Ulcerative colitis secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]


Due to the risk of colon cancer associated with ulcerative colitis. screening with colonoscopy is recommended for secondary prevention of ulcerative colitis. Adherence to maintenance therapy is recommended for secondary prevention of acute exacerbation of colitis.[1]

Secondary Prevention

Due to the risk of colon cancer associated with ulcerative colitis, screening with colonoscopy is recommended. The American Cancer Society recommends the following schedule for colonoscopy:[1]

  • First colonoscopy 8 years after diagnosis with severe disease, or when most of, or the entire, large intestine is involved
  • First colonoscopy 12 - 15 years after diagnosis when only the left side of the large intestine is involved
  • Follow-up colonoscopy should be performed every 1 - 2 years


  1. 1.0 1.1 Kornbluth A, Sachar DB, Practice Parameters Committee of the American College of Gastroenterology (2010). "Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee". Am J Gastroenterol. 105 (3): 501–23, quiz 524. doi:10.1038/ajg.2009.727. PMID 20068560.

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