Carcinoid syndrome history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Symptoms of carcinoid tumor include [[flushing]], [[diarrhea | Symptoms of [[carcinoid tumor]] include [[flushing]], [[diarrhea]], [[abdominal cramps]], [[wheezing]], and [[cough]]. | ||
==History== | ==History== | ||
When evaluating a patient for carcinoid syndrome, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough past medical history review. Other specific areas of focus when obtaining the history are: | When evaluating a patient for [[Carcinoid Syndrome|carcinoid syndrome]], you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated [[symptoms]], and a thorough [[past medical history]] review. Other specific areas of focus when obtaining the history are: | ||
*Review of any family history of predisposing genetic disorders such as [[multiple endocrine neoplasia type 1]] or [[neurofibromatosis type 1]] | *Review of any family history of predisposing genetic disorders such as [[multiple endocrine neoplasia type 1]] or [[neurofibromatosis type 1]]. | ||
==Symptoms== | ==Symptoms== | ||
===Carcinoid Syndrome=== | ===Carcinoid Syndrome=== | ||
Common symptoms of carcinoid syndrome include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of [[Carcinoid Syndrome|carcinoid syndrome]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
* [[Flushing (physiology)|Flushing]] | * [[Flushing (physiology)|Flushing]] | ||
* [[Diarrhea]] | * [[Diarrhea]] | ||
* [[Wheezing]] | * [[Wheezing]] | ||
* [[Abdominal cramps|Abdominal cramping]] | * [[Abdominal cramps|Abdominal cramping]] | ||
* | * [[Leg edema]] | ||
*[[Shortness of breath]] | *[[Shortness of breath]] | ||
*[[Palpitations]] | *[[Palpitations]] | ||
| Line 22: | Line 23: | ||
*[[Hirsutism]] | *[[Hirsutism]] | ||
*[[Weakness]] | *[[Weakness]] | ||
This constellation of symptoms is called | This constellation of [[symptoms]] is called [[Carcinoid Syndrome|carcinoid syndrome]] or (if [[acute]]) [[carcinoid crisis]]. Occasionally, [[hemorrhage]] or pressure effects of the [[tumor]] are the presenting [[symptoms]]. | ||
===Gastrointestinal Carcinoid Tumor=== | ===Gastrointestinal Carcinoid Tumor=== | ||
Common symptoms of gastrointestinal carcinoid tumor include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of [[gastrointestinal]] [[carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*[[Abdominal pain]] | *[[Abdominal pain]] | ||
*[[Diarrhea]] | *[[Diarrhea]] | ||
| Line 31: | Line 32: | ||
*[[Rash]] | *[[Rash]] | ||
*[[Gastrointestinal bleeding]] | *[[Gastrointestinal bleeding]] | ||
*[[Pellagra]], which causes scale-like skin sores, [[diarrhea]], and mental disturbances | *[[Pellagra]], which causes scale-like [[skin]] [[sores]], [[diarrhea]], and [[mental]] disturbances | ||
*[[Melena]] | *[[Melena]] | ||
*[[Nausea]] | *[[Nausea]] | ||
*[[Vomiting]] | *[[Vomiting]] | ||
*[[Jaundice]] | *[[Jaundice]] | ||
===Duodenal Carcinoid Tumor=== | |||
Common symptoms of duodenal [[Carcinoid tumors|carcinoid tumor]] due to [[gastrin]] overproduction include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | |||
*[[Nausea]] | |||
*[[Vomiting]] | |||
*[[Abdominal pain]] | |||
*[[Hemorrhage]] from multiple and recurrent [[peptic ulcers]] | |||
*[[Gastroesophageal reflux]] | |||
*[[Diarrhea]] from [[hypergastrinemia]] | |||
===Jejunal and Ileal Carcinoid Tumor=== | |||
Common symptoms of [[Jejunum|jejunal]] and [[Ileum|ileal]] [[Carcinoid tumors|carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | |||
*[[Small intestinal]] [[obstruction]] | |||
*[[Hemorrhage]] | |||
*Intermitten[[Crampy|t crampy]] [[abdominal pain]] | |||
*[[Weight loss]] | |||
*[[Fatigue]] | |||
*[[Abdominal distention]] | |||
*[[Diarrhea]] | |||
*[[Nausea]] | |||
*[[Vomiting]] | |||
===Colorectal carcinoid Tumor=== | |||
Common symptoms of [[colorectal]] [[Carcinoid tumors|carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | |||
*[[Hemorrhage]] | |||
*[[Abdominal pain]] | |||
*[[Constipation]] | |||
===Lung Carcinoid Tumor=== | ===Lung Carcinoid Tumor=== | ||
Common symptoms of lung carcinoid tumor include: | Common [[symptoms]] of [[lung]] [[Carcinoid tumors|carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*Post-obstructive [[pneumonia]] | *Post-obstructive [[pneumonia]] | ||
*[[Wheezing]] | *[[Wheezing]] | ||
| Line 44: | Line 82: | ||
===Thymic Carcinoid=== | ===Thymic Carcinoid=== | ||
Thymic carcinoid causes [[Cushing syndrome]] as a result of [[adrenocorticotropic hormone]] secretion by the tumor. Common symptoms of [[Cushing syndrome]] include: | [[Thymic]] [[carcinoid]] causes [[Cushing syndrome]] as a result of [[adrenocorticotropic hormone]] secretion by the [[tumor]]. Common symptoms of [[Cushing syndrome]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
* | *[[Obesity|Central obesity]] | ||
*[[Moon face]] | *[[Moon face]] | ||
*[[Diaphoresis]] | *[[Diaphoresis]] | ||
| Line 53: | Line 91: | ||
*[[Amenorrhoea]] | *[[Amenorrhoea]] | ||
*[[Infertility]] | *[[Infertility]] | ||
*[[Mood disorders]] | *[[Mood disorders]]<ref>{{cite book |title=The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences |last=Yudofsky |first=Stuart C. |coauthors=Robert E. Hales |edition=5th |year=2007 |publisher=American Psychiatric Pub, Inc. |isbn=1585622397 }}</ref> | ||
=== | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Symptoms of carcinoid tumor include flushing, diarrhea, abdominal cramps, wheezing, and cough.
History
When evaluating a patient for carcinoid syndrome, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough past medical history review. Other specific areas of focus when obtaining the history are:
- Review of any family history of predisposing genetic disorders such as multiple endocrine neoplasia type 1 or neurofibromatosis type 1.
Symptoms
Carcinoid Syndrome
Common symptoms of carcinoid syndrome include:[1]
- Flushing
- Diarrhea
- Wheezing
- Abdominal cramping
- Leg edema
- Shortness of breath
- Palpitations
- Weight gain
- Hirsutism
- Weakness
This constellation of symptoms is called carcinoid syndrome or (if acute) carcinoid crisis. Occasionally, hemorrhage or pressure effects of the tumor are the presenting symptoms.
Gastrointestinal Carcinoid Tumor
Common symptoms of gastrointestinal carcinoid tumor include:[1]
- Abdominal pain
- Diarrhea
- Facial flushing
- Rash
- Gastrointestinal bleeding
- Pellagra, which causes scale-like skin sores, diarrhea, and mental disturbances
- Melena
- Nausea
- Vomiting
- Jaundice
Duodenal Carcinoid Tumor
Common symptoms of duodenal carcinoid tumor due to gastrin overproduction include:[1]
- Nausea
- Vomiting
- Abdominal pain
- Hemorrhage from multiple and recurrent peptic ulcers
- Gastroesophageal reflux
- Diarrhea from hypergastrinemia
Jejunal and Ileal Carcinoid Tumor
Common symptoms of jejunal and ileal carcinoid tumor include:[1]
- Intermittent crampy abdominal pain
Colorectal carcinoid Tumor
Common symptoms of colorectal carcinoid tumor include:[1]
Lung Carcinoid Tumor
Common symptoms of lung carcinoid tumor include:[1]
Thymic Carcinoid
Thymic carcinoid causes Cushing syndrome as a result of adrenocorticotropic hormone secretion by the tumor. Common symptoms of Cushing syndrome include:[1]
- Central obesity
- Moon face
- Diaphoresis
- Insomnia
- Decreased libido
- Impotence
- Amenorrhoea
- Infertility
- Mood disorders[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq
- ↑ Yudofsky, Stuart C. (2007). The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences (5th ed.). American Psychiatric Pub, Inc. ISBN 1585622397. Unknown parameter
|coauthors=ignored (help)