Mucormycosis history and symptoms

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Mucormycosis Microchapters


Patient Information


Historical Perspective




Differentiating Mucormycosis from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

X Ray



Other Imaging Findings

Other Diagnostic Studies


Medical Therapy


Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]


Signs and symptoms of mucormycosis differ according to the organ system involvement. Severe infection of the facial sinuses, which may extend into the brain, is the most common presentation leading to proptosis, redness of skin above sinuses, mental status changes, dark scabbing in nasal cavities, fever and headache. Pulmonary mucormycosis may lead to development of cough, hemoptysis with or without chest pain and fever. Gastrointestinal mucormycosis presents as abdominal pain, hematemesis, diarrhea or constipation.


Obtaining history is an important factor in making a diagnosis of mucormycosis since the signs and symptoms may be non-specific and mimic other conditions with similar presentations. Most mucormycosis infections are life-threatening, and develop in the presence of other risk factors such as diabetic ketoacidosis and neutropenia. Severe infection of the facial sinuses, which may extend into the brain, is the most common presentation. Pulmonary, cutaneous, and gastrointestinal (GI) infections are also recognized.

Common Symptoms

Symptoms of rhinocerebral mucormycosis include:

Symptoms of lung (pulmonary) mucormycosis include:

Symptoms of gastrointestinal mucormycosis include:

Symptoms of kidney (renal) mucormycosis include:

Symptoms of skin (cutaneous) mucormycosis include:

  • A single, painful, hardened area of skin that may have a blackened center.

Less Common Symptoms

Mucormycosis may present with atypical features and patient may have atypical signs and symptoms which include the following: