Troponin I

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WikiDoc Resources for Troponin I
Articles
Most recent articles on Troponin I Most cited articles on Troponin I Review articles on Troponin I Articles on Troponin I in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Troponin I Images of Troponin I Photos of Troponin I Podcasts & MP3s on Troponin I Videos on Troponin I
Evidence Based Medicine
Cochrane Collaboration on Troponin I Bandolier on Troponin I TRIP on Troponin I
Clinical Trials
Ongoing Trials on Troponin I at Clinical Trials.gov Trial results on Troponin I Clinical Trials on Troponin I at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Troponin I NICE Guidance on Troponin I NHS PRODIGY Guidance FDA on Troponin I CDC on Troponin I
Books
Books on Troponin I
News
Troponin I in the news Be alerted to news on Troponin I News trends on Troponin I
Commentary
Blogs on Troponin I
Definitions
Definitions of Troponin I
Patient Resources / Community
Patient resources on Troponin I Discussion groups on Troponin I Patient Handouts on Troponin I Directions to Hospitals Treating Troponin I Risk calculators and risk factors for Troponin I
Healthcare Provider Resources
Symptoms of Troponin I Causes & Risk Factors for Troponin I Diagnostic studies for Troponin I Treatment of Troponin I
Continuing Medical Education (CME)
CME Programs on Troponin I
International
Troponin I en Espanol Troponin I en Francais
Businness
Troponin I in the Marketplace Patents on Troponin I
Experimental / Informatics
List of terms related to Troponin I

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Overview

Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the troponin-tropomyosin complex in place. The letter I is given due to its inhibitory character.

The tissue specific subtypes are:

• Slow-twitch skeletal muscle isoform troponin I, TNNI1 (1q31.3, 191042)
• Fast-twitch skeletal muscle isoform troponin I, TNNI2 (11p15.5, 191043)
• Cardiac troponin I, TNNI3 (19q13.4, 191044)

External links

• MeSH Troponin+I

v • d • e Histology: muscle tissue
skeletal muscle/general	epimysium, fascicle, perimysium, endomysium, muscle fiber (intrafusal, extrafusal), myofibril sarcomere (a, i, and h bands; z and m lines), myofilaments (thin filament/actin, thick filament/myosin, elastic filament/titin, nebulin), tropomyosin, troponin (T, C, I) costamere (dystrophin, α,β-dystrobrevin, syncoilin, synemin/desmuslin, dysbindin, sarcoglycan, dystroglycan, sarcospan), desmin neuromuscular junction, motor unit, muscle spindle, excitation-contraction coupling, sliding filament mechanism myoblast, satellite cell, sarcoplasm, sarcolemma, sarcoplasmic reticulum, T-tubule
cardiac muscle	myocardium, intercalated disc, nebulette
smooth muscle	calmodulin, vascular smooth muscle

v • d • e Electrocardiography
Overview	History of the EKG • EKG interpretation basics • Normal sinus rhythm
EKG Complexes	P wave • QRS complex • ST Segment • T wave • U wave Osborn wave • H wave • K wave • Delta wave NSSTW changes
EKG Intervals	PR Interval • QRS Interval • ST Interval • QT Interval
Conduction System & Bradycardia	Cardiac pacemaker • SA node • AV node• Bundle of His • Purkinje fibers • Sinus bradycardia • First Degree AV Block • Second Degree AV Block • Complete or Third-Degree AV Block • Concealed conduction • AV Junctional Rhythms • LBBB • LAHB • LPHB • RBBB • Trifascicular block
Atrial Arrhythmias	Sinus tachycardia • Premature Atrial Contractions (PACs) • Ectopic Atrial Rhythm • Paroxysmal Atrial Tachycardia (PAT) • Paroxysmal Atrial Tachycardia (PAT) with Block • Multifocal Atrial Tachycardia (MAT) • Atrial Flutter • Atrial Fibrillation • Wandering atrial pacemaker
Ventricular Arrhythmias	Differential Diagnosis of Tachycardia with a Wide QRS Complex • Accelerated Idioventricular Rhythm • Ventricular Parasystole • Premature Ventricular Contractions (PVCs) • Ventricular tachycardia • Ventricular Fibrillation • Sudden cardiac death
EKG Abnormalities in Disease States	Hypertrophy & Dilatation • Right atrial enlargement • Left atrial enlargement • Biatrial enlargement • Left Ventricular Hypertrophy • Right Ventricular Hypertrophy • Biventricular Hypertrophy • Acute myocardial infarction • NSTEMI • STEMI • Right ventricular myocardial infarction • Atrial infarction Pre-excitation Syndromes • Wolff-Parkinson-White Syndrome • Lown Ganong Levine Syndrome • Mahaim Type Preexcitation Cardiomyopathies • Arrhythmogenic Right Ventricular Dysplasia • Dilated Cardiomyopathy • Hypertrophic Cardiomyopathy Drug Effects on the EKG • Adenosine • β-blockers • Digitalis • Quinidine • Procainamide • Disopyramide • Lidocaine • Tocainide and Mexiletine • Phenytoin • Encainide, Flecainide and Propafenone • Amiodarone • Bretylium • Ca Channel Blockers • Phenothiazines • Tricyclic Antidepressants • Lithium Congenital Heart Disease • Dextrocardia • Atrial Septal Defect • Ventricular Septal Defect • Tetralogy of Fallot • Conjoined Twins or Siamese Twins Electrolyte Disturbances • Hyperkalemia • Hypokalemia • Hypercalcemia • Hypocalcemia • Nonspecific Changes Other Heart Diseases • Pericarditis • Myocarditis • Tamponade • Heart Transplantation • Sick Sinus Syndrome • Long QT Syndrome Inherited Disease • Brugada Syndrome Systemic Diseases • CNS Disease • Cardiac Tumors Heart Transplantation • EKG Changes in patient with Heart Transplantation Exogenous Effects • Hypothermia • Chest Trauma • Insect Bites • Electric Injuries
Technical Issues and Potential Errors in Interpretation	Artifacts • Lead Placement Errors • The EKG in a Patient with a Pacemaker

v • d • e Circulatory system pathology (I, 390-459)
Hypertension	Hypertensive heart disease - Hypertensive nephropathy - Secondary hypertension (Renovascular hypertension)
Ischaemic heart disease	Angina pectoris (Prinzmetal's angina) - Myocardial infarction (heart attack) - Dressler's syndrome
Pulmonary circulation	Pulmonary embolism - Cor pulmonale
Pericardium	Pericarditis - Pericardial effusion - Cardiac tamponade
Endocardium/heart valves	Endocarditis - mitral valve (regurgitation, prolapse, stenosis) - aortic valve (stenosis, insufficiency) - pulmonary valve (stenosis, insufficiency) - tricuspid valve (stenosis, insufficiency)
Myocardium	Myocarditis - Cardiomyopathy (Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Loeffler endocarditis, Restrictive cardiomyopathy) - Arrhythmogenic right ventricular dysplasia
Electrical conduction system of the heart	Heart block: AV block (First degree, Second degree, Third degree) - Bundle branch block (Left, Right) - Bifascicular block - Trifascicular block Pre-excitation syndrome (Wolff-Parkinson-White, Lown-Ganong-Levine) - Long QT syndrome - Adams-Stokes syndrome - Cardiac arrest - Sudden cardiac death Arrhythmia: Paroxysmal tachycardia (Supraventricular, AV nodal reentrant, Ventricular) - Atrial flutter - Atrial fibrillation (Familial) - Ventricular fibrillation - Premature contraction (Atrial, Ventricular) - Ectopic pacemaker - Sick sinus syndrome
Other heart conditions	Heart failure - Cardiovascular disease - Cardiomegaly - Ventricular hypertrophy (Left, Right)
Cerebrovascular diseases	Stroke - Transient ischemic attack - Intracranial hemorrhage/cerebral hemorrhage: Extra-axial hemorrhage (Epidural hemorrhage, Subdural hemorrhage, Subarachnoid hemorrhage) Intra-axial hematoma (Intraventricular hemorrhages, Intraparenchymal hemorrhage) - Anterior spinal artery syndrome - Binswanger's disease - Moyamoya disease
Arteries, arterioles and capillaries	Atherosclerosis (Renal artery stenosis) - Aortic dissection/Aortic aneurysm (Abdominal aortic aneurysm) - Aneurysm - Raynaud's phenomenon/Raynaud's disease - Buerger's disease - Vasculitis/Arteritis (Aortitis) - Intermittent claudication - Arteriovenous fistula - Hereditary hemorrhagic telangiectasia - Spider angioma - Dissection (Carotid artery, Vertebral artery)
Veins, lymphatic vessels and lymph nodes	Thrombosis/Phlebitis/Thrombophlebitis (Deep vein thrombosis, May-Thurner syndrome, Portal vein thrombosis, Venous thrombosis, Budd-Chiari syndrome, Renal vein thrombosis, Paget-Schroetter disease) - Varicose veins / Portacaval anastomosis (Hemorrhoid, Esophageal varices, Varicocele, Gastric varices, Caput medusae) - Superior vena cava syndrome - Lymph (Lymphadenitis, Lymphedema, Lymphangitis)
Other	Hypotension (Orthostatic hypotension) - Rheumatic fever
See also congenital (Q20-Q28, 745-747)

v • d • e WikiDoc Research Resources for Troponin I
Articles on Troponin I	Most recent articles on Troponin I • Most cited articles on Troponin I • Review articles on Troponin I • Articles on Troponin I in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Troponin I	Powerpoint slides on Troponin I • Images of Troponin I • Photos of Troponin I • Podcasts & MP3s on Troponin I • Videos on Troponin I
Evidence Based Medicine Regarding Troponin I	Cochrane Collaboration on Troponin I • Bandolier on Troponin I • TRIP on Troponin I
Cost Effectiveness of Troponin I	Cost Effectiveness of Troponin I
Clinical Trials Involving Troponin I	Ongoing Trials on Troponin I at Clinical Trials.gov • Trial results on Troponin I • Clinical Trials on Troponin I at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Troponin I	US National Guidelines Clearinghouse on Troponin I • NICE Guidance on Troponin I • NHS PRODIGY Guidance • FDA on Troponin I • CDC on Troponin I
Textbook Information on Troponin I	Books and Textbook Information on Troponin I
Pharmacology Resources on Troponin I	Dosing of Troponin I • Drug interactions with Troponin I • Side effects of Troponin I • Allergic reactions to Troponin I • Overdose information on Troponin I • Carcinogenicity information on Troponin I • Troponin I in pregnancy • Pharmacokinetics of Troponin I •
Genetics, Pharmacogenomics, and Proteinomics of Troponin I	Genetics of Troponin I • Pharmacogenomics of Troponin I • Proteomics of Troponin I
Newstories on Troponin I	Troponin I in the news • Be alerted to news on Troponin I • News trends on Troponin I
Commentary on Troponin I	Blogs on Troponin I
Patient Resources on Troponin I	Patient resources on Troponin I • Discussion groups on Troponin I • Patient Handouts on Troponin I • Directions to Hospitals Treating Troponin I • Risk calculators and risk factors for Troponin I
Healthcare Provider Resources on Troponin I	Symptoms of Troponin I • Causes & Risk Factors for Troponin I • Diagnostic studies for Troponin I • Treatment of Troponin I
Continuing Medical Education (CME) Programs on Troponin I	CME Programs on Troponin I
International Resources on Troponin I	Troponin I en Espanol • Troponin I en Francais
Business Resources on Troponin I	Troponin I in the Marketplace • Patents on Troponin I
Informatics Resources on Troponin I	List of terms related to Troponin I

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .