Iritis

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Iritis
Iritis.jpg
A case of Iritis of the right eye

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Iritis is a form of anterior uveitis and refers to the inflammation of the iris of the eye.

Types

There are two main types of iritis: acute and chronic. Acute iritis is a type of iritis that can heal independently within a few weeks. If treatment is provided, acute iritis improves quickly. Chronic iritis can exist for months or years before recovery occurs. Chronic iritis does not respond to treatment as well as acute iritis does. Chronic iritis is also accompanied by a higher risk of serious visual impairment.

Signs and symptoms

  • Ocular and periorbital pain
  • Photophobia
  • Consensual photophobia (pain in affected eye when light is shone in unaffected eye)
  • Blurred or cloudy vision
  • Reddened eye, especially adjacent to the iris
  • White blood cells (leukocytes) (resulting in a grey or near-white haze) and protein (resulting in tiny white dots) in the anterior chamber, often called "cells and flare."
  • Synechia or adhesion of iris to lens or cornea

Causes

Life Threatening Causes

Common Causes

Causes by Organ System

Cardiovascular Autoimmune retinal vasculitis, Ocular ischemic syndrome
Chemical/Poisoning Box jellyfish poisoning 
Dental No underlying causes
Dermatologic Behçet's disease, Chronic psoriasis, Dermatostomatitis, Lepromatous leprosy, Psoriatic arthritis, Stevens-johnson syndrome
Drug Side Effect Etidronate, Fomivirsen sodium, Meclofenamate, Medrysone, Pembrolizumab, Rifabutin, Tetracaine, Trametinib, Vemurafenib
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental Foreign body
Gastroenterologic Crohn's disease, Inflammatory bowel disease, Ulcerative colitis, Ulcerative proctosigmoiditis 
Genetic Alezzandrini syndrome, Blau syndrome, Hla-b27 disorder, Phosgene oxime
Hematologic Granulomatosis with polyangiitis, Wegener's granulomatosis
Iatrogenic No underlying causes
Infectious Disease Cat scratch fever, Dabrafenib, Euphorbiaceae , Herpes simplex, Herpes zoster, Htlv-1, Lepromatous leprosy, Leptospirosis, Lyme disease, Malaria, Mycobacterium tuberculosis, Onchocerciasis, Secondary syphilis, Syphilis, Toxocariasis, Toxoplasmosis, Tuberculosis, Ulcerative proctosigmoiditis , Weil's syndrome
Musculoskeletal/Orthopedic Ankylosing spondylitis, Connective tissue diseases, Polychondritis
Neurologic Charlin's syndrome, Heerfordt-waldenstroem syndrome, Multiple sclerosis
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic Autoimmune retinal vasculitis, Birdshot retinochoroidopathy, Charlin's syndrome, Fuchs' heterochromic cyclitis, Incontinentia pigmenti, Ocular ischemic syndrome, Pars planitis, Sympathetic ophthalmitis, Vogt-koyanagi-harada syndrome
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Sarcoidosis, Tuberculosis
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy Ankylosing spondylitis, Behçet's disease, Birdshot retinochoroidopathy, Blau syndrome, Chronic psoriasis, Granulomatosis with polyangiitis, Heerfordt-waldenstroem syndrome, Juvenile chronic arthritis, Juvenile rheumatoid arthritis , Psoriatic arthritis, Reactive arthritis, Reiter's disease, Rheumatoid arthritis, Rheumatoid disease, Sarcoidosis, Scleroderma, Still's disease, Systemic lupus erythematosus, Vogt-koyanagi-harada syndrome, Wegener's granulomatosis
Sexual Secondary syphilis, Syphilis
Trauma Blunt trauma
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

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Complications

Complications of iritis may include the following: Cataract, glaucoma, corneal calcification, posterior uveitis, blindness, band keratopathy, and cystoid macular oedema.


Treatment

External links

de:Iritis it:Irite fi:Värikalvontulehdus


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