Ketotifen
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| Image:Ketotifen structure.svg | |
| Ketotifen
| |
| Systematic (IUPAC) name | |
| 4,9-dihydro-4-(1-methyl-4-piperidinylidene)- 10H-benzocyclohepta[1,2-b]thiopen-10-one | |
| Identifiers | |
| CAS number | |
| ATC code | R06 S01GX08 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C19H19NOS |
| Mol. mass | 309.426 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 60% |
| Protein binding | 75% |
| Metabolism | Hepatic |
| Half life | 21 Hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral, Eye Drops |
Ketotifen fumarate (ophthalmic solutions marketed under the brand name Zaditor (Novartis) and Alaway (Bausch and Lomb)) is an H1-antihistamine/mast cell stabilizer available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds.
General Information
Ketotifen relieves and prevents eye itchiness and/or irritation associated with most seasonal allergies. It starts working within minutes after administering the drops. The drug has not been studied in children under 3.
Overdosage
Accidental ingestion of an entire bottle of ketotifen is unlikely to cause side effects since it contains less than 2 mg of medicine.
External links
- Zaditor web site
- {http://www.bausch.com/en_US/consumer/visioncare/product/drops/alaway_con.aspx Alaway web site]
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
