Hypertrophic cardiomyopathy physical examination: Difference between revisions

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==Overview==
==Overview==
There are numerous teachers on physical examination that allow one to distinguish hypertrophic cardiomyopathy from other conditions such as [[aortic stenosis]]. On physical examination, (as shown in the table below) maneuvers that decrease left ventricular filling augment the [[murmur]] and maneuvers that increase afterload or filling decrease the murmur.
There are numerous findings on [[physical examination]] that allow one to distinguish hypertrophic cardiomyopathy from other conditions such as [[aortic stenosis]]. On [[physical examination]], (as shown in the table below) maneuvers that decrease [[left ventricular]] filling augment the [[murmur]] and maneuvers that increase [[afterload]] or filling decrease the [[Murmurs|murmur]].


==Physical Examination==
==Physical Examination==
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*[[Tachycardia]] with regular pulse or (ir)regularly irregular pulse
*[[Tachycardia]] with regular pulse or (ir)regularly irregular pulse
*Patients with hypertrophic cardiomyopathy are prone to arrhythmia
*Patients with hypertrophic cardiomyopathy are prone to [[Cardiac arrhythmia|arrhythmia]]


===Skin===
===Skin===
* Skin examination of patients with hypertrophic cardiomyopathy is usually normal.
*[[Skin]] examination of patients with hypertrophic cardiomyopathy is usually normal.


===HEENT===
===HEENT===
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*[[Jugular venous distension]]
*[[Jugular venous distension]]
** "[[A wave]]" is prominent on [[JVP]].
** "[[A wave]]" is prominent on [[JVP]].
**When CHF develops JVP is more prominent and [[Hepatojugular reflux]] might be present.
**When [[Congestive heart failure|CHF]] develops [[Jugular venous pressure|JVP]] is more prominent and [[Hepatojugular reflux]] might be present.
*[[Carotid bruits|Carotid]]
*[[Carotid bruits|Carotid]]
*Double carotid arterial pulse may be present.
*Double [[Carotid|carotid arterial]] pulse may be present.


===Lungs===
===Lungs===
* Pulmonary examination of patients with hypertrophic cardiomyopathy is usually normal.
*[[Pulmonary]] examination of patients with hypertrophic cardiomyopathy is usually normal.


===Heart===
===Heart===
* If dynamic outflow obstruction exists, physical examination findings that can be elicited include the pulsus bisferiens and the double apical impulse with each ventricular contraction. These findings, when present, can help differentiate HCM from [[aortic stenosis]].
* If dynamic outflow obstruction exists, [[physical examination]] findings that can be elicited include the [[pulsus bisferiens]] and the double apical impulse with each [[Ventricular|ventricular contraction]]. These findings, when present, can help differentiate HCM from [[aortic stenosis]].
* In addition, if the individual has [[premature ventricular contraction]]s (PVCs), the change in the carotid pulse intensity in the beat after the PVC can help differentiate HCM from aortic stenosis.
* In addition, if the individual has [[premature ventricular contraction]]s (PVCs), the change in the carotid pulse intensity in the beat after the PVC can help differentiate HCM from [[aortic stenosis]].
* In individuals with HCM, the pulse pressure will decrease in the beat after the PVC, while in aortic stenosis, the pulse pressure will increase.
* In individuals with HCM, the pulse pressure will decrease in the beat after the PVC, while in aortic stenosis, the [[pulse pressure]] will increase.


====Palpation====
====Palpation====
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=====Heart Sounds=====
=====Heart Sounds=====
* [[S1]] is normal.
* [[S1]] is normal.
* There may be paradoxically split S2 in severe cases
* There may be paradoxically split [[Heart sounds|S2]] in severe cases
* S3 gallop or S4 may also be present.
*[[S3 gallop]] or [[S4]] may also be present.
* S2 is louder in HCM than Aortic Stenosis.
*[[S2]] is louder in HCM than [[aortic stenosis]].
=====Murmurs=====
=====Murmurs=====
* The murmur is characteristically a crescendo-decrescendo [[systolic murmur]].
* The murmur is characteristically a crescendo-decrescendo [[systolic murmur]].
* Best heard between the apex and left sternal border.
* Best heard between the apex and left [[sternal]] border.
* It radiates to the suprasternal notch but not to the carotid arteries or neck thus differentiating it from aortic stenosis.
* It radiates to the [[suprasternal notch]] but not to the [[carotid arteries]] or neck thus differentiating it from [[aortic stenosis]].
* The cardiac [[heart murmur|murmur]] of HCM will sound similar to the murmur of [[aortic stenosis]]. However, this murmur will:
* The cardiac [[heart murmur|murmur]] of HCM will sound similar to the [[Heart murmur|murmur]] of [[aortic stenosis]]. However, this murmur will:
:* increase in intensity with any maneuver that decreases the volume of blood in the left ventricle (such as standing, [[valsalva maneuver]], amyl nitrate, diuretic administration or vasodilator administration).
 
:* increase in intensity with any maneuver that decreases the volume of blood in the left ventricle (such as standing, [[valsalva maneuver]], amyl nitrate, [[diuretic]] administration or [[Vasodilators|vasodilator]] administration).
:* decrease in intensity with any maneuver that increases the volume of blood in the left ventricle (such as Mueller maneuver, squatting or handgrip).
:* decrease in intensity with any maneuver that increases the volume of blood in the left ventricle (such as Mueller maneuver, squatting or handgrip).
* [[Hypertrophic cardiomyopathy]](HCM) can be differentiated from aortic stenosis by the fact that the murmur of aortic stenosis does not change substantially with maneuvers.
* [[Hypertrophic cardiomyopathy]](HCM) can be differentiated from aortic stenosis by the fact that the murmur of [[aortic stenosis]] does not change substantially with maneuvers.
* The character of the pulse in Aortic Stenosis is [[Pulsus parvus et tardus|parvus et tardus]], while a [[Pulsus bisferiens|bisferiens]] pulse is noted in HCM.
* The character of the pulse in [[aortic stenosis]] is [[Pulsus parvus et tardus|parvus et tardus]], while a [[Pulsus bisferiens|bisferiens]] pulse is noted in HCM.
* Associated murmurs:
* Associated murmurs:
:* 10% of the patients with HCM will also present with aortic regurgitation and in that case, a diastolic decrescendo murmur may be present.
 
:* If mitral regurgitation co exists with HCM then a holosystolic murmur will be beast heard at the caridac apex and left axilla.
:* 10% of the patients with HCM will also present with [[aortic regurgitation]] and in that case, a [[Diastolic murmurs|diastolic]] decrescendo murmur may be present.
:* If [[mitral regurgitation]] coexists with HCM then a [[holosystolic murmur]] will be beast heard at the caridac apex and left [[axilla]].


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<br />
<br />
===Abdomen===
===Abdomen===
* Abdominal examination of patients with hypertrophic cardiomyopathy is usually normal.
*[[Abdominal]] examination of patients with hypertrophic cardiomyopathy is usually normal.


===Back===
===Back===
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===Genitourinary===
===Genitourinary===
* Genitourinary examination of patients with hypertrophic cardiomyopathy is usually normal.
*[[Genitourinary system|Genitourinary]] examination of patients with hypertrophic cardiomyopathy is usually normal.


===Neuromuscular===
===Neuromuscular===
* Neuromuscular examination of patients with hypertrophic cardiomyopathy is usually normal.
*[[Neuromuscular]] examination of patients with hypertrophic cardiomyopathy is usually normal.


===Extremities===
===Extremities===

Latest revision as of 17:54, 5 February 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

There are numerous findings on physical examination that allow one to distinguish hypertrophic cardiomyopathy from other conditions such as aortic stenosis. On physical examination, (as shown in the table below) maneuvers that decrease left ventricular filling augment the murmur and maneuvers that increase afterload or filling decrease the murmur.

Physical Examination

  • The physical findings of HCM are associated with the dynamic outflow obstruction that is often present with this disease.[1][2][3][4][5] [6][7][8][9]

Appearance of the Patient

  • Patients with hypertrophic cardiomyopathy usually appear normal.

Vital Signs

  • Tachycardia with regular pulse or (ir)regularly irregular pulse
  • Patients with hypertrophic cardiomyopathy are prone to arrhythmia

Skin

  • Skin examination of patients with hypertrophic cardiomyopathy is usually normal.

HEENT

  • HEENT examination of patients with hypertrophic cardiomyopathy is usually normal.

Neck

Lungs

  • Pulmonary examination of patients with hypertrophic cardiomyopathy is usually normal.

Heart

Palpation

  • Powerful apical precordial impulse is present which may be shifted laterally.

Auscultation

Heart Sounds
Murmurs
  • increase in intensity with any maneuver that decreases the volume of blood in the left ventricle (such as standing, valsalva maneuver, amyl nitrate, diuretic administration or vasodilator administration).
  • decrease in intensity with any maneuver that increases the volume of blood in the left ventricle (such as Mueller maneuver, squatting or handgrip).
Differentiating hypertrophic cardiomyopathy and valvular aortic stenosis
  Aortic stenosis Hypertrophic cardiomyopathy
Echocardiography
Aortic valve calcification Common No
Dilated ascending aorta Common Rare
Ventricular hypertrophy Concentric LVH Asymmetric, often involving the septum
Physical examination
Murmur of AI Common No
Pulse pressure after PVC Increased Decreased
Valsalva maneuver Decreased intensity of murmur Increased intensity of murmur
Carotid pulsation Normal or tardus et parvus Brisk, jerky, or bisferiens pulse (a collapse of the pulse followed by a secondary rise)


Abdomen

  • Abdominal examination of patients with hypertrophic cardiomyopathy is usually normal.

Back

  • Back examination of patients with hypertrophic cardiomyopathy is usually normal.

Genitourinary

  • Genitourinary examination of patients with hypertrophic cardiomyopathy is usually normal.

Neuromuscular

  • Neuromuscular examination of patients with hypertrophic cardiomyopathy is usually normal.

Extremities

  • Extremities examination of patients with hypertrophic cardiomyopathy is usually normal.


References

  1. Maron BJ. Hypertrophic cardiomyopathy. Lancet 1997;350:127–33.
  2. Maron BJ. Hypertrophic cardiomyopathy. A systematic review. JAMA 2002;287:1308–20.
  3. Maki S, Ikeda H, Muro A et al. Predictors of sudden cardiac death in hypertrophic cardiomyopathy. Am J Cardiol 1998;82:774–8.
  4. Maron BJ, Casey SA, Poliac LC, Gohman TE, Almquist AK, Aeppli DM. Clinical course of hypertrophic cardiomyopathy in a regional United States cohort. JAMA 1999;281:650–5.
  5. Maron BJ, Olivotto I, Bellone P et al. Clinical profile of stroke in 900 patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 2002;39:301–7.
  6. Maron BJ. Hypertrophic cardiomyopathy. A systematic review. JAMA 2002;287:1308–20.
  7. Maron BJ, Casey SA, Poliac LC, Gohman TE, Almquist AK, Aeppli DM. Clinical course of hypertrophic cardiomyopathy in a regional United States cohort. JAMA 1999;281:650–5.
  8. Fay WP, Taliercio CP, Ilstrup DM, Tajik AJ, Gersh BJ. Natural history of hypertrophic cardiomyopathy in the elderly. J Am Coll Cardiol 1990;16:821–6.
  9. Takagi E, Yamakado T, Nakano T. Prognosis of completely asymptomatic adult patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 1999;33:206–11.

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