Adrenocortical carcinoma historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]

Overview

In 1893, Grawitz et al was the first one who described adrenocortical carcinoma (ACC) and falsely assumed that it was hypernephroma. By 1938, the Mayo group had removed tumors successfully from 16 consecutive patients, most of whom had Cushing’s syndrome. In 1960, mitotane was first used clinically to treat inoperable or recurrent ACC.

Historical perspective

References

  1. Welbourn RB (1996). "Highlights from endocrine surgical history.". World J Surg. 20 (5): 603–12. PMID 8661638. 
  2. Walters W, Wilder RM, Kepler EJ (1934). "THE SUPRARENAL CORTICAL SYNDROME WITH PRESENTATION OF TEN CASES.". Ann Surg. 100 (4): 670–88. PMC 1390421Freely accessible. PMID 17856387. 
  3. Klammer A, Morger R (1983). "Successful treatment of an adrenocortical carcinoma.". Prog Pediatr Surg. 16: 117–20. PMID 6878723. 
  4. RAPAPORT E, GOLDBERG MB, GORDAN GS, HINMAN F (1952). "Mortality in surgically treated adrenocortical tumors. II. Review of cases reported for the 20 year period 1930-1949, inclusive.". Postgrad Med. 11 (4): 325–53. PMID 14920312. 
  5. MACFARLANE DA (1958). "Cancer of the adrenal cortex; the natural history, prognosis and treatment in a study of fifty-five cases.". Ann R Coll Surg Engl. 23 (3): 155–86. PMC 2413691Freely accessible. PMID 13571886. 

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