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{{Nephrotic syndrome}}
{{Nephrotic syndrome}}
{{CMG}}; {{AE}} [[User:YazanDaaboul|Yazan Daaboul]], [[User:Sergekorjian|Serge Korjian]]


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==Overview==
The hallmark of nephrotic syndrome is [[edema]]. A positive history of renal disease, systemic diseases such as [[diabetes mellitus]], [[amyloidosis]], or [[systemic lupus erythematosus]], and medication use is suggestive of nephrotic syndrome. The most common symptoms of nephrotic syndrome include volume overload, foamy urine, and [[fatigue]].
==History and Symptoms==
* The hallmark of nephrotic syndrome is [[edema]]. A positive history of renal disease, systemic diseases such as [[diabetes mellitus]], [[amyloidosis]], or [[systemic lupus erythematosus]], and medication use is suggestive of nephrotic syndrome. The most common symptoms of nephrotic syndrome include volume overload, foamy urine, and [[fatigue]].<ref name="Liebeskind2014">{{cite journal|last1=Liebeskind|first1=David S.|title=Nephrotic syndrome|volume=119|year=2014|pages=405–415|issn=00729752|doi=10.1016/B978-0-7020-4086-3.00026-6}}</ref><ref name="SinhaBagga2012">{{cite journal|last1=Sinha|first1=Aditi|last2=Bagga|first2=Arvind|title=Nephrotic Syndrome|journal=The Indian Journal of Pediatrics|volume=79|issue=8|year=2012|pages=1045–1055|issn=0019-5456|doi=10.1007/s12098-012-0776-y}}</ref>


{{CMG}}
=== History ===
==Symptoms==
Patients with nephrotic syndrome may have a positive history of:
Swelling is the most common symptom. It may occur:
* [[Kidney|Renal disease]]
* Systemic disease such as [[diabetes mellitus]], [[amyloidosis]], or [[systemic lupus erythematosus]]
* Medication use


*In the face and around the eyes.
=== Common Symptoms ===
*In the arms and legs, especially in the feet and ankles
Common symptoms of nephrotic syndrome include:
*In the belly area (swollen abdomen)
*Symptoms of [[proteinuria]], such as foamy urine
Other symptoms include:
*Volume overload that manifests as:
*Foamy appearance of the urine
**[[Swelling]] of lower extremities and genitals
*[[Weight gain]] (unintentional) from fluid retention
**[[Abdominal fullness]] suggestive of [[ascites]]
*[[Poor appetite]]
**[[Anasarca]]
**[[Dyspnea]] suggestive of [[pulmonary edema]]
**[[Weight gain]]
 
=== Less Common Symptoms ===
Less common symptoms of nephrotic syndrome include:
* [[Fatigue]]
*[[Anorexia]]
*Symptoms of associated complications
**Symptoms of [[high blood pressure]], such as [[headache]] and [[visual disturbance]]
**Symptoms of [[deep vein thrombosis]]  
**Symptoms of [[Infection|infections]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Kidney diseases]]
 
[[Category:Medicine]]
[[Category:Nephrology]]
[[Category:Nephrology]]
[[Category:Pediatrics]]
[[Category:Up-To-Date]]
[[Category:Disease]]
[[Category:Emergency medicine]]
[[Category:Syndromes]]
[[Category:Needs content]]
[[Category:Needs overview]]
{{WH}}
{{WS}}

Latest revision as of 22:57, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian

Overview

The hallmark of nephrotic syndrome is edema. A positive history of renal disease, systemic diseases such as diabetes mellitus, amyloidosis, or systemic lupus erythematosus, and medication use is suggestive of nephrotic syndrome. The most common symptoms of nephrotic syndrome include volume overload, foamy urine, and fatigue.

History and Symptoms

History

Patients with nephrotic syndrome may have a positive history of:

Common Symptoms

Common symptoms of nephrotic syndrome include:

Less Common Symptoms

Less common symptoms of nephrotic syndrome include:

References

  1. Liebeskind, David S. (2014). "Nephrotic syndrome". 119: 405–415. doi:10.1016/B978-0-7020-4086-3.00026-6. ISSN 0072-9752.
  2. Sinha, Aditi; Bagga, Arvind (2012). "Nephrotic Syndrome". The Indian Journal of Pediatrics. 79 (8): 1045–1055. doi:10.1007/s12098-012-0776-y. ISSN 0019-5456.