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==Overview==
==Overview==
== Medical Therapy ==
== Medical Therapy ==
* Mainstay of treatment of nausea and vomiting is correcting any electrolyte imbalance, dehydration, malnutrition, and suppression of symptoms while evaluating and treating the underlying cause.
* Fluid resuscitation (due to vomiting-induced dehydration)
* Fluid resuscitation (due to vomiting-induced dehydration)
* Treat underlying disease etiologies
* Treat underlying disease etiologies
* Dietary recommendations include a low-fat, low-fiber diet with frequent small meals if able to tolerate oral intake. Liquid diet is recommended in case solid diet is not well tolerated. <ref name="pmid26770271">{{cite journal |vauthors=Singh P, Yoon SS, Kuo B |title=Nausea: a review of pathophysiology and therapeutics |journal=Therap Adv Gastroenterol |volume=9 |issue=1 |pages=98–112 |date=January 2016 |pmid=26770271 |pmc=4699282 |doi=10.1177/1756283X15618131 |url=}}</ref>
* Ginger has some efficacy to reduce post-operative nausea and vomiting, morning sickness and motion sickness. <ref name="pmid10793599">{{cite journal |vauthors=Ernst E, Pittler MH |title=Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials |journal=Br J Anaesth |volume=84 |issue=3 |pages=367–71 |date=March 2000 |pmid=10793599 |doi=10.1093/oxfordjournals.bja.a013442 |url=}}</ref> <ref name="pmid12233808">{{cite journal |vauthors=Keating A, Chez RA |title=Ginger syrup as an antiemetic in early pregnancy |journal=Altern Ther Health Med |volume=8 |issue=5 |pages=89–91 |date=2002 |pmid=12233808 |doi= |url=}}</ref>
* Alternative approaches include hypnosis, acupressure and acupuncture. <ref name="pmid10971166">{{cite journal |vauthors=Marchioro G, Azzarello G, Viviani F, Barbato F, Pavanetto M, Rosetti F, Pappagallo GL, Vinante O |title=Hypnosis in the treatment of anticipatory nausea and vomiting in patients receiving cancer chemotherapy |journal=Oncology |volume=59 |issue=2 |pages=100–4 |date=August 2000 |pmid=10971166 |doi=10.1159/000012144 |url=}}</ref> <ref name="pmid19370583">{{cite journal |vauthors=Lee A, Fan LT |title=Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting |journal=Cochrane Database Syst Rev |volume= |issue=2 |pages=CD003281 |date=April 2009 |pmid=19370583 |pmc=3113464 |doi=10.1002/14651858.CD003281.pub3 |url=}}</ref>





Revision as of 03:32, 18 January 2021

Nausea and vomiting Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: {{VVS}

Overview

Medical Therapy

  • Mainstay of treatment of nausea and vomiting is correcting any electrolyte imbalance, dehydration, malnutrition, and suppression of symptoms while evaluating and treating the underlying cause.
  • Fluid resuscitation (due to vomiting-induced dehydration)
  • Treat underlying disease etiologies
  • Dietary recommendations include a low-fat, low-fiber diet with frequent small meals if able to tolerate oral intake. Liquid diet is recommended in case solid diet is not well tolerated. [1]
  • Ginger has some efficacy to reduce post-operative nausea and vomiting, morning sickness and motion sickness. [2] [3]
  • Alternative approaches include hypnosis, acupressure and acupuncture. [4] [5]


Treatment of Nausea

While short-term nausea and vomiting are generally harmless, they may sometimes indicate a more serious condition, such as Coeliac disease. When associated with prolonged vomiting, it may lead to dehydration and/or dangerous electrolyte imbalances.

Symptomatic treatment for nausea and vomiting may include short-term avoidance of solid food. This is usually easy as nausea is nearly always associated with loss of appetite. Dehydration may require rehydration with oral or intravenous electrolyte solutions. If the cause is by motion sickness, sitting down in a still environment may also help.

There are several types of antiemetics, and researchers continue to look for more effective treatments. The main types used post operatively for surgical patients are ondansetron, dexamethasone, promethazine, diphenhydramine, and in small doses droperidol. Doxylamine is the drug of choice in pregnancy-related nausea. Anecdotally, another remedy used by recovery room nurses is to place an isopropyl alcohol swab under the patient's nose while he or she breathes through the nose. This may abate the nausea until the antiemetic medication takes effect. When ingested or inhaled, the chemical compound tetrahydrocannabinol has been shown to reduce nausea in some users.[6] Also available are a variety of non-invasive (often untested) mechanical devices used to suppress nausea due to motion sickness.

The spice ginger is also used for centuries as a folk remedy to treat nausea, and recent research has supported this use.[7]

Treatment of Vomiting

Acute Pharmacotherapies

  • Antiemetics: An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of some opioid analgesics and chemotherapy directed against cancer. Antiemetics act by inhibiting the receptor sites associated with emesis. Hence, anticholinergics, antihistamines, dopamine antagonists, serotonin antagonists and cannabinoids are used as anti-emetics.
  • Anticholinergics

References

  1. Singh P, Yoon SS, Kuo B (January 2016). "Nausea: a review of pathophysiology and therapeutics". Therap Adv Gastroenterol. 9 (1): 98–112. doi:10.1177/1756283X15618131. PMC 4699282. PMID 26770271.
  2. Ernst E, Pittler MH (March 2000). "Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials". Br J Anaesth. 84 (3): 367–71. doi:10.1093/oxfordjournals.bja.a013442. PMID 10793599.
  3. Keating A, Chez RA (2002). "Ginger syrup as an antiemetic in early pregnancy". Altern Ther Health Med. 8 (5): 89–91. PMID 12233808.
  4. Marchioro G, Azzarello G, Viviani F, Barbato F, Pavanetto M, Rosetti F, Pappagallo GL, Vinante O (August 2000). "Hypnosis in the treatment of anticipatory nausea and vomiting in patients receiving cancer chemotherapy". Oncology. 59 (2): 100–4. doi:10.1159/000012144. PMID 10971166.
  5. Lee A, Fan LT (April 2009). "Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting". Cochrane Database Syst Rev (2): CD003281. doi:10.1002/14651858.CD003281.pub3. PMC 3113464. PMID 19370583.
  6. Drug Policy Alliance (2001). "Medicinal Uses of Marijuana: Nausea, Emesis and Appetite Stimulation". Retrieved 2007-08-02.
  7. University of Maryland Medical Centre (2006). "Ginger". Retrieved 2007-08-02.

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