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{{Lymphadenopathy}}
{{Lymphadenopathy}}
{{CMG}}; {{AE}}{{ADS}}{{RT}}
{{CMG}}; {{AE}}{{ADS}}{{RT}}{{DYM}} [[Ogechukwu Hannah Nnabude, MD]]
==Overview==
==Overview==


Common risk factors in the development of [[lymphadenopathy]] include people at risk of infections as seen in high-risk sexual behavior for [[HIV]],[[Cytomegalovirus]], [[IV]] [[drug users]], recent [[blood transfusion]].
Common risk factors in the development of [[lymphadenopathy]] include people at risk of infections as seen in high-risk sexual behavior for [[HIV]],[[Cytomegalovirus]], [[IV]] [[drug users]], recent [[blood transfusion]]. [[HIV]] is a [[lymphotropic]] [[virus]] that activates [[lymph node]] remodeling. [[Lymph nodes]] that clinically manifest as persistent at a pathological stage Three distinct stages of [[lymphadenopathy]] include stage I, explosive follicular disease  [[Big germinal]] centers of [[hyperplasia]],  stage II, [[germinal]] centers  depletion of [[lymphocytes]] and central involution, and step III, [[proliferation]]  Within the [[lymph nodes]], [[blood vessels]]


==Risk Factors==
==Risk Factors==
===Common Risk Factors===
===Common Risk Factors===
*Common risk factors in the development of lymphadenopathy may be occupational, environmental, genetic, and viral.
 
*Common risk factors in the development of lymphadenopathy include:<ref name="pmid30020622">{{cite journal |vauthors=Freeman AM, Matto P |title= |journal= |volume= |issue= |pages= |date= |pmid=30020622 |doi= |url=}}</ref>
*Common risk factors in the development of [[lymphadenopathy]] may be occupational, environmental, [[genetic]], and [[viral]].<ref name="pmid30020622">{{cite journal |vauthors=Freeman AM, Matto P |title= |journal= |volume= |issue= |pages= |date= |pmid=30020622 |doi= |url=}}</ref><ref name="pmid33325733">{{cite journal |vauthors=Glushko T, He L, McNamee W, Babu AS, Simpson SA |title=HIV Lymphadenopathy: Differential Diagnosis and Important Imaging Features |journal=AJR Am J Roentgenol |volume=216 |issue=2 |pages=526–533 |date=February 2021 |pmid=33325733 |doi=10.2214/AJR.19.22334 |url=}}</ref><ref name="pmid22805116">{{cite journal |vauthors=Bogoch II, Andrews JR, Nagami EH, Rivera AM, Gandhi RT, Stone D |title=Clinical predictors for the aetiology of peripheral lymphadenopathy in HIV-infected adults |journal=HIV Med |volume=14 |issue=3 |pages=182–6 |date=March 2013 |pmid=22805116 |pmc=3562378 |doi=10.1111/j.1468-1293.2012.01035.x |url=}}</ref>
** High risk sexual behaviour - [[HIV]]/[[AIDS]], [[Hepatitis B]], [[Herpes simplex]], [[Cytomegalovirus]]
*Common risk factors in the development of lymphadenopathy include:
** I.V drug abuse- [[HIV]]/ [[AIDS]], [[Hepatitis B]], [[Endocarditis]]
**High risk sexual behaviour - [[HIV]]/[[AIDS]], [[Hepatitis B]], [[Herpes simplex]], [[Cytomegalovirus]]
** Local soft-tissue infections
**I.V drug abuse- [[HIV]]/ [[AIDS]], [[Hepatitis B]], [[Endocarditis]]
**Local soft-tissue infections
**[[Upper respiratory tract infection]]
**[[Upper respiratory tract infection]]


===Less Common Risk Factors===
===Less Common Risk Factors===
*Less common risk factors in the development of lymphadenopathy include:
*Less common risk factors in the development of lymphadenopathy include:
**Recent [[blood transfusion]]- [[Cytomegalovirus]], [[HIV]]/ [[AIDS]]
**Recent [[blood transfusion]]- [[Cytomegalovirus]], [[HIV]]/ [[AIDS]]
** Eating under cooked meat- [[Toxoplasmosis]]
**Eating under cooked meat- [[Toxoplasmosis]]
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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Latest revision as of 05:16, 9 December 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]Raviteja Guddeti, M.B.B.S. [3]Delband Yekta Moazami, M.D.[4] Ogechukwu Hannah Nnabude, MD

Overview

Common risk factors in the development of lymphadenopathy include people at risk of infections as seen in high-risk sexual behavior for HIV,Cytomegalovirus, IV drug users, recent blood transfusion. HIV is a lymphotropic virus that activates lymph node remodeling. Lymph nodes that clinically manifest as persistent at a pathological stage Three distinct stages of lymphadenopathy include stage I, explosive follicular disease Big germinal centers of hyperplasia, stage II, germinal centers depletion of lymphocytes and central involution, and step III, proliferation Within the lymph nodes, blood vessels

Risk Factors

Common Risk Factors

Less Common Risk Factors

References

  1. Freeman AM, Matto P. PMID 30020622. Missing or empty |title= (help)
  2. Glushko T, He L, McNamee W, Babu AS, Simpson SA (February 2021). "HIV Lymphadenopathy: Differential Diagnosis and Important Imaging Features". AJR Am J Roentgenol. 216 (2): 526–533. doi:10.2214/AJR.19.22334. PMID 33325733 Check |pmid= value (help).
  3. Bogoch II, Andrews JR, Nagami EH, Rivera AM, Gandhi RT, Stone D (March 2013). "Clinical predictors for the aetiology of peripheral lymphadenopathy in HIV-infected adults". HIV Med. 14 (3): 182–6. doi:10.1111/j.1468-1293.2012.01035.x. PMC 3562378. PMID 22805116.

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