Muscle type nicotinic receptor
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The muscle type nicotinic receptor is a type of nicotinic acetylcholine receptor, consisting of the subunit combination (α1)2β1δε[1].
It is located in the neuromuscular junction, where activation yields EPSP, mainly by increased Na+ and K+ permeability.
Agonists
Nicotinic agonists for this receptor include:
Antagonists
References
- ↑ Pharmacology, (Rang, Dale, Ritter & Moore, ISBN 0443071454, 5:th ed., Churchill Livingstone 2003) Page 138.
- ↑ Neurosci.pharm - MBC 3320 Acetylcholine
Ion channel, receptor: ligand-gated ion channels | |
|---|---|
| Cys-loop receptors | 5-HT receptor (5-HT3 serotonin receptor (A)) - GABA receptor (GABA A (α1, α2, α3, α5, α6, β1, β2, β3, γ2, ε), GABA C (ρ1)) - Glycine receptor (α1) - Nicotinic acetylcholine receptor (α1, α2, α3, α4, α5, α7, β2, β3, β4, δ, ε, (α4)2(β2)3, (α7)5, Ganglion type, Muscle type) |
| Ionotropic glutamate receptors | AMPA (1, 2, 3, 4) - Kainate (1, 2) - NMDA (1, 2A, 2B, 2C, 2D) |
| ATP-gated channels | Purinergic receptors (P2X (1, 4, 5, 7)) |
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