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==Overview==
==Overview==
Symptoms of nephrotic syndrome include [[edema]], [[dyspnea]], [[abdominal fullness]], [[anorexia]], and [[fatigue]].
The hallmark of nephrotic syndrome is [[edema]]. A positive history of renal disease, systemic diseases such as [[diabetes mellitus]], [[amyloidosis]], or [[systemic lupus erythematosus]], and medication use is suggestive of nephrotic syndrome. The most common symptoms of nephrotic syndrome include volume overload, foamy urine, and [[fatigue]].
==Symptoms==
==History and Symptoms==
*[[Swelling]], especially in the lower extremities and genitals or [[anasarca]]
* The hallmark of nephrotic syndrome is [[edema]]. A positive history of renal disease, systemic diseases such as [[diabetes mellitus]], [[amyloidosis]], or [[systemic lupus erythematosus]], and medication use is suggestive of nephrotic syndrome. The most common symptoms of nephrotic syndrome include volume overload, foamy urine, and [[fatigue]].<ref name="Liebeskind2014">{{cite journal|last1=Liebeskind|first1=David S.|title=Nephrotic syndrome|volume=119|year=2014|pages=405–415|issn=00729752|doi=10.1016/B978-0-7020-4086-3.00026-6}}</ref><ref name="SinhaBagga2012">{{cite journal|last1=Sinha|first1=Aditi|last2=Bagga|first2=Arvind|title=Nephrotic Syndrome|journal=The Indian Journal of Pediatrics|volume=79|issue=8|year=2012|pages=1045–1055|issn=0019-5456|doi=10.1007/s12098-012-0776-y}}</ref>
*[[Dyspnea]] suggestive of [[pleural effusion]]
 
*[[Abdominal fullness]] suggestive of [[ascites]]
=== History ===
*Symptoms of [[high blood pressure]], such as [[headache]] and [[visual disturbance]]
Patients with nephrotic syndrome may have a positive history of:
*Symptoms of [[proteinuria]], such as [[foamy urine]]
* [[Kidney|Renal disease]]
*[[Weight gain]]
* Systemic disease such as [[diabetes mellitus]], [[amyloidosis]], or [[systemic lupus erythematosus]]
*[[Fatigue]]
* Medication use
 
=== Common Symptoms ===
Common symptoms of nephrotic syndrome include:
*Symptoms of [[proteinuria]], such as foamy urine
*Volume overload that manifests as:
**[[Swelling]] of lower extremities and genitals
**[[Abdominal fullness]] suggestive of [[ascites]]
**[[Anasarca]]
**[[Dyspnea]] suggestive of [[pulmonary edema]]
**[[Weight gain]]
 
=== Less Common Symptoms ===
Less common symptoms of nephrotic syndrome include:
* [[Fatigue]]
*[[Anorexia]]
*[[Anorexia]]
*Features of systemic disease
*Symptoms of associated complications
*Drug history
**Symptoms of [[high blood pressure]], such as [[headache]] and [[visual disturbance]]
*Symptoms of associated complications, such as symptoms of [[deep vein thrombosis]] or [[pulmonary edema]]
**Symptoms of [[deep vein thrombosis]]  
**Symptoms of [[Infection|infections]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Kidney diseases]]
[[Category:Medicine]]
[[Category:Nephrology]]
[[Category:Nephrology]]
[[Category:Pediatrics]]
[[Category:Up-To-Date]]
[[Category:Disease]]
[[Category:Emergency medicine]]
[[Category:Syndromes]]
[[Category:Primary care]]
[[Category:Needs content]]
[[Category:Needs overview]]
 
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Latest revision as of 22:57, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian

Overview

The hallmark of nephrotic syndrome is edema. A positive history of renal disease, systemic diseases such as diabetes mellitus, amyloidosis, or systemic lupus erythematosus, and medication use is suggestive of nephrotic syndrome. The most common symptoms of nephrotic syndrome include volume overload, foamy urine, and fatigue.

History and Symptoms

History

Patients with nephrotic syndrome may have a positive history of:

Common Symptoms

Common symptoms of nephrotic syndrome include:

Less Common Symptoms

Less common symptoms of nephrotic syndrome include:

References

  1. Liebeskind, David S. (2014). "Nephrotic syndrome". 119: 405–415. doi:10.1016/B978-0-7020-4086-3.00026-6. ISSN 0072-9752.
  2. Sinha, Aditi; Bagga, Arvind (2012). "Nephrotic Syndrome". The Indian Journal of Pediatrics. 79 (8): 1045–1055. doi:10.1007/s12098-012-0776-y. ISSN 0019-5456.