Sandbox: malabsorption: Difference between revisions

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*Dehydration
*[[Dehydration]]
*Diffuse [[abdominal tenderness]]
*Diffuse [[abdominal tenderness]]
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*
*[[Dehydration]]
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*Diffuse [[abdominal tenderness]]
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*Positive [[stool culture]]
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*
*
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*Enterotoxins:
**Heat–labile enterotoxin (LT) 
**Heat–stable enterotoxin (ST)
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*Enterotoxins:
*[[Escherichia coli|Enterotoxigenic escherichia coli]]
**Heat–labile enterotoxin (LT)
*[[Enterotoxin|Enterotoxins]]:
**Heat–stable enterotoxin (ST)
**Heat–labile [[enterotoxin]] (LT)
**Heat–stable [[enterotoxin]] (ST)
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*
*[[Stool culture]]
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| style="background:#DCDCDC;" align="center" |[[EPEC|'''EPEC''']]
| style="background:#DCDCDC;" align="center" |[[EPEC|'''EPEC''']]
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| style="background:#DCDCDC;" align="center" |[[EIEC|'''EIEC''']]
| style="background:#DCDCDC;" align="center" |[[EIEC|'''EIEC''']]
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| style="background:#DCDCDC;" align="center" |[[EHEC|'''EHEC''']]
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| style="background:#DCDCDC;" align="center" |[[EAEC|'''EAEC''']]
| style="background:#DCDCDC;" align="center" |[[EAEC|'''EAEC''']]
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! colspan="2" style="background:#DCDCDC;" align="center" |[[Yersinia enterocolitica]]
! colspan="2" style="background:#DCDCDC;" align="center" |[[Yersinia enterocolitica]]
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! colspan="2" style="background:#DCDCDC;" align="center" |[[Vibrio cholerae|Vibrio cholera]]
! colspan="2" style="background:#DCDCDC;" align="center" |[[Vibrio cholerae|Vibrio cholera]]
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! colspan="2" style="background:#DCDCDC;" align="center" |[[Aeromonas]]
! colspan="2" style="background:#DCDCDC;" align="center" |[[Aeromonas]]
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! colspan="2" style="background:#DCDCDC;" align="center" |[[Plesiomonas shigelloides|Plesiomonas]]
! colspan="2" style="background:#DCDCDC;" align="center" |[[Plesiomonas shigelloides|Plesiomonas]]
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! colspan="2" style="background:#DCDCDC;" align="center" |[[Mycobacterium avium complex]]
! colspan="2" style="background:#DCDCDC;" align="center" |[[Mycobacterium avium complex]]
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Revision as of 20:19, 14 December 2017

Diarrhea

Abbreviations: GI: Gastrointestinal, CBC: Complete blood count, WBC: White blood cell, RBC: Red blood cell, Plt: Platelet, Hgb: Hemoglobin, ESR: Erythrocyte sedimentation rate, CRP: C–reactive protein, IgE: Immunoglobulin E, IgA: Immunoglobulin A, ETEC: Escherichia coli enteritis, EPEC: Enteropathogenic Escherichia coli, EIEC: Enteroinvasive Escherichia coli, EHEC: Enterohemorrhagic Escherichia coli, EAEC: Enteroaggregative Escherichia coli,

Categories Cause Clinical manifestation Lab findings Extra intestinal findings Cause/Pathogenesis Gold standard diagnosis
Symptoms GI signs
Duration Diarrhea Fever Abdominal pain Weight loss
Stool exam CBC Other lab findings
Acute Chronic Watery Bloody Fatty WBC RBC Ova/Parasite Osmotic gap Other WBC Hgb Plt
Gastrointestinal Crohns disease + + + + ± + + + +
  • Abnormal immune response to self antigens
Ulcerative colitis + + + + + + + + +
  • Abnormal immune response to self antigens
Celiac disease + ± ± + +
Cystic fibrosis + + ± + +
Chronic pancreatitis + + + + +
Bile acid malabsorption + + + +
Microscopic colitis + + + +
Infective colitis + + + - + + + + + +
Ischemic colitis + + + + - + + + + +
Lactose intolerance + + + +
Irritable bowel syndrome + ± ± ±
  • Diagnosis of exclusion
Infection Bacterial Whipple's disease + + + ± + + ↓/↑
Tropical sprue + + + + + + + +
  • Diagnosis of exclusion
Small bowel bacterial overgrowth + + + + + +
  • Diagnosis of exclusion
Pseudomembranous enterocolitis + + ± + + ± + +
Shigellosis + + + + + + + ↑/↓
Salmonellosis + + + + + + + + -
 Campylobacteriosis + + + + + + +
E–coli ETEC

(Traveler's diarrhea)

+ + + +
EPEC +
EIEC +
EHEC +
EAEC +
Yersinia enterocolitica +
Vibrio cholera +
Aeromonas +
Plesiomonas +
Mycobacterium avium complex + + + +/– +
+/– +
  • Immune system analysis may show defects
Other infections
  • aaaa
  • bbbb
+ + + +/–
+ +
  • Stool culture may be positive for responsible organism
Virus Rotavirus
Echovirus
Adenovirus
Norovirus
CMV colitis + + +/– +
+/– +
  • CD 4 level decreased as it is maily associated with HIV
HIV
Hepatitis Hepatitis A
Hepatitis E
Parasite Entamoeba histolytica
+
Giardia
+
Cryptosporidium
+
Microsporidia
+
Isospora + + +
+ + +
Other Parasitic diarrhea
  • aaaa
  • bbbb
+ + + + +/–
+ + +
Tumors Carcinoid tumor
VIPoma + + + + + +
  • Primary secretory tumor
  • Elevated VIP levels
  • Followed by imaging
Zollinger–Ellison syndrome + + + + +
  • Elevated basal or stimulated serum gastrin> 120 pg/mL
Somatostatinoma
Lymphoma
Colorectal cancer + + + +
+
↑/↓
  • May be associated with FAP gene or HNPCC gene
Medication/Toxicity Drug induced enteritis
Laxative abuse
Heavy metal ingestion
Organophosphate poisoning
Opium withdrawal
Iatrogenic Short bowel syndrome + + + + +
  • Surgical intestinal resection
Radiation enteritis
Dumping syndrome
Others Abetalipoproteinemia + + + + +
Hyperthyroidism + + ± + +
  • Elevated T4
  • Elevated T3
  • Decreased TSH
Diabetic neuropathy
Systemic sclerosis