Gynecomastia natural history, complications and prognosis: Difference between revisions

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===Natural History===
===Natural History===
* The signs of gynecomastia usually develops in neonatal, in pubertal age or in elderly.
* The signs of gynecomastia usually develops in neonatal, in pubertal age or in elderly.<ref name="pmid8421478">{{cite journal| author=Braunstein GD| title=Gynecomastia. | journal=N Engl J Med | year= 1993 | volume= 328 | issue= 7 | pages= 490-5 | pmid=8421478 | doi=10.1056/NEJM199302183280708 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8421478  }} </ref>
 
* Without treatment gynecomastia has some associated risk of breast cancer, however, the majority of physiological gynecomastia resolves in months to years time.
* Without treatment gynecomastia has some associated risk of breast cancer, however, the majority of physiological gynecomastia resolves in months to years time.
* Secondary gynecomastia usually responds to treatment or removal of the underlying cause.
* Secondary gynecomastia usually responds to treatment or removal of the underlying cause.



Revision as of 20:02, 8 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

  • If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
  • Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

  • The signs of gynecomastia usually develops in neonatal, in pubertal age or in elderly.[1]
  • Without treatment gynecomastia has some associated risk of breast cancer, however, the majority of physiological gynecomastia resolves in months to years time.
  • Secondary gynecomastia usually responds to treatment or removal of the underlying cause.

Complications

  • Complications of gynecomastia include:
    • Persistent pubertal gynecomastia
    • Breast cancer[2]
    • Psychological stressess[3] [4]

Prognosis

  • Gynecomastia is a benign breast enlargement and the majority of adolescent gynecomastia resolved spontaneously.
  • Persistent gynecomastia can cause psychosocial stresses and can be treated with surgical options with a good outcome.[5] [6] [7]

References

  1. Braunstein GD (1993). "Gynecomastia". N Engl J Med. 328 (7): 490–5. doi:10.1056/NEJM199302183280708. PMID 8421478.
  2. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID org/10.1016/j.amjmed.2016.01.009 Check |pmid= value (help).
  3. Ordaz DL, Thompson JK (2015). "Gynecomastia and psychological functioning: A review of the literature". Body Image. 15: 141–8. doi:10.1016/j.bodyim.2015.08.004. PMID 26408934.
  4. Rew L, Young C, Harrison T, Caridi R (2015). "A systematic review of literature on psychosocial aspects of gynecomastia in adolescents and young men". J Adolesc. 43: 206–12. doi:10.1016/j.adolescence.2015.06.007. PMID 26151806.
  5. Wiesman, IM.; et al. "Gynecomastia: An Outcome Analysis".
  6. Li CC, Fu JP, Chang SC, Chen TM, Chen SG (2012). "Surgical treatment of gynecomastia: complications and outcomes". Ann Plast Surg. 69 (5): 510–5. doi:10.1097/SAP.0b013e318222834d. PMID 21712702.
  7. Choi BS, Lee SR, Byun GY, Hwang SB, Koo BH (2017). "The Characteristics and Short-Term Surgical Outcomes of Adolescent Gynecomastia". Aesthetic Plast Surg. doi:10.1007/s00266-017-0886-z. PMID 28451801.

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