Sandbox: malabsorption: Difference between revisions

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! colspan="2" style="background:#DCDCDC;" align="center" |[[Carcinoid syndrome|Carcinoid tumor]]
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* [[Lymphadenopathy|Cervical lymphadenopathy]]
** [[Tachycardia]]
*** [[Hypertension]]
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Revision as of 16:38, 15 December 2017

Diarrhea

Abbreviations: GI: Gastrointestinal, CBC: Complete blood count, WBC: White blood cell, RBC: Red blood cell, Plt: Platelet, Hgb: Hemoglobin, ESR: Erythrocyte sedimentation rate, CRP: C–reactive protein, IgE: Immunoglobulin E, IgA: Immunoglobulin A, ETEC: Escherichia coli enteritis, EPEC: Enteropathogenic Escherichia coli, EIEC: Enteroinvasive Escherichia coli, EHEC: Enterohemorrhagic Escherichia coli, EAEC: Enteroaggregative Escherichia coli,

Categories Cause Clinical manifestation Lab findings Extra intestinal findings Cause/Pathogenesis Gold standard diagnosis
Symptoms GI signs
Duration Diarrhea Fever Abdominal pain Weight loss
Stool exam CBC Other lab findings
Acute Chronic Watery Bloody Fatty WBC RBC Ova/Parasite Osmotic gap Other WBC Hgb Plt
Gastrointestinal Crohns disease + + + + ± + + + +
  • Abnormal immune response to self antigens
Ulcerative colitis + + + + + + + + +
  • Abnormal immune response to self antigens
Celiac disease + ± ± + +
Cystic fibrosis + + ± + +
Chronic pancreatitis + + + + +
Bile acid malabsorption + + + +
Microscopic colitis + + + +
Infective colitis + + + + + + + + +
Ischemic colitis + + + + + + + + +
Lactose intolerance + + + +
Irritable bowel syndrome + ± ± ±
  • Diagnosis of exclusion
Infection Bacterial Whipple's disease + + + ± + + ↓/↑
Tropical sprue + + + + + + + +
  • Diagnosis of exclusion
Small bowel bacterial overgrowth + + + + + +
  • Diagnosis of exclusion
Pseudomembranous enterocolitis + + ± + + ± + +
Shigellosis + + + + + + + ↑/↓
Salmonellosis + + + + + + + +
 Campylobacteriosis + + + + + + +
Escherichia coli enteritis ETEC

(Traveler's diarrhea)

+ + + +
EPEC + + + + + + + + +
EIEC + + + + + + +
EHEC + + + +
EAEC + + + +
Yersinia enterocolitica + + + + +
Vibrio cholera + + +
Aeromonas +
Plesiomonas +
Mycobacterium avium complex + + + +/– +
+/– +
  • Immune system analysis may show defects
Other infections
  • aaaa
  • bbbb
+ + + +/–
+ +
  • Stool culture may be positive for responsible organism
Virus Rotavirus + + +
Echovirus
Adenovirus + + +
Norovirus + + + +
CMV colitis + + + +/– +
+/– +
  • CD 4 level decreased as it is maily associated with HIV
HIV + +
Hepatitis Hepatitis A +
Hepatitis E +
Parasite Entamoeba histolytica + + +
+
Giardia
+
Cryptosporidium
+
Microsporidia
+
Isospora + + +
+ + +
Other Parasitic diarrhea
  • aaaa
  • bbbb
+ + + + +/–
+ + +
Tumors Carcinoid tumor + + + - - + +
VIPoma + + + + + +
  • Primary secretory tumor
  • Elevated VIP levels
  • Followed by imaging
Zollinger–Ellison syndrome + + + + +
  • Elevated basal or stimulated serum gastrin> 120 pg/mL
Somatostatinoma
Lymphoma
Colorectal cancer + + + + + + +
Medication/Toxicity Drug induced enteritis
Laxative abuse
Heavy metal ingestion
Organophosphate poisoning
Opium withdrawal
Iatrogenic Short bowel syndrome + + + + +
  • Surgical intestinal resection
Radiation enteritis
Dumping syndrome + + + +
Others Abetalipoproteinemia + + + + +
Hyperthyroidism + + ± + +
  • Elevated T4
  • Elevated T3
  • Decreased TSH
Diabetic neuropathy
Systemic sclerosis + + + + +
+