Hex sequence gene transcriptions

Associate Editor(s)-in-Chief: Henry A. Hoff

Human genes

Consensus sequences

The Hex sequence has the consensus (TGACGTGGC)^[1]

Hypotheses

A1BG has no Hex sequences in either promoter.
A1BG is not transcribed by a Hex sequence.
No Hex sequence participates in the transcription of A1BG.

Samplings

Copying a responsive elements consensus sequence TGACGTGGC and putting the sequence in "⌘F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence TGACGTGGC (starting with SuccessablesHex.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for TGACGTGGC, 0.
negative strand, positive direction, looking for TGACGTGGC, 0.
positive strand, negative direction, looking for TGACGTGGC, 0.
positive strand, positive direction, looking for TGACGTGGC, 1, TGACGTGGC at 4344.
complement, negative strand, negative direction, looking for ACTGCACCG, 0.
complement, negative strand, positive direction, looking for ACTGCACCG, 1, ACTGCACCG at 4344.
complement, positive strand, negative direction, looking for ACTGCACCG, 0.
complement, positive strand, positive direction, looking for ACTGCACCG, 0.
inverse complement, negative strand, negative direction, looking for TTTTTTTT, 0.
inverse complement, negative strand, positive direction, looking for TTTTTTTT, 0.
inverse complement, positive strand, negative direction, looking for TTTTTTTT, 0.
inverse complement, positive strand, positive direction, looking for TTTTTTTT, 0.
inverse negative strand, negative direction, looking for AAAAAAAA, 0.
inverse negative strand, positive direction, looking for AAAAAAAA, 0.
inverse positive strand, negative direction, looking for AAAAAAAA, 0.
inverse positive strand, positive direction, looking for AAAAAAAA, 0.

Hex core promoters

Positive strand: TGACGTGGC at 4344, and complement.

Hex proximal promoters

Hex distal promoters

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

References

↑ Young Hun Song; Cheol Min Yoo; An Pio Hong; Seong Hee Kim; Hee Jeong Jeong; Su Young Shin; Hye Jin Kim; Dae-Jin Yun; Chae Oh Lim; Jeong Dong Bahk; Sang Yeol Lee; Ron T. Nagao; Joe L. Key; Jong Chan Hong (April 2008). "DNA-Binding Study Identifies C-Box and Hybrid C/G-Box or C/A-Box Motifs as High-Affinity Binding Sites for STF1 and LONG HYPOCOTYL5 Proteins" (PDF). Plant Physiology. 146 (4): 1862–1877. doi:10.1104/pp.107.113217. PMID 18287490. Retrieved 26 March 2019.

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