Lymphadenopathy CT scan

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Lymphadenopathy Microchapters


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Historical Perspective




Differentiating Lymphadenopathy from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


Diagnostic Criteria

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2] Ogechukwu Hannah Nnabude, MD


A chest CT scan may be helpful in the diagnosis of hilar adenopathy. Findings on CT scan diagnostic of tuberculosis, sarcoidosis, lymphoma, and other malignancies. Abdominal and pelvic CT scan in combination with chest CT scan can be revealed in cases of supraclavicular adenopathy and the diagnosis of secondary neoplasm.

CT scan

  • CT scan may be helpful in the diagnosis of lymphadenopathy. Findings on CT scan suggestive of lymphadenopathy include:[1][2][3][4]
  • The upper limit in the size of a normal node varies with location.

PET/CT scan

  • On PET/CT scan, lymphadenopathy can be further assessed via quantitation of FDG uptake, which is a surrogate of metabolic activity. Infectious, inflammatory, and neoplastic processes will show high FDG avidity. PET/CT is particularly useful for assessing the response of lymph nodes to systemic chemotherapy.


  1. Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.
  2. Lymph node enlargment. Radiopedia. Accessed on May 9, 2016
  3. van den Brekel MW, Castelijns JA (January 2000). "Imaging of lymph nodes in the neck". Semin Roentgenol. 35 (1): 42–53. PMID 10670052.
  4. Sumi M, Ohki M, Nakamura T (April 2001). "Comparison of sonography and CT for differentiating benign from malignant cervical lymph nodes in patients with squamous cell carcinoma of the head and neck". AJR Am J Roentgenol. 176 (4): 1019–24. doi:10.2214/ajr.176.4.1761019. PMID 11264102.

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