Somatostatin receptor 3: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
Shekel '''Somatostatin receptor type 3''' is a [[protein]] that in humans is encoded by the ''SSTR3'' [[gene]].<ref name="pmid8449518">{{cite journal | vauthors = Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI | title = Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms | journal = Genomics | volume = 15 | issue = 2 | pages = 449–52 | date = February 1993 | pmid = 8449518 | pmc =  | doi = 10.1006/geno.1993.1088 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SSTR3 somatostatin receptor 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6753| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Somatostatin receptor 3
| HGNCid = 11332
| Symbol = SSTR3
| AltSymbols =;
| OMIM = 182453
| ECnumber = 
| Homologene = 20285
| MGIid = 98329
| GeneAtlas_image1 = PBB_GE_SSTR3_214491_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004994 |text = somatostatin receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007187 |text = G-protein signaling, coupled to cyclic nucleotide second messenger}} {{GNF_GO|id=GO:0007267 |text = cell-cell signaling}} {{GNF_GO|id=GO:0008285 |text = negative regulation of cell proliferation}} {{GNF_GO|id=GO:0008628 |text = induction of apoptosis by hormones}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6753
    | Hs_Ensembl = ENSG00000183473
    | Hs_RefseqProtein = NP_001042
    | Hs_RefseqmRNA = NM_001051
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 22
    | Hs_GenLoc_start = 35932191
    | Hs_GenLoc_end = 35938299
    | Hs_Uniprot = P32745
    | Mm_EntrezGene = 20607
    | Mm_Ensembl = ENSMUSG00000044933
    | Mm_RefseqmRNA = NM_009218
    | Mm_RefseqProtein = NP_033244
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 15
    | Mm_GenLoc_start = 78364270
    | Mm_GenLoc_end = 78371600
    | Mm_Uniprot = Q0VB04
  }}
}}
'''Somatostatin receptor 3''', also known as '''SSTR3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SSTR3 somatostatin receptor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6753| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.  The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.  SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets.  SSTR3 is functionally coupled to adenylyl cyclase.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.  The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.  SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets.  SSTR3 is functionally coupled to adenylyl cyclase.<ref name="entrez">{{cite web | title = Entrez Gene: SSTR3 somatostatin receptor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6753| accessdate = }}</ref>
}}


==See also==
== See also ==
* [[Somatostatin receptor]]
* [[Somatostatin receptor]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin|35em}}
{{PBB_Further_reading
* {{cite journal | vauthors = Yamada Y, Reisine T, Law SF, Ihara Y, Kubota A, Kagimoto S, Seino M, Seino Y, Bell GI, Seino S | title = Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase | journal = Molecular Endocrinology | volume = 6 | issue = 12 | pages = 2136–42 | date = December 1992 | pmid = 1337145 | doi = 10.1210/me.6.12.2136 }}
| citations =
* {{cite journal | vauthors = Yamada Y, Post SR, Wang K, Tager HS, Bell GI, Seino S | title = Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 89 | issue = 1 | pages = 251–5 | date = January 1992 | pmid = 1346068 | pmc = 48214 | doi = 10.1073/pnas.89.1.251 }}
*{{cite journal | author=Yamada Y, Reisine T, Law SF, ''et al.'' |title=Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase. |journal=Mol. Endocrinol. |volume=6 |issue= 12 |pages= 2136-42 |year= 1993 |pmid= 1337145 |doi= }}
* {{cite journal | vauthors = Corness JD, Demchyshyn LL, Seeman P, Van Tol HH, Srikant CB, Kent G, Patel YC, Niznik HB | title = A human somatostatin receptor (SSTR3), located on chromosome 22, displays preferential affinity for somatostatin-14 like peptides | journal = FEBS Letters | volume = 321 | issue = 2-3 | pages = 279–84 | date = April 1993 | pmid = 8097479 | doi = 10.1016/0014-5793(93)80124-D }}
*{{cite journal | author=Yamada Y, Post SR, Wang K, ''et al.'' |title=Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 1 |pages= 251-5 |year= 1992 |pmid= 1346068 |doi= }}
* {{cite journal | vauthors = Law SF, Zaina S, Sweet R, Yasuda K, Bell GI, Stadel J, Reisine T | title = Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation | journal = Molecular Pharmacology | volume = 45 | issue = 4 | pages = 587–90 | date = April 1994 | pmid = 8183236 | doi =  }}
*{{cite journal | author=Corness JD, Demchyshyn LL, Seeman P, ''et al.'' |title=A human somatostatin receptor (SSTR3), located on chromosome 22, displays preferential affinity for somatostatin-14 like peptides. |journal=FEBS Lett. |volume=321 |issue= 2-3 |pages= 279-84 |year= 1993 |pmid= 8097479 |doi= }}
* {{cite journal | vauthors = Kaupmann K, Bruns C, Hoyer D, Seuwen K, Lübbert H | title = Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain | journal = FEBS Letters | volume = 331 | issue = 1-2 | pages = 53–9 | date = September 1993 | pmid = 8405411 | doi = 10.1016/0014-5793(93)80296-7 }}
*{{cite journal | author=Law SF, Zaina S, Sweet R, ''et al.'' |title=Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation. |journal=Mol. Pharmacol. |volume=45 |issue= 4 |pages= 587-90 |year= 1994 |pmid= 8183236 |doi=  }}
* {{cite journal | vauthors = Sharma K, Patel YC, Srikant CB | title = Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3 | journal = Molecular Endocrinology | volume = 10 | issue = 12 | pages = 1688–96 | date = December 1996 | pmid = 8961277 | doi = 10.1210/me.10.12.1688 }}
*{{cite journal | author=Kaupmann K, Bruns C, Hoyer D, ''et al.'' |title=Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. |journal=FEBS Lett. |volume=331 |issue= 1-2 |pages= 53-9 |year= 1993 |pmid= 8405411 |doi= }}
* {{cite journal | vauthors = Fukusumi S, Kitada C, Takekawa S, Kizawa H, Sakamoto J, Miyamoto M, Hinuma S, Kitano K, Fujino M | title = Identification and characterization of a novel human cortistatin-like peptide | journal = Biochemical and Biophysical Research Communications | volume = 232 | issue = 1 | pages = 157–63 | date = March 1997 | pmid = 9125122 | doi = 10.1006/bbrc.1997.6252 }}
*{{cite journal | author=Yamada Y, Stoffel M, Espinosa R, ''et al.'' |title=Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. |journal=Genomics |volume=15 |issue= 2 |pages= 449-52 |year= 1993 |pmid= 8449518 |doi= 10.1006/geno.1993.1088 }}
* {{cite journal | vauthors = Ain KB, Taylor KD, Tofiq S, Venkataraman G | title = Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 82 | issue = 6 | pages = 1857–62 | date = June 1997 | pmid = 9177396 | doi = 10.1210/jc.82.6.1857 }}
*{{cite journal | author=Sharma K, Patel YC, Srikant CB |title=Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3. |journal=Mol. Endocrinol. |volume=10 |issue= 12 |pages= 1688-96 |year= 1997 |pmid= 8961277 |doi= }}
* {{cite journal | vauthors = de Lecea L, Ruiz-Lozano P, Danielson PE, Peelle-Kirley J, Foye PE, Frankel WN, Sutcliffe JG | title = Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin | journal = Genomics | volume = 42 | issue = 3 | pages = 499–506 | date = June 1997 | pmid = 9205124 | doi = 10.1006/geno.1997.4763 }}
*{{cite journal | author=Fukusumi S, Kitada C, Takekawa S, ''et al.'' |title=Identification and characterization of a novel human cortistatin-like peptide. |journal=Biochem. Biophys. Res. Commun. |volume=232 |issue= 1 |pages= 157-63 |year= 1997 |pmid= 9125122 |doi= 10.1006/bbrc.1997.6252 }}
* {{cite journal | vauthors = Roth A, Kreienkamp HJ, Meyerhof W, Richter D | title = Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and internalization | journal = The Journal of Biological Chemistry | volume = 272 | issue = 38 | pages = 23769–74 | date = September 1997 | pmid = 9295322 | doi = 10.1074/jbc.272.38.23769 }}
*{{cite journal | author=Ain KB, Taylor KD, Tofiq S, Venkataraman G |title=Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. |journal=J. Clin. Endocrinol. Metab. |volume=82 |issue= 6 |pages= 1857-62 |year= 1997 |pmid= 9177396 |doi= }}
* {{cite journal | vauthors = Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP | title = The DNA sequence of human chromosome 22 | journal = Nature | volume = 402 | issue = 6761 | pages = 489–95 | date = December 1999 | pmid = 10591208 | doi = 10.1038/990031 }}
*{{cite journal | author=de Lecea L, Ruiz-Lozano P, Danielson PE, ''et al.'' |title=Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. |journal=Genomics |volume=42 |issue= 3 |pages= 499-506 |year= 1997 |pmid= 9205124 |doi= 10.1006/geno.1997.4763 }}
* {{cite journal | vauthors = Zatelli MC, Tagliati F, Taylor JE, Rossi R, Culler MD, degli Uberti EC | title = Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 86 | issue = 5 | pages = 2161–9 | date = May 2001 | pmid = 11344221 | doi = 10.1210/jc.86.5.2161 }}
*{{cite journal | author=Roth A, Kreienkamp HJ, Meyerhof W, Richter D |title=Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and internalization. |journal=J. Biol. Chem. |volume=272 |issue= 38 |pages= 23769-74 |year= 1997 |pmid= 9295322 |doi= }}
* {{cite journal | vauthors = Talme T, Ivanoff J, Hägglund M, Van Neerven RJ, Ivanoff A, Sundqvist KG | title = Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3 | journal = Clinical and Experimental Immunology | volume = 125 | issue = 1 | pages = 71–9 | date = July 2001 | pmid = 11472428 | pmc = 1906108 | doi = 10.1046/j.1365-2249.2001.01577.x }}
*{{cite journal | author=Dunham I, Shimizu N, Roe BA, ''et al.'' |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489-95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 }}
* {{cite journal | vauthors = Pasquali D, Notaro A, Esposito D, Vassallo P, Bonavolontà G, Bellastella A, Sinisi AA | title = [Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy] | journal = Minerva Endocrinologica | volume = 26 | issue = 3 | pages = 175–9 | date = September 2001 | pmid = 11753241 | doi =  }}
*{{cite journal | author=Zatelli MC, Tagliati F, Taylor JE, ''et al.'' |title=Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 5 |pages= 2161-9 |year= 2001 |pmid= 11344221 |doi= }}
* {{cite journal | vauthors = Papotti M, Bongiovanni M, Volante M, Allìa E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G | title = Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis | journal = Virchows Archiv | volume = 440 | issue = 5 | pages = 461–75 | date = May 2002 | pmid = 12021920 | doi = 10.1007/s00428-002-0609-x }}
*{{cite journal | author=Talme T, Ivanoff J, Hägglund M, ''et al.'' |title=Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3. |journal=Clin. Exp. Immunol. |volume=125 |issue= 1 |pages= 71-9 |year= 2001 |pmid= 11472428 |doi=  }}
* {{cite journal | vauthors = Ferone D, Pivonello R, Van Hagen PM, Dalm VA, Lichtenauer-Kaligis EG, Waaijers M, Van Koetsveld PM, Mooy DM, Colao A, Minuto F, Lamberts SW, Hofland LJ | title = Quantitative and functional expression of somatostatin receptor subtypes in human thymocytes | journal = American Journal of Physiology. Endocrinology and Metabolism | volume = 283 | issue = 5 | pages = E1056-66 | date = November 2002 | pmid = 12376335 | doi = 10.1152/ajpendo.00205.2001 }}
*{{cite journal | author=Pasquali D, Notaro A, Esposito D, ''et al.'' |title=[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy] |journal=Minerva Endocrinol. |volume=26 |issue= 3 |pages= 175-9 |year= 2002 |pmid= 11753241 |doi= }}
* {{cite journal | vauthors = Pasquali D, Notaro A, Bonavolonta' G, Vassallo P, Bellastella A, Sinisi AA | title = Somatostatin receptor genes are expressed in lymphocytes from retroorbital tissues in Graves' disease | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 87 | issue = 11 | pages = 5125–9 | date = November 2002 | pmid = 12414882 | doi = 10.1210/jc.2002-020790 }}
*{{cite journal | author=Papotti M, Bongiovanni M, Volante M, ''et al.'' |title=Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis. |journal=Virchows Arch. |volume=440 |issue= 5 |pages= 461-75 |year= 2002 |pmid= 12021920 |doi= 10.1007/s00428-002-0609-x }}
* {{cite journal | vauthors = Dizeyi N, Konrad L, Bjartell A, Wu H, Gadaleanu V, Hansson J, Helboe L, Abrahamsson PA | title = Localization and mRNA expression of somatostatin receptor subtypes in human prostatic tissue and prostate cancer cell lines | journal = Urologic Oncology | volume = 7 | issue = 3 | pages = 91–8 | year = 2002 | pmid = 12474541 | doi = 10.1016/S1078-1439(01)00173-9 }}
*{{cite journal | author=Ferone D, Pivonello R, Van Hagen PM, ''et al.'' |title=Quantitative and functional expression of somatostatin receptor subtypes in human thymocytes. |journal=Am. J. Physiol. Endocrinol. Metab. |volume=283 |issue= 5 |pages= E1056-66 |year= 2002 |pmid= 12376335 |doi= 10.1152/ajpendo.00205.2001 }}
*{{cite journal | author=Pasquali D, Notaro A, Bonavolonta' G, ''et al.'' |title=Somatostatin receptor genes are expressed in lymphocytes from retroorbital tissues in Graves' disease. |journal=J. Clin. Endocrinol. Metab. |volume=87 |issue= 11 |pages= 5125-9 |year= 2002 |pmid= 12414882 |doi= }}
*{{cite journal  | author=Dizeyi N, Konrad L, Bjartell A, ''et al.'' |title=Localization and mRNA expression of somatostatin receptor subtypes in human prostatic tissue and prostate cancer cell lines. |journal=Urol. Oncol. |volume=7 |issue= 3 |pages= 91-8 |year= 2002 |pmid= 12474541 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
}}
{{refend}}
{{refend}}


==External links==
== External links ==
* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1298 IUPHAR Receptor Database - Somatostatin Receptors]
* {{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2437 | title = Somatostatin Receptors: sst<sub>3</sub> | accessdate = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | archiveurl = | archivedate = | quote = }}
* {{MeshName|somatostatin+receptor+3}}
* {{MeshName|somatostatin+receptor+3}}


{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
{{membrane-protein-stub}}
{{GH/IGF-1 axis signaling modulators}}
{{NLM content}}
{{NLM content}}
[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}

Revision as of 00:57, 27 October 2017

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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene.[1][2]

Function

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.[2]

See also

References

  1. ↑ Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
  2. ↑ 2.0 2.1 "Entrez Gene: SSTR3 somatostatin receptor 3".

Further reading

  • Yamada Y, Reisine T, Law SF, Ihara Y, Kubota A, Kagimoto S, Seino M, Seino Y, Bell GI, Seino S (December 1992). "Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase". Molecular Endocrinology. 6 (12): 2136–42. doi:10.1210/me.6.12.2136. PMID 1337145.
  • Yamada Y, Post SR, Wang K, Tager HS, Bell GI, Seino S (January 1992). "Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney". Proceedings of the National Academy of Sciences of the United States of America. 89 (1): 251–5. doi:10.1073/pnas.89.1.251. PMC 48214. PMID 1346068.
  • Corness JD, Demchyshyn LL, Seeman P, Van Tol HH, Srikant CB, Kent G, Patel YC, Niznik HB (April 1993). "A human somatostatin receptor (SSTR3), located on chromosome 22, displays preferential affinity for somatostatin-14 like peptides". FEBS Letters. 321 (2–3): 279–84. doi:10.1016/0014-5793(93)80124-D. PMID 8097479.
  • Law SF, Zaina S, Sweet R, Yasuda K, Bell GI, Stadel J, Reisine T (April 1994). "Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation". Molecular Pharmacology. 45 (4): 587–90. PMID 8183236.
  • Kaupmann K, Bruns C, Hoyer D, Seuwen K, Lübbert H (September 1993). "Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain". FEBS Letters. 331 (1–2): 53–9. doi:10.1016/0014-5793(93)80296-7. PMID 8405411.
  • Sharma K, Patel YC, Srikant CB (December 1996). "Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3". Molecular Endocrinology. 10 (12): 1688–96. doi:10.1210/me.10.12.1688. PMID 8961277.
  • Fukusumi S, Kitada C, Takekawa S, Kizawa H, Sakamoto J, Miyamoto M, Hinuma S, Kitano K, Fujino M (March 1997). "Identification and characterization of a novel human cortistatin-like peptide". Biochemical and Biophysical Research Communications. 232 (1): 157–63. doi:10.1006/bbrc.1997.6252. PMID 9125122.
  • Ain KB, Taylor KD, Tofiq S, Venkataraman G (June 1997). "Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines". The Journal of Clinical Endocrinology and Metabolism. 82 (6): 1857–62. doi:10.1210/jc.82.6.1857. PMID 9177396.
  • de Lecea L, Ruiz-Lozano P, Danielson PE, Peelle-Kirley J, Foye PE, Frankel WN, Sutcliffe JG (June 1997). "Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin". Genomics. 42 (3): 499–506. doi:10.1006/geno.1997.4763. PMID 9205124.
  • Roth A, Kreienkamp HJ, Meyerhof W, Richter D (September 1997). "Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and internalization". The Journal of Biological Chemistry. 272 (38): 23769–74. doi:10.1074/jbc.272.38.23769. PMID 9295322.
  • Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (December 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
  • Zatelli MC, Tagliati F, Taylor JE, Rossi R, Culler MD, degli Uberti EC (May 2001). "Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt". The Journal of Clinical Endocrinology and Metabolism. 86 (5): 2161–9. doi:10.1210/jc.86.5.2161. PMID 11344221.
  • Talme T, Ivanoff J, Hägglund M, Van Neerven RJ, Ivanoff A, Sundqvist KG (July 2001). "Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3". Clinical and Experimental Immunology. 125 (1): 71–9. doi:10.1046/j.1365-2249.2001.01577.x. PMC 1906108. PMID 11472428.
  • Pasquali D, Notaro A, Esposito D, Vassallo P, Bonavolontà G, Bellastella A, Sinisi AA (September 2001). "[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy]". Minerva Endocrinologica. 26 (3): 175–9. PMID 11753241.
  • Papotti M, Bongiovanni M, Volante M, Allìa E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G (May 2002). "Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75. doi:10.1007/s00428-002-0609-x. PMID 12021920.
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