Sepsis causes: Difference between revisions
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*[[Vibrio vulnificus]] | *[[Vibrio vulnificus]] | ||
==Microbes== | ==Microbes== | ||
Common organisms responsible for sepsis includes: | Common organisms responsible for sepsis includes:<ref name="pmid12851245">{{cite journal |vauthors=Annane D, Aegerter P, Jars-Guincestre MC, Guidet B |title=Current epidemiology of septic shock: the CUB-Réa Network |journal=Am. J. Respir. Crit. Care Med. |volume=168 |issue=2 |pages=165–72 |year=2003 |pmid=12851245 |doi=10.1164/rccm.2201087 |url=}}</ref><ref name="pmid17192537">{{cite journal |vauthors=Pronovost P, Needham D, Berenholtz S, Sinopoli D, Chu H, Cosgrove S, Sexton B, Hyzy R, Welsh R, Roth G, Bander J, Kepros J, Goeschel C |title=An intervention to decrease catheter-related bloodstream infections in the ICU |journal=N. Engl. J. Med. |volume=355 |issue=26 |pages=2725–32 |year=2006 |pmid=17192537 |doi=10.1056/NEJMoa061115 |url=}}</ref> | ||
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!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Aerobic bacteria}} | !colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Aerobic bacteria}} | ||
Revision as of 17:22, 22 May 2017
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Resident Survival Guide |
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Sepsis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Sepsis causes On the Web |
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American Roentgen Ray Society Images of Sepsis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]
Synonyms and keywords: sepsis syndrome; septic shock; septicemia
Overview
The process of infection by bacteria or fungi can result in systemic signs and symptoms that are variously described. In rough order of severity, these are bacteremia or fungemia; septicemia; sepsis, severe sepsis or sepsis syndrome; septic shock; refractory septic shock; multiple organ dysfunction syndrome, and death. The condition develops as a response to certain microbial molecules which trigger the production and release of cellular mediators, such as tumor necrosis factors (TNF); these act to stimulate immune response.
Causes
Life Threatening Causes
Common Causes
Sepsis is caused by a bacterial infection that can begin anywhere in the body. Common places where an infection might start include:
- The bowel (usually seen with peritonitis)
- The kidneys (upper urinary tract infection or pyelonephritis)
- The lining of the brain (meningitis)
- The liver or the gall bladder (cholecystitis)
- The lungs (bacterial pneumonia)
- The skin (cellulitis)
- In children, sepsis may accompany infection of the bone (osteomyelitis).
- In hospitalized patients, common sites of infection include intravenous lines, surgical wounds, surgical drains, and sites of skin breakdown known as bedsores (decubitus ulcers).
Causes by Organ System
| Cardiovascular | Acute bacterial endocarditis, myocardial ring abscess, subacute bacterial endocarditis |
| Chemical / poisoning | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Aldesleukin,Aprotinin, Boceprevir, Caspofungin acetate, Ceritinib, Crizotinib, Cytarabine, Dactinomycin, Doxorubicin Hydrochloride, Felbamate, Ixabepilone, Meropenem, Mitomycin, Oxaprozin, Pergolide, Pralatrexate, , Pramipexole, Sargramostim, Sipuleucel-T, Sirolimus, Strontium chloride, Tiagabine, Tocilizumab, Vedolizumab |
| Ear Nose Throat | Bronchitis, otitis media, pharyngitis, sinusitis |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | Abscess, Bicalutamide, esophagitis, gastritis, gastrointestinal bleeding, instrumentation, intestinal obstruction, pancreatitis, small intestine disorder |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal / Ortho | Osteomyelitis, wound infections |
| Neurologic | Acute bacterial meningitis |
| Nutritional / Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Opthalmologic | No underlying causes |
| Overdose / Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | Community-acquired pneumonia, empyema, lung abscess |
| Renal / Electrolyte | Acute prostatitis/abscess, catheter-associated bacteriuria, cervicitis, chronic kidney disease, cystitis, instrumentation, intranephric abscess or perinephric abscess, pyelonephritis, renal calculi, urethritis, urinary tract obstruction, vaginitis |
| Rheum / Immune / Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
- Cytarabine
- Doxorubicin Hydrochloride
- Gangrene
- Gram negative bacteremia
- Ixabepilone
- Lemierre syndrome
- Melioidosis
- Necrotizing enterocolitis
- Neisseria meningiditis
- Oxaprozin
- Pergolide
- Peritonitis
- Pralatrexate,
- Pseudomonas aeruginosa
- Sargramostim
- Sipuleucel-T
- Tiagabine
- Vibrio vulnificus
Microbes
Common organisms responsible for sepsis includes:[1][2]
| Aerobic bacteria | Anaerobes bacteria | Fungal | Parasite |
|---|---|---|---|
References
- ↑ Annane D, Aegerter P, Jars-Guincestre MC, Guidet B (2003). "Current epidemiology of septic shock: the CUB-Réa Network". Am. J. Respir. Crit. Care Med. 168 (2): 165–72. doi:10.1164/rccm.2201087. PMID 12851245.
- ↑ Pronovost P, Needham D, Berenholtz S, Sinopoli D, Chu H, Cosgrove S, Sexton B, Hyzy R, Welsh R, Roth G, Bander J, Kepros J, Goeschel C (2006). "An intervention to decrease catheter-related bloodstream infections in the ICU". N. Engl. J. Med. 355 (26): 2725–32. doi:10.1056/NEJMoa061115. PMID 17192537.