Carbon source-responsive element gene transcriptions: Difference between revisions

Associate Editor(s)-in-Chief: Henry A. Hoff

"Deletion analysis of the ICL1 promoter led to the identification of an upstream activating sequence element, UASICL1 (5' CATTCATCCG 3'), necessary and sufficient for conferring carbon source-dependent regulation on a heterologous reporter gene. Similar sequence motifs were also found in the upstream regions of coregulated genes involved in gluconeogenesis. This carbon source-responsive element (CSRE) interacts with a protein factor, designated Ang1 (activator of nonfermentative growth), detectable only in extracts derived from derepressed cells."^[1]

"Carbon source-responsive element (CSRE) are bound by the transcriptional activators Sip4 and Cat8 to induce the expression of gluconeogenesis genes in S. cerevisiae (Hiesinger, Roth, Meissner, & Schuller, 2001)."^[2]

CSRE samplings

Copying a responsive elements consensus sequence CATTCATCCG and putting the sequence in "⌘F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence CATTCATCCG (starting with SuccessablesCSRE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for CATTCATCCG, 0.
positive strand, negative direction, looking for CATTCATCCG, 0.
positive strand, positive direction, looking for CATTCATCCG, 0.
negative strand, positive direction, looking for CATTCATCCG, 0.
complement, negative strand, negative direction, looking for GTAAGTAGGC, 0.
complement, positive strand, negative direction, looking for GTAAGTAGGC, 0.
complement, positive strand, positive direction, looking for GTAAGTAGGC, 0.
complement, negative strand, positive direction, looking for GTAAGTAGGC, 0.
inverse complement, negative strand, negative direction, looking for CGGATGAATG, 0.
inverse complement, positive strand, negative direction, looking for CGGATGAATG, 0.
inverse complement, positive strand, positive direction, looking for CGGATGAATG, 0.
inverse complement, negative strand, positive direction, looking for CGGATGAATG, 0.
inverse negative strand, negative direction, looking for GCCTACTTAC, 0.
inverse positive strand, negative direction, looking for GCCTACTTAC, 0.
inverse positive strand, positive direction, looking for GCCTACTTAC, 0.
inverse negative strand, positive direction, looking for GCCTACTTAC, 0.

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

References

↑ A Schöler and H J Schüller (June 1994). "A carbon source-responsive promoter element necessary for activation of the isocitrate lyase gene ICL1 is common to genes of the gluconeogenic pathway in the yeast Saccharomyces cerevisiae" (PDF). Molecular and Cellular Biology. 14 (6): 3613–3622. Retrieved 9 February 2021.
↑ Roland Prielhofer, Michaela Reichinger, Nina Wagner, Katrien Claes, Christoph Kiziak, Brigitte Gasser, Diethard Mattanovich (17 July 2018). "Superior protein titers in half the fermentation time: Promoter and process engineering for the glucose‐regulated GTH1 promoter of Pichia pastoris". Biotechnology and Bioengineering. 115 (10): 2479–2488. doi:10.1002/bit.26800. Retrieved 29 December 2021.

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Hybrid C, T boxes Hypoxia-inducible factor gene transcriptions Hypoxia response elements I box gene transcriptions Initiator element gene transcriptions Initiator-like element gene transcriptions Inositol/choline-responsive elements Interaction gene transcriptions Interferon regulatory factors Inverse copy gene transcriptions Jasmonic acid-responsive element gene transcriptions K-boxes Kozak sequence gene transcriptions Kruppel-associated box gene transcriptions Krüppel-like factor gene transcriptions L box gene transcriptions Leu3 gene transcriptions M35 box gene transcriptions MADS box gene transcriptions Maf recognition element gene transcriptions M box gene transcriptions Mcm1 regulatory factor gene transcriptions Met31p box gene transcriptions Metal responsive element gene transcriptions Middle sporulation element gene transcriptions Mig1p gene transcriptions Model samplings Motif ten element gene transcriptions Msn2,4p gene transcriptions Musashi binding element gene transcriptions MYB recognition element gene transcriptions Myelocytomatosis transcription factor gene transcriptions Myocyte enhancer factor gene transcriptions N-boxes Ndt80p gene transcriptions Nuclear factor 1 Nuclear factor 𝜿B Nuclear factor gene transcriptions Nuclear factor of activated T cell gene transcriptions (NFAT) Nuclear factor Y gene transcriptions Nutrient-sensing response element gene transcriptions Oaf1p gene transcriptions ORE1 binding site gene transcriptions p53 response element gene transcriptions P63 DNA-binding site gene transcriptions P box gene transcriptions Pdr1,3p gene transcriptions Peroxisome proliferator hormone response element gene transcriptions Phosphate starvation-response transcription factor gene transcriptions Pollen1 element gene transcriptions Polycomb response element gene transcriptions Preinitiation complex Preinitiation complex gene transcriptions Pribnow box gene transcriptions Prolamin box gene transcriptions Promoter gene transcriptions Proximal promoter gene transcriptions Promoter occurrence gene transcriptions Pyrimidine box gene transcriptions Q element gene transcriptions Rap1 regulatory factor gene transcriptions Reb1 general regulatory factor gene transcriptions Retinoblastoma control element gene transcriptions Retinoic acid response element gene transcriptions Rgt1p gene transcriptions Rlm1p gene transcriptions RNA polymerase II gene transcriptions RNA polymerase II holoenzyme complex Root specific element gene transcriptions ROR-response element gene transcriptions Rox1p gene transcriptions Rpn4p gene transcriptions R response element gene transcriptions SARE gene transcriptions Seed-specific element gene transcriptions Serum response element gene transcriptions Servenius sequence gene transcriptions Shoot specific element gene transcriptions Sip4p gene transcriptions Smp1p gene transcriptions Sp1 gene transcriptions Spaceflight gene expressions Specificity protein gene transcriptions STAT gene transcriptions Ste12p gene transcriptions Sterol response element gene transcriptions Sucrose box gene transcriptions Synaptic Activity-Responsive Elements TACTAAC box gene transcriptions TAGteam gene transcriptions Tapetum box gene transcriptions TATA binding protein associated factor gene transcriptions TATA binding protein gene transcriptions TATA box gene transcriptions TAT box gene transcriptions TATC box gene transcriptions Tbf1 regulatory factor gene transcriptions T box gene transcriptions TCCACCATA element gene transcriptions TC element gene transcriptions TCT gene transcriptions TEA consensus sequence gene transcriptions Tec1p gene transcriptions Telomeric repeat DNA-binding factor gene transcriptions Tetradecanoylphorbol-13-acetate response element gene transcriptions TGF-β control elements (TCEs) TGF-β inhibitory elements (TIEs) Thyroid hormone response element gene transcriptions Transcriptional regulation Transcription bubble gene transcriptions Transcription factor gene transcriptions Transcription factor 3 gene transcriptions Transcription factory gene transcriptions Transcription start site gene transcriptions Translational control sequence gene transcriptions U box gene transcriptions Unfolded protein response element gene transcriptions Upstream response element gene transcriptions Upstream stimulatory factor gene transcriptions UTR promoter gene transcriptions V and P box gene transcriptions V box gene transcriptions Vhr1p gene transcriptions Vitamin D response element gene transcriptions W box gene transcriptions X box gene transcriptions Xbp1p gene transcriptions X core promoter element gene transcriptions Xenobiotic response element gene transcriptions Xenobiotic responsive element gene transcriptions Yap1p,2p gene transcriptions Y box gene transcriptions YY1 gene transcriptions Zap1p gene transcriptions Z box gene transcriptions Zinc responsive element gene transcriptions

@@ Line 15: / Line 15: @@
 |pmid=
 |accessdate=9 February 2021 }}</ref>
+"Carbon source-responsive element (CSRE) are bound by the transcriptional activators [[Sip4p gene transcriptions|Sip4]] and [[Cat8p gene transcriptions|Cat8]] to induce the expression of gluconeogenesis genes in ''S. cerevisiae'' (Hiesinger, Roth, Meissner, & Schuller, 2001)."<ref name=Prielhofer>{{ cite journal
+|author=Roland Prielhofer, Michaela Reichinger, Nina Wagner, Katrien Claes, Christoph Kiziak, Brigitte Gasser, Diethard Mattanovich
+|title=Superior protein titers in half the fermentation time: Promoter and process engineering for the glucose‐regulated ''GTH1'' promoter of ''Pichia pastoris''
+|journal=Biotechnology and Bioengineering
+|date=17 July 2018
+|volume=115
+|issue=10
+|pages=2479-2488
+|url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.26800
+|arxiv=
+|bibcode=
+|doi=10.1002/bit.26800
+|pmid=
+|accessdate=29 December 2021 }}</ref>
 ==CSRE samplings==

Carbon source-responsive element gene transcriptions: Difference between revisions

Revision as of 02:51, 30 December 2021

Contents

CSRE samplings

Acknowledgements

See also

References

External links

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