Sudden cardiac versus non-cardiac death: Difference between revisions
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==Overview== | ==Overview== | ||
*[[Sudden cardiac death]] ([[SCD]]) is a natural, rapid, unexpected [[death]] secondary to [[cardiac]] causes within an hour of [[symptom onset]] in witnessed scenarios, and within a day in unwitnessed cases <ref name="pmidhttps://doi.org/10.1093/eurheartj/ehac262">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=https://doi.org/10.1093/eurheartj/ehac262 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10 }} </ref>. | *[[Sudden cardiac death]] ([[SCD]]) is a natural, rapid, unexpected [[death]] secondary to [[cardiac]] causes within an hour of [[symptom onset]] in witnessed scenarios, and within a day in unwitnessed cases <ref name="pmidhttps://doi.org/10.1093/eurheartj/ehac262">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=https://doi.org/10.1093/eurheartj/ehac262 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10 }} </ref>. | ||
* [[Sudden cardiac arrest]] ([[SCA]] | * [[Sudden cardiac arrest]] ([[SCA]]) is the unexpected cessation of pumping [[blood]] into vital [[organs]] due to electrical disturbance in the pathway of [[sinoatrial node]] ([[SA node]]), [[atrioventricular node]] ([[AV node]]), [[His Purkinje fibers]] or [[cardiac]] pumping failure due to [[cardiogenic shock]], massive [[pulmonary thromboembolism]],[[fulminant myocarditis]], and [[ruptured left ventricular free wall]]. | ||
*Without any intervention for immediate restoration of the [[circulation]], [[biologic death]] will happen minutes to weeks after [[cardiac arrest]]. [[Sudden cardiac death]] in the United States ranges from 300,000 to 400,000 which is 50% of all causes of deaths. <ref name="pmid21513133">{{cite journal| author=Haissaguerre M, Hocini M, Sacher F, Shah A| title=[Sudden cardiac death, a major scientific challenge]. | journal=Bull Acad Natl Med | year= 2010 | volume= 194 | issue= 6 | pages= 983-93; discussion 993-5 | pmid=21513133 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21513133 }} </ref> In-hospital [[cardiac arrest]] happens in 290,000 adults every year in the United States. The most common cause of [[sudden cardiac death]] is [[coronary artery disease]] and [[atherosclerosis]]. The presence of underlying disorders such as [[malignancy]] or [[liver disease]] at the time of [[ cardiac arrest]] makes the condition worse. Patients with [[acute myocardial infarction]] and [[in-hospital cardiac arrest]] with shockable [[rhythm]] have a better prognosis. Post [[cardiopulmonary resuscitation]] state management should be focused on [[neurologic]] [[complications]], [[hemodynamic]] stability, and [[respiratory]] support. | *Without any intervention for immediate restoration of the [[circulation]], [[biologic death]] will happen minutes to weeks after [[cardiac arrest]]. [[Sudden cardiac death]] in the United States ranges from 300,000 to 400,000 which is 50% of all causes of deaths. <ref name="pmid21513133">{{cite journal| author=Haissaguerre M, Hocini M, Sacher F, Shah A| title=[Sudden cardiac death, a major scientific challenge]. | journal=Bull Acad Natl Med | year= 2010 | volume= 194 | issue= 6 | pages= 983-93; discussion 993-5 | pmid=21513133 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21513133 }} </ref> In-hospital [[cardiac arrest]] happens in 290,000 adults every year in the United States. The most common cause of [[sudden cardiac death]] is [[coronary artery disease]] and [[atherosclerosis]]. The presence of underlying disorders such as [[malignancy]] or [[liver disease]] at the time of [[ cardiac arrest]] makes the condition worse. Patients with [[acute myocardial infarction]] and [[in-hospital cardiac arrest]] with shockable [[rhythm]] have a better prognosis. Post [[cardiopulmonary resuscitation]] state management should be focused on [[neurologic]] [[complications]], [[hemodynamic]] stability, and [[respiratory]] support. | ||
Revision as of 19:00, 19 July 2023
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Edzel Lorraine Co, DMD, MD[3]
Overview
- Sudden cardiac death (SCD) is a natural, rapid, unexpected death secondary to cardiac causes within an hour of symptom onset in witnessed scenarios, and within a day in unwitnessed cases [1].
- Sudden cardiac arrest (SCA) is the unexpected cessation of pumping blood into vital organs due to electrical disturbance in the pathway of sinoatrial node (SA node), atrioventricular node (AV node), His Purkinje fibers or cardiac pumping failure due to cardiogenic shock, massive pulmonary thromboembolism,fulminant myocarditis, and ruptured left ventricular free wall.
- Without any intervention for immediate restoration of the circulation, biologic death will happen minutes to weeks after cardiac arrest. Sudden cardiac death in the United States ranges from 300,000 to 400,000 which is 50% of all causes of deaths. [2] In-hospital cardiac arrest happens in 290,000 adults every year in the United States. The most common cause of sudden cardiac death is coronary artery disease and atherosclerosis. The presence of underlying disorders such as malignancy or liver disease at the time of cardiac arrest makes the condition worse. Patients with acute myocardial infarction and in-hospital cardiac arrest with shockable rhythm have a better prognosis. Post cardiopulmonary resuscitation state management should be focused on neurologic complications, hemodynamic stability, and respiratory support.
References
- ↑ Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.1093/eurheartj/ehac262 Check
|pmid=value (help). - ↑ Haissaguerre M, Hocini M, Sacher F, Shah A (2010). "[Sudden cardiac death, a major scientific challenge]". Bull Acad Natl Med. 194 (6): 983–93, discussion 993-5. PMID 21513133.