List of chemotherapeutic agents: Difference between revisions

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__NOTOC__
__NOTOC__
{{SI}}
{{Seealso|Chemotherapy regimens}}
{{Seealso|Chemotherapy regimens}}
{{CMG}}; {{AE}} {{AV}}; {{Steven}}
{{CMG}}; {{AE}} {{AV}}; {{Steven}}
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* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Estramustine |Estramustine  (Emcyt)]]
* [[Ifosfamide|Ifosfamide (Iflex)]]
* [[Ifosfamide|Ifosfamide (Iflex)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Melphalan|Melphalan (Alkeran)]]
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* [[Methotrexate|Methotrexate (Mexate, Folex)]]
* [[Methotrexate|Methotrexate (Mexate, Folex)]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]


====== Pyrimidine analogs ======
====== Pyrimidine analogs ======
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* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]


====== Purine analogs ======
====== Purine analogs ======
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* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]


====== Epipodophyllotoxins ======
====== Epipodophyllotoxins ======
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* [[Teniposide|Teniposide (Vumon)]]
* [[Teniposide|Teniposide (Vumon)]]


====== Camptothecins/Topoisomerase inhibitors ======
====== Camptothecins ======
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Topotecan|Topotecan (Hycamtin)]]
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* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Daunorubicin|Daunorubicin (Daunoxome)]]
* [[Daunorubicin |Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Epirubicin|Epirubicin (Ellence)]]
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* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Valrubicin|Valrubicin (Valstar)]]
* [[Valrubicin|Valrubicin (Valstar)]]


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====== Adrenocortical suppressants ======
====== Adrenocortical suppressants ======
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Mitotane|Mitotane (Lysodren)]]
* [[Mitotane|Mitotane (Lysodren)]]
* [[Trilostane|Trilostane (Modrenal)]]


====== Adrenocortico-steroids ======
====== Glucocorticoids ======
* [[Dexamethasone|Dexamethasone (Decadron)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Prednisone|Prednisone (Deltasone)]]


====== Progestins ======
====== Progestins ======
* [[Medroxyprogesterone|Medroxyprogesterone (Provera)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Megestrol|Megestrol (Megace)]]
====== Estrogens ======
* [[Esterified estrogens|Esterified estrogens (Menest)]]


====== Anti-estrogens ======
====== Anti-estrogens ======
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Toremifene|Toremifene (Fareston)]]


====== Aromatase inhibitors ======
====== Aromatase inhibitors ======
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Letrozole|Letrozole (Femara)]]
* [[Letrozole|Letrozole (Femara)]]


====== Androgens ======
====== Androgens ======
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Testolactone|Testolactone (Teslac)]]


====== Anti-androgens ======
====== Anti-androgens ======
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====== Anti-CD20 antibodies ======
====== Anti-CD20 antibodies ======
* [[Rituximab|Rituximab (Rituxan)]]
* [[Rituximab|Rituximab (Rituxan)]]
* [[Ibritumomab|Ibritumomab (Zevalin)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin))]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
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====== Anti-HER2/neu (ErbB2) antibodies ======
====== Anti-HER2/neu (ErbB2) antibodies ======
* [[Ado-trastuzumab emtansine|Ado-trastuzumab (Kadcyla)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab (Kadcyla)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]


====== Anti-VEGF antibodies ======
====== Anti-VEGF antibodies ======
* [[Bevacizumab|Bevacizumab (Avastin)]]
* [[Bevacizumab|Bevacizumab (Avastin)]]
 
* [[Ramucirumab|Ramucirumab (Cyramza)]]
===== IL-2 inhibitors =====
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]


===== IL-6 inhibitors =====
===== IL-6 inhibitors =====
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===== Immunotherapy =====
===== Immunotherapy =====
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]


----
----
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===== Granulocyte growth factors =====
===== Granulocyte growth factors =====
* [[Filgrastim|Filgrastim (Granix)]]
* [[Filgrastim|Filgrastim (Neupogen)]]
* [[Sargramostim|Sargramostin (Leukine)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Sargramostim|Sargramostin (Leukine, Leukomax)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]


===== Megakaryocyte growth factors =====
===== Megakaryocyte growth factors =====
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Oprelvekin|Oprelvekin (Neumega)]]


----
----
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===== Chemotherapy protective agents =====
===== Chemotherapy protective agents =====
* [[Amifostine|Amifostine (Ethyol)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Cyanocobalamin|Cyanocobalamin]]
* [[Cyanocobalamin|Cyanocobalamin (Cobal)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Folinic acid|Folinic acid (Leucovorin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Rasburicase|Rasburicase (Elitek)]]


===== Antiemetic agents =====
===== Antiemetic agents =====
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===== RANK ligand inhibitors =====
===== RANK ligand inhibitors =====
* [[Denosumab|Denosumab (Xgeva)]]
* [[Denosumab|Denosumab (Xgeva)]]
===== Calcium regulators =====
* [[Gallium nitrate|Gallium nitrate (Ganite)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]]


----
----
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* [[Eribulin|Eribulin (Halaven)]]
* [[Eribulin|Eribulin (Halaven)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
===== Bisphosphonates =====
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]]


===== HDAC inhibitors =====
===== HDAC inhibitors =====
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* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]]
* [[Thalidomide|Thalidomide (Thalomid)]]


===== Kinase inhibitors =====
===== Kinase inhibitors =====
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* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Everolimus|Everolimus (Afinitor)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lenvatinib|Lenvatinib (Lenvima)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Ruxolitinib|Ruxolitinib (Jakafi)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
===== mTOR Inhibitors =====
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Everolimus|Everolimus (Afinitor)]]


===== Photosensitizing agents =====
===== Photosensitizing agents =====
* [[Aminolevulinic acid |Aminolevulinic acid (Levulan)]]
* [[Aminolevulinic acid |Aminolevulinic acid (Levulan)]]
* [[Porfimer|Porfimer (Photofrin)]]


===== Proteasome inhibitors =====
===== Proteasome inhibitors =====
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===== Somatostatin analogs =====
===== Somatostatin analogs =====
* [[Octreotide|Octreotide (Octreotide)]]
* [[Octreotide|Octreotide (Octreotide)]]
===== VEGF receptor-2 antagonists =====
* [[Ramucirumab|Ramucirumab (Cyramza)]]


===== Differentiating agents =====
===== Differentiating agents =====
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* [[Bexarotene|Bexarotene (Targretin)]]
* [[Bexarotene|Bexarotene (Targretin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
===== Orphan drugs =====
* [[Olaparib|Olaparib (Lynparza)]]
* [[Omacetaxine|Omacetaxine (Synribo)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Trabectedin|Trabectedin (Yondelis)]]


== Chemotherapeutic Agents in Alphabetical Order ==
== Chemotherapeutic Agents in Alphabetical Order ==
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* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Trilostane|Trilostane (Vetoryl)]]
* [[Trilostane|Trilostane (Modrenal)]]
* [[Triptorelin pamoate|Triptorelin pamoate (Trelstar)]]
* [[Triptorelin pamoate|Triptorelin pamoate (Trelstar)]]
* [[Valrubicin|Valrubicin (Valstar)]]
* [[Valrubicin|Valrubicin (Valstar)]]

Latest revision as of 04:08, 22 March 2015

Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]

Overview

This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).

Chemotherapeutic Agents by Category

Alkylating agents

Nitrogen mustards
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes

Antimetabolites

Folic acid analogs
Pyrimidine analogs
Purine analogs
Ribonucleotide reductase inhibitors

Natural products

Vinca alkaloids
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
Antineoplastic enzymes

Hormones and Antagonists

Adrenocortical suppressants
Glucocorticoids
Progestins
Estrogens
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
LHRH agonists
GnRH agonists
GnRH antagonists

Biologics

Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-6 inhibitors
Immunotherapy

Hematopoietic Growth Factors

Erythrocyte growth factors
Granulocyte growth factors
Megakaryocyte growth factors

Supportive Medications

Chemotherapy protective agents
Antiemetic agents
RANK ligand inhibitors
Calcium regulators

Miscellaneous

Mitotic inhibitors
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Orphan drugs

Chemotherapeutic Agents in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
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