Myelocytomatosis transcription factor gene transcriptions

Associate Editor(s)-in-Chief: Henry A. Hoff

L-myc-1 proto-oncogene protein is a protein that in humans is encoded by the MYCL1 gene.^[1]^[2]

MYCL1 is a bHLH (basic helix-loop-helix) transcription factor implicated in lung cancer.^[3]

Human genes

Gene ID: 4609 is MYC proto-oncogene, bHLH transcription factor: "This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes."^[4]

Interactions

MYCL1 has been shown to interact with MAX.^[5]^[6]

Consensus sequences

Samplings

References

↑ Speleman F, Van Camp G, Van Roy N (January 1997). "Reassignment of MYCL1 to human chromosome 1p34.3 by fluorescence in situ hybridization". Cytogenet Cell Genet. 72 (2–3): 189–190. doi:10.1159/000134185. PMID 8978772.
↑ "Entrez Gene: MYCL1 v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)".
↑ Ikegaki N, Minna J, Kennett RH (1989). "The human L-myc gene is expressed as two forms of protein in small cell lung carcinoma cell lines: detection by monoclonal antibodies specific to two myc homology box sequences". EMBO J. 8 (6): 1793–9. doi:10.1002/j.1460-2075.1989.tb03573.x. PMC 401025. PMID 2548855.
↑ RefSeq (August 2017). "MYC MYC proto-oncogene, bHLH transcription factor [ Homo sapiens (human) ]". 8600 Rockville Pike, Bethesda MD, 20894 USA: National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved 29 August 2020.
↑ Blackwood EM, Eisenman RN (March 1991). "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc". Science. 251 (4998): 1211–1217. Bibcode:1991Sci...251.1211B. doi:10.1126/science.2006410. PMID 2006410.
↑ FitzGerald MJ, Arsura M, Bellas RE, Yang W, Wu M, Chin L, Mann KK, DePinho RA, Sonenshein GE (Apr 1999). "Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc". Oncogene. 18 (15): 2489–2498. doi:10.1038/sj.onc.1202611. PMID 10229200.

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transcriptions MYB recognition element gene transcriptions Myelocytomatosis transcription factor gene transcriptions Myocyte enhancer factor gene transcriptions N-boxes Ndt80p gene transcriptions Nuclear factor 1 Nuclear factor 𝜿B Nuclear factor gene transcriptions Nuclear factor of activated T cell gene transcriptions (NFAT) Nuclear factor Y gene transcriptions Nutrient-sensing response element gene transcriptions Oaf1p gene transcriptions ORE1 binding site gene transcriptions p53 response element gene transcriptions P63 DNA-binding site gene transcriptions P box gene transcriptions Pdr1,3p gene transcriptions Peroxisome proliferator hormone response element gene transcriptions Phosphate starvation-response transcription factor gene transcriptions Pollen1 element gene transcriptions Polycomb response element gene transcriptions Preinitiation complex Preinitiation complex gene transcriptions Pribnow box gene transcriptions Prolamin box gene transcriptions Promoter gene transcriptions 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transcriptions Ste12p gene transcriptions Sterol response element gene transcriptions Sucrose box gene transcriptions Synaptic Activity-Responsive Elements TACTAAC box gene transcriptions TAGteam gene transcriptions Tapetum box gene transcriptions TATA binding protein associated factor gene transcriptions TATA binding protein gene transcriptions TATA box gene transcriptions TAT box gene transcriptions TATC box gene transcriptions Tbf1 regulatory factor gene transcriptions T box gene transcriptions TCCACCATA element gene transcriptions TC element gene transcriptions TCT gene transcriptions TEA consensus sequence gene transcriptions Tec1p gene transcriptions Telomeric repeat DNA-binding factor gene transcriptions Tetradecanoylphorbol-13-acetate response element gene transcriptions TGF-β control elements (TCEs) TGF-β inhibitory elements (TIEs) Thyroid hormone response element gene transcriptions Transcriptional regulation Transcription bubble gene transcriptions Transcription factor gene 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