Nephrotic syndrome risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Multiple risk factors may be involved in the nephrotic syndrome, such as family history, gender, and [[obesity]]. Also, diseases such as [[Hodgkin's lymphoma|Hodgkin lymphoma]], [[leukemia]], [[Virus|viral]] diseases | Multiple risk factors may be involved in the nephrotic syndrome, such as family history, gender, and [[obesity]]. Also, diseases such as [[Hodgkin's lymphoma|Hodgkin lymphoma]], [[leukemia]], [[Virus|viral]] diseases; and medications such as [[lithium]], [[D-penicillamine]] can be risk factors for developing different types of nephrotic syndromes. | ||
==Risk factors== | ==Risk factors== | ||
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=== Less common risk factors === | === Less common risk factors === | ||
Below conditions and toxins can be a risk factor for nephrotic syndrome<ref name="pmid12944064">{{cite journal| author=Eddy AA, Symons JM| title=Nephrotic syndrome in childhood. | journal=Lancet | year= 2003 | volume= 362 | issue= 9384 | pages= 629-39 | pmid=12944064 | doi=10.1016/S0140-6736(03)14184-0 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12944064 }}</ref> | Below conditions and toxins can be a risk factor for nephrotic syndrome<ref name="pmid12944064">{{cite journal| author=Eddy AA, Symons JM| title=Nephrotic syndrome in childhood. | journal=Lancet | year= 2003 | volume= 362 | issue= 9384 | pages= 629-39 | pmid=12944064 | doi=10.1016/S0140-6736(03)14184-0 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12944064 }}</ref> | ||
*Adaptation to [[nephron]] reduction | *Adaptation to [[nephron]] reduction | ||
*[[Amyloidosis]] | *[[Amyloidosis]] | ||
| Line 84: | Line 83: | ||
*[[Vasculitis]] | *[[Vasculitis]] | ||
*[[Viral hepatitis]] | *[[Viral hepatitis]] | ||
====Drug Induced==== | ====Drug Induced==== | ||
*[[Agalsidase beta]] | *[[Agalsidase beta]] | ||
*[[Certolizumab pegol]] | *[[Certolizumab pegol]] | ||
| Line 94: | Line 91: | ||
*[[Trimethadione]] | *[[Trimethadione]] | ||
*[[Ziv-aflibercept]] | *[[Ziv-aflibercept]] | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Medicine]] | [[Category:Medicine]] | ||
[[Category:Nephrology]] | [[Category:Nephrology]] | ||
[[Category:Urology]] | |||
[[Category:Up-To-Date]] | [[Category:Up-To-Date]] | ||
[[Category:Primary care]] | [[Category:Primary care]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
Revision as of 15:15, 13 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]
Overview
Multiple risk factors may be involved in the nephrotic syndrome, such as family history, gender, and obesity. Also, diseases such as Hodgkin lymphoma, leukemia, viral diseases; and medications such as lithium, D-penicillamine can be risk factors for developing different types of nephrotic syndromes.
Risk factors
Risk factors of nephrotic syndrome depend on the type of syndromes, as below:
Common risk factors
Risk factors of development of minimal change disease include:[1]
- Children within the Age >1 year but <8 years
- Hodgkin lymphoma
- Leukemia
- Recent viral illness
- Toxins such as mercury, gold, bee stings, fire coral exposure.
- Medication such as[2]
- Salazopyrin
- Tiopronin
- Lithium
- D-penicillamine
- Tyrosine-kinase inhibitor
The following are considered risk factors for the development of focal segmental glomerulosclerosis (FSGS):[3]
- Male gender
- Black race
- Family history
- Heroin abuse
- Drugs known to be associated with FSGS
- Chronic viral infection
- Single kidney status
- Obesity
Less common risk factors
Below conditions and toxins can be a risk factor for nephrotic syndrome[4]
- Adaptation to nephron reduction
- Amyloidosis
- Bee sting
- Castleman's disease
- Chronic interstitial nephritis
- Dermatomyositis
- Diabetes mellitus
- Endocarditis
- Fabry's disease
- Food allergens
- Gold
- Goodpasture's syndrome
- Graft vs. host disease
- Henoch-Schonlein purpura
- Heroin
- HIV
- Infectious mononucleosis
- Interferon
- Kimura's disease
- Leukemia
- Lipoatrophy
- Lithium
- Lymphomas
- Malaria
- Mercury
- Mixed connective tissue disease
- Multiple myeloma
- NSAID
- Obesity
- Oligomeganephronia
- Orthostatic proteinuria
- Penicillamine
- Polyarteritis nodosa
- Pre-eclampsia
- Probenecid
- Renal vein thrombosis
- Rheumatoid arthritis
- Sarcoidosis
- Sickle cell anemia
- Sjogren's syndrome
- Sorafenib
- Streptococcal Infection
- Syphillis
- Systemic lupus erythematosus
- Thyroid disease
- Toxoplasmosis
- Vasculitis
- Viral hepatitis
Drug Induced
- Agalsidase beta
- Certolizumab pegol
- coagulation factor IX
- Olsalazine
- Sodium aurothiomalate
- Trimethadione
- Ziv-aflibercept
References
- ↑ Iijima, Kazumoto; Hamahira, Kiyoshi; Tanaka, Ryojiro; Kobayashi, Akiko; Nozu, Kandai; Nakamura, Hajime; Yoshikawa, Norishige (2002). "Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome". Kidney International. 61 (5): 1801–1805. doi:10.1046/j.1523-1755.2002.00303.x. ISSN 0085-2538.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
- ↑ Sohal, DS; Prabhakar, SS (November 02, 2011). "Focal segmental glomerulosclerosis" (PDF). Interchopen. InTech. Retrieved 3 December 2013. Check date values in:
|date=(help) - ↑ Eddy AA, Symons JM (2003). "Nephrotic syndrome in childhood". Lancet. 362 (9384): 629–39. doi:10.1016/S0140-6736(03)14184-0. PMID 12944064.