Nephrotoxic drugs

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aarti Narayan, M.B.B.S [3]

Overview

Nephrotoxic drugs are pharmacotherapies that can lead to a decline in renal function. The drug may need to be discontinued, or the dosing reduced when this happens.

Common Nephrotoxic drugs

Antibiotics

Antibacterials

  • Occurs in 10-20% patients on 7 day course
  • Results in non-oligurics; increased creatinine
  • A single dose early in septic course is usually safe

Antivirals

Antiparasitic drugs

Chemotherapy and Immunosuppressants

Heavy Metals and Poisons

AntiHyperlipidemics

Chemotherapy

Proton channel blockers

Miscellaneous Drugs

Drugs of abuse

References


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