De Quervain's thyroiditis: Difference between revisions

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{{CMG}} {{AE}} {{MMF}}
{{CMG}} {{AE}} {{MMF}}
{{SK}} Subacute granulomatous thyroiditis; subacute thyroiditis
{{SK}} Subacute granulomatous thyroiditis; subacute thyroiditis


==Overview==
==Overview==

Revision as of 14:30, 1 August 2017

De Quervain's thyroiditis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating De Quervain's thyroiditis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary prevention

Secondary prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Synonyms and keywords: Subacute granulomatous thyroiditis; subacute thyroiditis

Overview

De Quervain's thyroiditis usually occurs in women between 30 and 50 years of age. It is a member of the group of thyroiditis conditions known as resolving thyroiditis.

Historical Perspective

It is named for Fritz de Quervain.[1] It should not be confused with DeQuervain's syndrome.

Classification

Pathophysiology

Causes

Some cases may be viral in origin, perhaps preceded by an upper respiratory tract infection. Some cases develop postpartum.

Differentiating De Quervain's thyroiditis from other Conditions

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Patients will experience a hyperthyroid period as the cellular lining of colloid spaces fails, allowing abundant colloid into the circulation, with neck pain and fever. Patients typically then become hypothyroid as the pituitary reduces TSH production and the inappropriately released colloid is depleted before resolving to euthyroid. The symptoms are those of hyperthyroidism and hypothyroidism. In addition, patients may suffer from painful dysphagia. There are multi-nucleated giant cells on histology.

Laboratory Findings

Electrocardiogram

Chest X Ray

Echocardiography or Ultrasound

Other Imaging Findings

Treatment

Medical Therapy

Treatment is NSAID.

Corticosteroids may be of help in refractory cases.

Surgery

Primary prevention

Secondary Prevention

Overview

de Quervain's thyroiditis usually occurs in women between 30 and 50 years of age. It is a member of the group of thyroiditis conditions known as resolving thyroiditis.


Causes

Some cases may be viral in origin, perhaps preceded by an upper respiratory tract infection. Some cases develop postpartum.


References


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