Lymphadenopathy risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]Raviteja Guddeti, M.B.B.S. [3]Delband Yekta Moazami, M.D.[4] Ogechukwu Hannah Nnabude, MD


Common risk factors in the development of lymphadenopathy include people at risk of infections as seen in high-risk sexual behavior for HIV,Cytomegalovirus, IV drug users, recent blood transfusion. HIV is a lymphotropic virus that activates lymph node remodeling. Lymph nodes that clinically manifest as persistent at a pathological stage Three distinct stages of lymphadenopathy include stage I, explosive follicular disease Big germinal centers of hyperplasia, stage II, germinal centers depletion of lymphocytes and central involution, and step III, proliferation Within the lymph nodes, blood vessels

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  1. Freeman AM, Matto P. PMID 30020622. Missing or empty |title= (help)
  2. Glushko T, He L, McNamee W, Babu AS, Simpson SA (February 2021). "HIV Lymphadenopathy: Differential Diagnosis and Important Imaging Features". AJR Am J Roentgenol. 216 (2): 526–533. doi:10.2214/AJR.19.22334. PMID 33325733 Check |pmid= value (help).
  3. Bogoch II, Andrews JR, Nagami EH, Rivera AM, Gandhi RT, Stone D (March 2013). "Clinical predictors for the aetiology of peripheral lymphadenopathy in HIV-infected adults". HIV Med. 14 (3): 182–6. doi:10.1111/j.1468-1293.2012.01035.x. PMC 3562378. PMID 22805116.

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