Menopause causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Menopause occurs naturally or can be induced, Induced menopause happens as a result of bilateral oophorectomy, hysterectomy, salpingo-oophorectomy, a complication of tubal ligation, complications of treatment, such as chemotherapy and radiotherapy, autoimmune diseases such as thyroid disease, rheumatoid arthritis, Turner’s syndrome, myalgic encephalomyelitis/chronic fatigue syndrome, polycystic ovary syndrome, premature ovarian insufficiency Several risk factors accelerate happen early menopause such as Undiagnosed and untreated coeliac disease, family history and smoking, women who smoke have early menopause before non-smoking women, family history.[1][2]
causes
It is the result of the eventual atresia of almost all oocytes in the ovaries. This causes an increase in circulating follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels as there are a decreased number of oocytes responding to these hormones and producing estrogen. This decrease in the production of estrogen leads to the perimenopausal symptoms of hot flashes, insomnia, and mood changes, as well as post-menopausal osteoporosis and vaginal atrophy.
However, menopause can be surgically induced by bilateral salpingo-oophorectomy (removal of both ovaries and both fallopian tubes), which is often, but not always, done in conjunction with hysterectomy. Cessation of menses as a result of removal of the ovaries is called "surgical menopause". The sudden and complete drop in reproductive hormone levels usually produces extreme hormone-withdrawal symptoms such as hot flashes, etc.
As mentioned above, removal of the uterus, hysterectomy, does not itself cause menopause, although pelvic surgery can sometimes precipitate somewhat earlier menopause, perhaps because of compromised blood supply to the ovaries. Removing the ovaries, however, causes an immediate and powerful "surgical menopause", even if the uterus is left intact.
Cigarette smoking has been found to decrease the age at menopause by as much as one year, and women who have undergone hysterectomy with ovary conservation go through menopause 3.7 years earlier than average. However, premature menopause (before the age of 40) is generally idiopathic.
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