5-HT1F receptor

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The correct title of this article is 5-HT1F receptor. It appears incorrectly here because of technical restrictions.

5-hydroxytryptamine (serotonin) receptor 1F
Symbol(s) HTR1F; 5-HT1F; HTR1EL; MR77
External IDs OMIM: 182134 MGI99842 Homologene37361
RNA expression pattern

PBB GE HTR1F 221458 at tn.png

More reference expression data

Human Mouse
Entrez 3355 15557
Ensembl ENSG00000179097 ENSMUSG00000050783
Uniprot P30939 Q543V2
Refseq NM_000866 (mRNA)
NP_000857 (protein)
NM_008310 (mRNA)
NP_032336 (protein)
Location Chr 3: 88.12 - 88.12 Mb Chr 16: 64.87 - 65.05 Mb
Pubmed search [1] [2]

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.[1]


See also


  1. "Entrez Gene: HTR1F 5-hydroxytryptamine (serotonin) receptor 1F". 
  2. Wainscott DB, Krushinski JH, Audia JE, Schaus JM, Zgombick JM, Lucaites VL, Nelson DL (2005). "[3H]-LY-334,370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties". Naunyn Schmiedebergs Arch. Pharmacol. 371 (3): 169–77. PMID 15900510. doi:10.1007/s00210-005-1035-9. 
  3. Zhang D, Kohlman D, Krushinski J, Liang S, Ying BP, Reilly JE, Dinn SR, Wainscott DB, Nutter S, Gough W, Nelson DL, Schaus JM, Xu YC (2004). "Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists". Bioorg. Med. Chem. Lett. 14 (24): 6011–6. PMID 15546719. doi:10.1016/j.bmcl.2004.09.079. 

Further reading

  • Hoyer D, Hannon JP, Martin GR (2002). "Molecular, pharmacological and functional diversity of 5-HT receptors.". Pharmacol. Biochem. Behav. 71 (4): 533–54. PMID 11888546. 
  • Raymond JR, Mukhin YV, Gelasco A; et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction.". Pharmacol. Ther. 92 (2-3): 179–212. PMID 11916537. 
  • Amlaiky N, Ramboz S, Boschert U; et al. (1992). "Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus.". J. Biol. Chem. 267 (28): 19761–4. PMID 1328180. 
  • Adham N, Kao HT, Schecter LE; et al. (1993). "Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.". Proc. Natl. Acad. Sci. U.S.A. 90 (2): 408–12. PMID 8380639. 
  • Lovenberg TW, Erlander MG, Baron BM; et al. (1993). "Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes.". Proc. Natl. Acad. Sci. U.S.A. 90 (6): 2184–8. PMID 8384716. 
  • Maassen VanDenBrink A, Vergouwe MN, Ophoff RA; et al. (1999). "Chromosomal localization of the 5-HT1F receptor gene: no evidence for involvement in response to sumatriptan in migraine patients.". Am. J. Med. Genet. 77 (5): 415–20. PMID 9632173. 
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932. doi:10.1073/pnas.242603899. 
  • Bhatnagar A, Sheffler DJ, Kroeze WK; et al. (2004). "Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors.". J. Biol. Chem. 279 (33): 34614–23. PMID 15190056. doi:10.1074/jbc.M404673200. 
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMID 15489334. doi:10.1101/gr.2596504. 
  • Hannula-Jouppi K, Kaminen-Ahola N, Taipale M; et al. (2006). "The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia.". PLoS Genet. 1 (4): e50. PMID 16254601. doi:10.1371/journal.pgen.0010050. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub