List of chemotherapeutic agents: Difference between revisions

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__NOTOC__
__NOTOC__
{{SI}}
{{Seealso|Chemotherapy regimens}}
{{Seealso|Chemotherapy regimens}}
{{CMG}}; {{AE}} {{AV}}; {{AP}}
{{CMG}}; {{AE}} {{AV}}; {{Steven}}


==Overview==
==Overview==
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== Chemotherapeutic Agents by Category ==
== Chemotherapeutic Agents by Category ==


{{button|Cytotoxic Chemotherapy}}
=== Alkylating agents ===


===== Alkylating agents =====
====== Nitrogen mustards ======
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Estramustine |Estramustine  (Emcyt)]]
* [[Ifosfamide|Ifosfamide (Iflex)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]


*[[Bendamustine|Bendamustine (Treanda)]]  
====== Ethylenimines ======
* [[Thiotepa|Thiotepa (Tepadina)]]


*[[Busulfan|Busulfan (Myleran)]]
====== Methylhydrazines ======
* [[Procarbazine|Procarbazine (Matulane)]]


*[[Carmustine|Carmustine (BiCNU)]]
====== Alkylsulfonates ======
* [[Busulfan|Busulfan (Myleran)]]


*[[Estramustine|Estramustine (Emcyt)]]
====== Nitrosoureas ======
*[[Procarbazine|Procarbazine (Matulane)]]
* [[Bendamustine|Bendamustine (Treanda)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Streptozocin|Streptozocin (Zanosar)]]


===== Anthracyclines =====
====== Triazenes ======
*[[Idarubicin hydrochloride|Idarubicin (Idamycin)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]]
* [[Temozolomide|Temozolomide (Temodar)]]


===== Antimetabolites =====
====== Platinum coordination complexes ======
*[[Capecitabine|Capecitabine (Xeloda)]]
* [[Carboplatin|Carboplatin (Paraplatin)]]
*[[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
 
----


===== Antimitotic agent=====
=== Antimetabolites ===
*[[Dexrazoxane]]


===== DNA synthesis inhibitors =====
====== Folic acid analogs ======
*[[Streptozocin|Streptozocin (Zanosar)]]
* [[Methotrexate|Methotrexate (Mexate, Folex)]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]


===== Microtubule inhibitors =====
====== Pyrimidine analogs ======
*[[Ixabepilone|Ixabepilone (Ixempra)]]
* [[Azacytidine|Azacytidine (Vidaza)]]
* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]


===== Nitrogen mustards =====
====== Purine analogs ======
* [[Cladribine|Cladribine (Leustatin)]]
* [[Clofarabine|Clofarabine (Clolar)]]
* [[Fludarabine|Fludarabine (Fludara)]]
* [[Mercaptopurine|Mercaptopurine (Purinethol)]]
* [[Nelarabine|Nelarabine (Arranon)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Thioguanine|Thioguanine (Tabloid)]]


===== Nitrosureas =====
====== Ribonucleotide reductase inhibitors ======
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]


===== Platinum agents =====
----


===== Proteasome inhibitors =====
=== Natural products ===
*[[Carfilzomib|Carfilzomib (Kyprolis)]]


===== Taxanes =====
====== Vinca alkaloids ======
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposome|Vincristine liposome (Marqibo)]]
* [[Vinflunine|Vinflunine (Javlor)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]


===== Topoisomerase inhibitors =====
====== Taxanes ======
*[[Irinotecan hydrochloride|Irinotecan (Camptosar)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]


===== Vinca alkaloids =====
====== Epipodophyllotoxins ======
* [[Etoposide|Etoposide (Vespid)]]
* [[Teniposide|Teniposide (Vumon)]]


====== Camptothecins ======
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Topotecan|Topotecan (Hycamtin)]]
====== Antineoplastic antibiotics ======
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Daunorubicin |Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Idarubicin|Idarubicin (Idamycin)]]
* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Valrubicin|Valrubicin (Valstar)]]
====== Antineoplastic enzymes ======
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]


----
----


{{Button|Endocrine therapy}}
=== Hormones and Antagonists ===
 
====== Adrenocortical suppressants ======
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
 
* [[Mitotane|Mitotane (Lysodren)]]
* [[Trilostane|Trilostane (Modrenal)]]


===== Antiandrogens =====
====== Glucocorticoids ======
* [[Dexamethasone|Dexamethasone (Decadron)]]
* [[Prednisone|Prednisone (Deltasone)]]
 
====== Progestins ======
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
 
====== Estrogens ======
* [[Esterified estrogens|Esterified estrogens (Menest)]]
 
====== Anti-estrogens ======
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Toremifene|Toremifene (Fareston)]]
 
====== Aromatase inhibitors ======
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Letrozole|Letrozole (Femara)]]
 
====== Androgens ======
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Testolactone|Testolactone (Teslac)]]
 
====== Anti-androgens ======
* [[Abarelix|Abarelix (Plenaxis)]]
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Dutasteride|Dutasteride (Avodart)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Finasteride|Finasteride (Proscar)]]
* [[Flutamide|Flutamide (Eulexin)]]  
* [[Flutamide|Flutamide (Eulexin)]]
* [[Ketoconazole|Ketoconazole (Nizoral)]]
* [[Leuprolide|Leuprolide (Lupron)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
====== LHRH agonists ======
* [[Triptorelin|Triptorelin (Trelstar)]]
* [[Triptorelin|Triptorelin (Trelstar)]]


===== Steroid synthesis inhibitors =====
===== GnRH agonists =====
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Buserelin|Buserelin (Superfact)]]  
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Goserelin|Goserelin (Zoladex)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Leuprolide|Leuprolide (Lupron)]]
* [[Exemestane|Exemestane (Aromasin)]]
 
* [[Letrozole|Letrozole (Femara)]]
===== GnRH antagonists =====
* [[Degarelix|Degarelix (Firmagon)]]
 
----
 
=== Biologics ===
 
===== Monoclonal antibodies =====


===== Androgen receptor inhibitors =====
====== Anti-CD3 antibodies ======
*[[Nilutamide|Nilutamide (Nilandron)]]
* [[Catumaxomab|Catumaxomab (Removab)]]


===== -reductase inhibitors =====
====== Anti-CD3 & anti-CD19 antibodies ======
* [[Blinatumomab|Blinatumomab (Blincyto)]]


===== GnRH agonists =====
====== Anti-CD20 antibodies ======
* [[Buserelin|Buserelin (Superfact)]]
* [[Rituximab|Rituximab (Rituxan)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin))]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
* [[Tositumomab|Tositumomab (Bexxar)]]


===== GnRH antagonists =====
====== Anti-CD30 antibodies ======
*[[Degarelix|Degarelix (Firmagon)]]
* [[Brentuximab|Brentuximab (Adcetris)]]


===== Aromatase inhibitors =====
====== Anti-CD33 antibodies ======
*[[Anastrozole|Anastrozole (Arimidex)]]
* [[Gemtuzumab|Gemtuzumab (Mylotarg)]]
===== Selective estrogen receptor modulators =====


----
====== Anti-CD52 antibodies ======
* [[Alemtuzumab|Alemtuzumab (Campath)]]


{{Button|Biologics}}
====== Anti-CTLA–4 antibodies ======
* [[Ipilimumab|Ipilimumab (Yervoy)]]


===== Antibody medications =====
====== Anti-EGFR (ErbB1) antibodies ======
*[[Ibritumomab tiuxetan]]
* [[Cetuximab|Cetuximab (Erbitux)]]
*[[Nivolumab |Nivolumab (Opdivo)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
*[[Pembrolizumab|Pembrolizumab (KEYTRUDA)]]


===== Antibody-drug conjugates =====
====== Anti-PD–1 antibodies ======
*[[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Nivolumab |Nivolumab (Opdivo)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]


===== Anti-HER2 medications =====
====== Anti-HER2/neu (ErbB2) antibodies ======
*[[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab (Kadcyla)]]
*[[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]


===== Enzymes =====
====== Anti-VEGF antibodies ======
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Bevacizumab|Bevacizumab (Avastin)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]


===== IL-6 inhibitors =====
===== IL-6 inhibitors =====
*[[Siltuximab|Siltuximab (Sylvant)]]
* [[Siltuximab|Siltuximab (Sylvant)]]
* [[Tocilizumab|Tocilizumab (Actemra)]]


===== IL-2 inhibitors =====
===== Immunotherapy =====
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
 
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
===== Immunotherapy =====
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
 
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
===== Immunomodulatory drugs (IMiDs) =====
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]


----
----


{{Button|Hematopoietic Growth Factors}}
=== Hematopoietic Growth Factors ===


===== Erythrocyte growth factors =====
===== Erythrocyte growth factors =====
* [[Erythropoietin|Erythropoietin (Procrit)]]


===== Granulocyte growth factors =====
===== Granulocyte growth factors =====
*[[Filgrastim|Filgrastim (Granix)]]
* [[Filgrastim|Filgrastim (Neupogen)]]
*[[Sargramostim|Sargramostin (Leukine)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
*[[Tbo-filgrastim|Tbo-filgrastim (Granix)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Sargramostim|Sargramostin (Leukine, Leukomax)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]


===== Megakaryocyte growth factors =====
===== Megakaryocyte growth factors =====
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Romiplostim|Romiplostim (Nplate)]]
* [[Oprelvekin|Oprelvekin (Neumega)]]


----
----


{{Button|Supportive Medications}}
=== Supportive Medications ===


===== Chemotherapy protective agents =====
===== Chemotherapy protective agents =====
*[[Amifostine|Amifostine (Ethyol)]]
* [[Amifostine|Amifostine (Ethyol)]]
*[[Cyanocobalamin|Cyanocobalamin]]
* [[Cyanocobalamin|Cyanocobalamin (Cobal)]]
*[[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
*[[Folinic acid|Folinic acid (Leucovorin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
*[[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
*[[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
*[[Mesna|Mesna (Mesnex)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Rasburicase|Rasburicase (Elitek)]]


===== Antiemetic agents =====
===== Antiemetic agents =====
*[[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]]
* [[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]]


===== RANK ligand inhibitors =====
===== RANK ligand inhibitors =====
* [[Denosumab|Denosumab (Xgeva)]]
* [[Denosumab|Denosumab (Xgeva)]]
===== Calcium regulators =====
* [[Gallium nitrate|Gallium nitrate (Ganite)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]]


----
----


{{Button|Miscellaneous}}
=== Miscellaneous ===
 
===== Mitotic inhibitors =====
* [[Amsacrine|Amsacrine (Amsidine)]]
* [[Cabazitaxel|Cabazitaxel (Jevtana)]]
* [[Eribulin|Eribulin (Halaven)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]


===== HDAC inhibitors =====
===== HDAC inhibitors =====
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* [[Romidepsin|Romidepsin (Istodax)]]
* [[Romidepsin|Romidepsin (Istodax)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
===== Hedgehog pathway inhibitors =====
* [[Vismodegib|Vismodegib (Erivedge)]]
===== Immunomodulatory drugs (IMiDs) =====
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]]
* [[Thalidomide|Thalidomide (Thalomid)]]


===== Kinase inhibitors =====
===== Kinase inhibitors =====
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Axitinib|Axitinib (Inlyta)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
 
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Everolimus|Everolimus (Afinitor)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lenvatinib|Lenvatinib (Lenvima)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Ruxolitinib|Ruxolitinib (Jakafi)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
===== Photosensitizing agents =====
* [[Aminolevulinic acid |Aminolevulinic acid (Levulan)]]
* [[Porfimer|Porfimer (Photofrin)]]
===== Proteasome inhibitors =====
* [[Bortezomib|Bortezomib (Velcade)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]


===== Radioactive agents =====
===== Radioactive agents =====
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]


* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
===== Somatostatin analogs =====
* [[Octreotide|Octreotide (Octreotide)]]


===== VEGF receptor-2 antagonists =====
===== Differentiating agents =====
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Bexarotene|Bexarotene (Targretin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]


----
===== Orphan drugs =====
* [[Olaparib|Olaparib (Lynparza)]]
* [[Omacetaxine|Omacetaxine (Synribo)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Trabectedin|Trabectedin (Yondelis)]]


== Chemotherapeutic Agents in Alphabetical Order ==
== Chemotherapeutic Agents in Alphabetical Order ==
* [[Abiraterone|Abiraterone (Zytiga)]]
{{Columns-list|3|
* [[Ado-trastuzumab|Ado-trastuzumab (Kadcyla)]]
* [[Abarelix|Abarelix (Plenaxis)]]
* [[Abiraterone|Abiraterone acetate (Zytiga)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Alemtuzumab|Alemtuzumab (Campath)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Aminolevulinic acid|Aminolevulinic acid (Levulan)]]
* [[Amsacrine|Amsacrine (Amsidine)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
Line 207: Line 381:
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Blinatumomab|Blinatumomab (Blincyto)]]
* [[Blinatumomab|Blinatumomab (Blincyto)]]
* [[Bortezomib|Bortezomib (Velcade)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
Line 217: Line 392:
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Catumaxomab|Catumaxomab (Removab)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Cladribine|Cladribine (Leustatin)]]
* [[Clofarabine|Clofarabine (Clolar)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Cytarabine liposome|Cytarabine liposome (DepoCyt)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Daunorubicin|Daunorubicin (Daunoxome)]]
* [[Daunorubicin|Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Degarelix|Degarelix (Firmagon)]]
* [[Degarelix|Degarelix (Firmagon)]]
Line 233: Line 417:
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Doxorubicin liposome|Doxorubicin liposome (Doxil, Lipodox)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Epirubicin|Epirubicin (Ellence)]]
Line 238: Line 423:
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]]
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]]
* [[Esterified estrogens|Esterified estrogens (Menest)]]
* [[Estramustine|Estramustine (Emcyt)]]
* [[Estramustine|Estramustine (Emcyt)]]
* [[Etoposide|Etoposide (Vespid)]]
* [[Etoposide|Etoposide (Vespid)]]
Line 248: Line 434:
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Folinic acid|Folinic acid (Leucovorin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Gallium nitrate|Gallium Nitrate (Ganite)]]
* [[Gallium nitrate|Gallium Nitrate (Ganite)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Goserelin|Goserelin (Zoladex)]]
* [[Goserelin acetate|Goserelin Acetate (Zoladex)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
Line 261: Line 449:
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Ifosfamide|Ifosfamide (Ifex)]]
* [[Ifosfamide|Ifosfamide (Ifex)]]
* [[interferon alfa-2b|interferon alfa-2b (Intron A)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Isotretinoin|Isotretinoin (Accutane)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
Line 275: Line 463:
* [[Lomustine|Lomustine (CeeNU)]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone (Provera)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Melphalan|Melphalan (Alkeran)]]
Line 297: Line 485:
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
* [[Pazopanib|Pazopanib (Votrient)]]
* [[Pazopanib|Pazopanib (Votrient)]]
* [[Pegaspargase|PEG-Asparaginase (Oncaspar)]]
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
Line 308: Line 498:
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Ponatinib|Ponatinib (Iclusig)]]
* [[Ponatinib|Ponatinib (Iclusig)]]
* [[Porfimer|Porfimer (Photofrin)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Procarbazine|Procarbazine (Matulane)]]
* [[Procarbazine|Procarbazine (Matulane)]]
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Rasburicase|Rasburicase (Elitek)]]
* [[Rasburicase|Rasburicase (Elitek)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
Line 332: Line 528:
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Teniposide|Teniposide (Vumon)]]
* [[Teniposide|Teniposide (Vumon)]]
* [[Testolactone|Testolactone (Teslac)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
Line 338: Line 535:
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Tositumomab|Tositumomab (Bexxar)]]
* [[Trabectedin|Trabectedin (Yondelis)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Triptorelin|Triptorelin (Trelstar)]]
* [[Trilostane|Trilostane (Modrenal)]]
* [[Triptorelin pamoate|Triptorelin pamoate (Trelstar)]]
* [[Valrubicin|Valrubicin (Valstar)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposomal|Vincristine liposomal (Marqibo)]]
* [[Vincristine liposome|Vincristine liposome (Marqibo)]]
* [[Vinflunine|Vinflunine (Javlor)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
* [[Vismodegib|Vismodegib (Erivedge)]]
* [[Vismodegib|Vismodegib (Erivedge)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Zoledronate|Zoledronate (Zometa)]]
* [[Zoledronic acid|Zoledronic Acid (Zometa)]]
}}


[[Category:Chemotherapeutic agents|Chemotherapeutic agents]]
[[Category:Chemotherapeutic agents| ]]

Latest revision as of 04:08, 22 March 2015

Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]

Overview

This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).

Chemotherapeutic Agents by Category

Alkylating agents

Nitrogen mustards
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes

Antimetabolites

Folic acid analogs
Pyrimidine analogs
Purine analogs
Ribonucleotide reductase inhibitors

Natural products

Vinca alkaloids
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
Antineoplastic enzymes

Hormones and Antagonists

Adrenocortical suppressants
Glucocorticoids
Progestins
Estrogens
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
LHRH agonists
GnRH agonists
GnRH antagonists

Biologics

Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-6 inhibitors
Immunotherapy

Hematopoietic Growth Factors

Erythrocyte growth factors
Granulocyte growth factors
Megakaryocyte growth factors

Supportive Medications

Chemotherapy protective agents
Antiemetic agents
RANK ligand inhibitors
Calcium regulators

Miscellaneous

Mitotic inhibitors
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Orphan drugs

Chemotherapeutic Agents in Alphabetical Order

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