P2RX2

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Identifiers
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External IDsGeneCards: [1]
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SpeciesHumanMouse
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P2X purinoceptor 2 is a protein that in humans is encoded by the P2RX2 gene.[1][2][3]

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.[3]

See also

References

  1. Lynch KJ, Touma E, Niforatos W, Kage KL, Burgard EC, van Biesen T, Kowaluk EA, Jarvis MF (Dec 1999). "Molecular and functional characterization of human P2X(2) receptors". Mol Pharmacol. 56 (6): 1171–81. PMID 10570044.
  2. Brake AJ, Wagenbach MJ, Julius D (Oct 1994). "New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor". Nature. 371 (6497): 519–23. doi:10.1038/371519a0. PMID 7523952.
  3. 3.0 3.1 "Entrez Gene: P2RX2 purinergic receptor P2X, ligand-gated ion channel, 2".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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