis)]]
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Dutasteride|Dutasteride (Avodart)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Finasteride|Finasteride (Proscar)]]
* [[Flutamide|Flutamide (Eulexin)]]  
* [[Flutamide|Flutamide (Eulexin)]]
* [[Ketoconazole|Ketoconazole (Nizoral)]]
* [[Leuprolide|Leuprolide (Lupron)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
* [[Triptorelin|Triptorelin (Trelstar)]]
===== Steroid synthesis inhibitors =====
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Letrozole|Letrozole (Femara)]]
* [[Mitotane|Mitotane (Lysodren)]]


===== Androgen receptor inhibitors =====
====== LHRH agonists ======
*[[Nilutamide|Nilutamide (Nilandron)]]


===== 5α-reductase inhibitors =====
* [[Triptorelin|Triptorelin (Trelstar)]]


===== GnRH agonists =====
===== GnRH agonists =====
* [[Buserelin|Buserelin (Superfact)]]
* [[Buserelin|Buserelin (Superfact)]]  
* [[Goserelin Acetate|Goserelin Acetate (Zoladex)]]
* [[Goserelin|Goserelin (Zoladex)]]
* [[Leuprolide|Leuprolide (Lupron)]]
* [[Leuprolide|Leuprolide (Lupron)]]


===== GnRH antagonists =====
===== GnRH antagonists =====
*[[Degarelix|Degarelix (Firmagon)]]
* [[Degarelix|Degarelix (Firmagon)]]
 
----
 
=== Biologics ===


===== Aromatase inhibitors =====
===== Monoclonal antibodies =====
*[[Anastrozole|Anastrozole (Arimidex)]]
*[[Exemestane|Exemestane (Aromasin))]]
*[[Letrozole|Letrozole (Femara)]]
===== Selective estrogen receptor modulators =====


----
====== Anti-CD3 antibodies ======
* [[Catumaxomab|Catumaxomab (Removab)]]


{{Button|Biologics}}
====== Anti-CD3 & anti-CD19 antibodies ======
* [[Blinatumomab|Blinatumomab (Blincyto)]]


===== Antibody medications =====
====== Anti-CD20 antibodies ======
*[[Cetuximab|Cetuximab (Erbitux)]]
* [[Rituximab|Rituximab (Rituxan)]]
*[[Denosumab|Denosumab (Xgeva)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin))]]
*[[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
*[[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
*[[Nivolumab |Nivolumab (Opdivo)]]
* [[Tositumomab|Tositumomab (Bexxar)]]
*[[Obinutuzumab|Obinutuzumab (Gazyva)]]
*[[Ofatumumab|Ofatumumab (Arzerra)]]
*[[Pembrolizumab|Pembrolizumab (KEYTRUDA)]]


====== Anti-CD30 antibodies ======
* [[Brentuximab|Brentuximab (Adcetris)]]


===== Antibody-drug conjugates =====
====== Anti-CD33 antibodies ======
*[[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Gemtuzumab|Gemtuzumab (Mylotarg)]]
*[[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
*[[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]


===== Anti-HER2 medications =====
====== Anti-CD52 antibodies ======
*[[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Alemtuzumab|Alemtuzumab (Campath)]]
*[[Trastuzumab|Trastuzumab (Herceptin)]]


===== Enzymes =====
====== Anti-CTLA–4 antibodies ======
*[[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
*[[Glucarpidase|Glucarpidase (Voraxaze)]]


===== IL-6 inhibitors =====
====== Anti-EGFR (ErbB1) antibodies ======
*[[Siltuximab|Siltuximab (Sylvant)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
 
====== Anti-PD–1 antibodies ======
* [[Nivolumab |Nivolumab (Opdivo)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]


===== IL-2 inhibitors =====
====== Anti-HER2/neu (ErbB2) antibodies ======
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab (Kadcyla)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]


===== Immunotherapy =====
====== Anti-VEGF antibodies ======
*[[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Bevacizumab|Bevacizumab (Avastin)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]


===== Immunomodulatory drugs (IMiDs) =====
===== IL-6 inhibitors =====
* [[Siltuximab|Siltuximab (Sylvant)]]
* [[Tocilizumab|Tocilizumab (Actemra)]]


* [[Lenalidomide|Lenalidomide (Revlimid)]]
===== Immunotherapy =====
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]


----
----


{{Button|Hematopoietic Growth Factors}}
=== Hematopoietic Growth Factors ===


===== Erythrocyte growth factors =====
===== Erythrocyte growth factors =====
*[[Erythropoietin|Erythropoietin (Procrit)]]
* [[Erythropoietin|Erythropoietin (Procrit)]]


===== Granulocyte growth factors =====
===== Granulocyte growth factors =====
*[[Filgrastim|Filgrastim (Granix)]]
* [[Filgrastim|Filgrastim (Neupogen)]]
*[[Sargramostim|Sargramostin (Leukine)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
*[[Tbo-filgrastim|Tbo-filgrastim (Granix)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Sargramostim|Sargramostin (Leukine, Leukomax)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]


===== Megakaryocyte growth factors =====
===== Megakaryocyte growth factors =====
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Romiplostim|Romiplostim (Nplate)]]
* [[Oprelvekin|Oprelvekin (Neumega)]]


----
----


{{Button|Supportive Medications}}
=== Supportive Medications ===


===== Chemotherapy protective agents =====
===== Chemotherapy protective agents =====
*[[Amifostine|Amifostine (Ethyol)]]
* [[Amifostine|Amifostine (Ethyol)]]
*[[Cyanocobalamin|Cyanocobalamin]]
* [[Cyanocobalamin|Cyanocobalamin (Cobal)]]
*[[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
*[[Folinic acid|Folinic acid (Leucovorin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
*[[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
*[[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
*[[Mesna|Mesna (Mesnex)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Rasburicase|Rasburicase (Elitek)]]


===== Antiemetic agents =====
===== Antiemetic agents =====
*[[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]]
* [[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]]


===== RANK ligand inhibitors =====
===== RANK ligand inhibitors =====
* [[Denosumab|Denosumab (Xgeva)]]
* [[Denosumab|Denosumab (Xgeva)]]
===== Calcium regulators =====
* [[Gallium nitrate|Gallium nitrate (Ganite)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]]


----
----


{{Button|Miscellaneous}}
=== Miscellaneous ===
 
===== Mitotic inhibitors =====
* [[Amsacrine|Amsacrine (Amsidine)]]
* [[Cabazitaxel|Cabazitaxel (Jevtana)]]
* [[Eribulin|Eribulin (Halaven)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]


===== HDAC inhibitors =====
===== HDAC inhibitors =====
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* [[Romidepsin|Romidepsin (Istodax)]]
* [[Romidepsin|Romidepsin (Istodax)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
===== Hedgehog pathway inhibitors =====
* [[Vismodegib|Vismodegib (Erivedge)]]
===== Immunomodulatory drugs (IMiDs) =====
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]]
* [[Thalidomide|Thalidomide (Thalomid)]]


===== Kinase inhibitors =====
===== Kinase inhibitors =====
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Axitinib|Axitinib (Inlyta)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Everolimus|Everolimus (Afinitor)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lenvatinib|Lenvatinib (Lenvima)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Ruxolitinib|Ruxolitinib (Jakafi)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
===== Photosensitizing agents =====
* [[Aminolevulinic acid |Aminolevulinic acid (Levulan)]]
* [[Porfimer|Porfimer (Photofrin)]]
===== Proteasome inhibitors =====
* [[Bortezomib|Bortezomib (Velcade)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]


===== Radioactive agents =====
===== Radioactive agents =====
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]


* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
===== Somatostatin analogs =====
* [[Octreotide|Octreotide (Octreotide)]]


===== VEGF receptor-2 antagonists =====
===== Differentiating agents =====
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Bexarotene|Bexarotene (Targretin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]


----
===== Orphan drugs =====
* [[Olaparib|Olaparib (Lynparza)]]
* [[Omacetaxine|Omacetaxine (Synribo)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Trabectedin|Trabectedin (Yondelis)]]


== Chemotherapeutic Agents in Alphabetical Order ==
== Chemotherapeutic Agents in Alphabetical Order ==
* [[Abiraterone|Abiraterone (Zytiga)]]
{{Columns-list|3|
* [[Ado-trastuzumab|Ado-trastuzumab (Kadcyla)]]
* [[Abarelix|Abarelix (Plenaxis)]]
* [[Abiraterone|Abiraterone acetate (Zytiga)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Alemtuzumab|Alemtuzumab (Campath)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Aminolevulinic acid|Aminolevulinic acid (Levulan)]]
* [[Amsacrine|Amsacrine (Amsidine)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
Line 241: Line 381:
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Blinatumomab|Blinatumomab (Blincyto)]]
* [[Blinatumomab|Blinatumomab (Blincyto)]]
* [[Bortezomib|Bortezomib (Velcade)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
Line 251: Line 392:
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Catumaxomab|Catumaxomab (Removab)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Cladribine|Cladribine (Leustatin)]]
* [[Clofarabine|Clofarabine (Clolar)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Cytarabine liposome|Cytarabine liposome (DepoCyt)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Daunorubicin|Daunorubicin (Daunoxome)]]
* [[Daunorubicin|Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Degarelix|Degarelix (Firmagon)]]
* [[Degarelix|Degarelix (Firmagon)]]
Line 267: Line 417:
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Doxorubicin liposome|Doxorubicin liposome (Doxil, Lipodox)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Epirubicin|Epirubicin (Ellence)]]
Line 272: Line 423:
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]]
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]]
* [[Esterified estrogens|Esterified estrogens (Menest)]]
* [[Estramustine|Estramustine (Emcyt)]]
* [[Estramustine|Estramustine (Emcyt)]]
* [[Etoposide|Etoposide (Vespid)]]
* [[Etoposide|Etoposide (Vespid)]]
Line 282: Line 434:
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Folinic acid|Folinic acid (Leucovorin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Gallium nitrate|Gallium Nitrate (Ganite)]]
* [[Gallium nitrate|Gallium Nitrate (Ganite)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Goserelin|Goserelin (Zoladex)]]
* [[Goserelin acetate|Goserelin Acetate (Zoladex)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
Line 295: Line 449:
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Ifosfamide|Ifosfamide (Ifex)]]
* [[Ifosfamide|Ifosfamide (Ifex)]]
* [[interferon alfa-2b|interferon alfa-2b (Intron A)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Isotretinoin|Isotretinoin (Accutane)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
Line 309: Line 463:
* [[Lomustine|Lomustine (CeeNU)]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone (Provera)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Melphalan|Melphalan (Alkeran)]]
Line 331: Line 485:
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
* [[Pazopanib|Pazopanib (Votrient)]]
* [[Pazopanib|Pazopanib (Votrient)]]
* [[Pegaspargase|PEG-Asparaginase (Oncaspar)]]
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
Line 342: Line 498:
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Ponatinib|Ponatinib (Iclusig)]]
* [[Ponatinib|Ponatinib (Iclusig)]]
* [[Porfimer|Porfimer (Photofrin)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Procarbazine|Procarbazine (Matulane)]]
* [[Procarbazine|Procarbazine (Matulane)]]
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Rasburicase|Rasburicase (Elitek)]]
* [[Rasburicase|Rasburicase (Elitek)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
Line 366: Line 528:
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Teniposide|Teniposide (Vumon)]]
* [[Teniposide|Teniposide (Vumon)]]
* [[Testolactone|Testolactone (Teslac)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
Line 372: Line 535:
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Tositumomab|Tositumomab (Bexxar)]]
* [[Trabectedin|Trabectedin (Yondelis)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Triptorelin|Triptorelin (Trelstar)]]
* [[Trilostane|Trilostane (Modrenal)]]
* [[Triptorelin pamoate|Triptorelin pamoate (Trelstar)]]
* [[Valrubicin|Valrubicin (Valstar)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposomal|Vincristine liposomal (Marqibo)]]
* [[Vincristine liposome|Vincristine liposome (Marqibo)]]
* [[Vinflunine|Vinflunine (Javlor)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
* [[Vismodegib|Vismodegib (Erivedge)]]
* [[Vismodegib|Vismodegib (Erivedge)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Zoledronate|Zoledronate (Zometa)]]
* [[Zoledronic acid|Zoledronic Acid (Zometa)]]
}}


[[Category:Chemotherapeutic agents| ]]
[[Category:Chemotherapeutic agents| ]]

Latest revision as of 04:08, 22 March 2015

Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]

Overview

This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).

Chemotherapeutic Agents by Category

Alkylating agents

Nitrogen mustards
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes

Antimetabolites

Folic acid analogs
Pyrimidine analogs
Purine analogs
Ribonucleotide reductase inhibitors

Natural products

Vinca alkaloids
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
Antineoplastic enzymes

Hormones and Antagonists

Adrenocortical suppressants
Glucocorticoids
Progestins
Estrogens
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
LHRH agonists
GnRH agonists
GnRH antagonists

Biologics

Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-6 inhibitors
Immunotherapy

Hematopoietic Growth Factors

Erythrocyte growth factors
Granulocyte growth factors
Megakaryocyte growth factors

Supportive Medications

Chemotherapy protective agents
Antiemetic agents
RANK ligand inhibitors
Calcium regulators

Miscellaneous

Mitotic inhibitors
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Orphan drugs

Chemotherapeutic Agents in Alphabetical Order

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